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ONTOLOGY REPORT - ANNOTATIONS

Term:2-oxoglutarate metabolic process
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Accession:GO:0006103 term browser browse the term
Definition:The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.
Synonyms:exact_synonym: 2-ketoglutarate metabolic process;   2-ketoglutarate metabolism;   2-oxoglutarate metabolism;   alpha-ketoglutarate metabolic process;   alpha-ketoglutarate metabolism;   alpha-oxoglutarate metabolic process;   alpha-oxoglutarate metabolism


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2-oxoglutarate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase involved_in ISO
IEA
ISS		 (PMID:18620547)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18620547 GO_REF:0000024 GO_REF:0000107 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G AC132020.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 9:76,367,193...76,367,615 JBrowse link
G Col6a1 collagen type VI alpha 1 chain acts_upstream_of_or_within ISO MGI:2153356 (PMID:23437220) RGD PMID:23437220 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Dld dihydrolipoamide dehydrogenase IDA RGD PMID:3571202 RGD:2306876 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase involved_in IDA
ISO		 (PMID:10806400) RGD PMID:10806400 PMID:3571202 RGD:2306876 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 involved_in ISO (PMID:11863375) RGD PMID:11863375 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 involved_in ISO
ISS		 (PMID:19935646)
GO_REF:0000024		 RGD
UniProt		 PMID:19935646 GO_REF:0000024 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Kgd4 alpha-ketoglutarate dehydrogenase subunit 4 involved_in ISO (MGI:6810699|PMID:25165143), (MGI:7564183|PMID:36854377) RGD PMID:25165143 PMID:36854377 MGI:6810699 MGI:7564183 NCBI chr 2:31,870,549...31,878,335
Ensembl chr 2:31,870,551...31,880,730 		JBrowse link
G Kyat3 kynurenine aminotransferase 3 involved_in ISO
IEA		 (MGI:3835225|PMID:19029248)
GO_REF:0000107		 RGD
Ensembl		 PMID:19029248 GO_REF:0000107 MGI:3835225 NCBI chr 2:231,701,881...231,747,462
Ensembl chr 2:231,701,963...231,747,227 		JBrowse link
G Ogdh oxoglutarate dehydrogenase involved_in IDA
IEA
ISO		 GO_REF:0000107
(PMID:24495017), (PMID:29211711)		 Ensembl
RGD		 PMID:24495017 PMID:29211711 PMID:3571202 PMID:9712727 GO_REF:0000107, RGD:2306876, RGD:2306877 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479 		JBrowse link
G Ogdhl oxoglutarate dehydrogenase L involved_in IDA PMID:18783430 UniProt PMID:18783430 RGD:42721998 NCBI chr16:7,578,343...7,604,385
Ensembl chr16:7,578,367...7,604,386 		JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase involved_in ISO (PMID:16186124) RGD PMID:16186124 NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409 		JBrowse link
G Tat tyrosine aminotransferase involved_in ISO (PMID:7999802)
(MGI:5430853|PMID:21153519)		 RGD PMID:7999802 PMID:21153519 MGI:5430853 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
glutamate catabolic process to 2-oxoglutarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO		 GO_REF:0000107
(PMID:4193185)		 Ensembl
RGD		 PMID:4193185 PMID:16489927 GO_REF:0000107, RGD:13504861 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within IDA
ISO		 (PMID:4193185) RGD PMID:4193185 PMID:16489927 RGD:13504861 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
glutamate catabolic process via 2-oxoglutarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adhfe1 alcohol dehydrogenase, iron containing, 1 involved_in ISO
IEA
ISS		 (PMID:16435184)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:16435184 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11455
      cellular metabolic process 9554
        organic acid metabolic process 1021
          oxoacid metabolic process 1010
            carboxylic acid metabolic process 995
              dicarboxylic acid metabolic process 101
                2-oxoglutarate metabolic process 17
                  L-arabinose catabolic process to 2-oxoglutarate 0
                  L-histidine catabolic process to 2-oxoglutarate 0
                  acetyl-CoA assimilation pathway 0
                  glutamate catabolic process to 2-oxoglutarate 2
                  glutamate catabolic process via 2-oxoglutarate 1
                  mixed acid fermentation 0
                  proline catabolic process to 2-oxoglutarate 0
paths to the root