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ONTOLOGY REPORT - ANNOTATIONS

Term:hypersensitivity
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Accession:GO:0002524 term browser browse the term
Definition:An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.
Synonyms:related_synonym: hypersensitivity response
 xref: Wikipedia:Hypersensitivity


show annotations for term's descendants           Sort by:
hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (PMID:21093315) RGD PMID:21093315 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr1a Fc gamma receptor 1A involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:11711607)
MGI:2664927|MGI:2679238 (PMID:11911823), (PMID:11911824)
GO_REF:0000033		 RGD
GO_Central		 PMID:11711607 PMID:11911823 PMID:11911824 GO_REF:0000033 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994 		JBrowse link
G Fcgr2a Fc gamma receptor 2A involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1861924 (PMID:8769481), (PMID:9743367)		 GO_Central
RGD		 PMID:8769481 PMID:9743367 GO_REF:0000033 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Fcgr2al1 Fc gamma receptor 2A like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:83,302,874...83,315,744
Ensembl chr13:83,280,790...83,484,920 		JBrowse link
G Fcgr2b Fc gamma receptor 2B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (PMID:11711607), (PMID:27670158), (PMID:28652325) RGD PMID:11711607 PMID:27670158 PMID:28652325 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921 		JBrowse link
G Ighe immunoglobulin heavy constant epsilon involved_in ISO (PMID:30956175) RGD PMID:30956175
G Ighg1 immunoglobulin heavy constant gamma 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:11711607)
(PMID:9743367)		 RGD PMID:9743367 PMID:11711607 Ensembl chr 6:132,389,370...132,393,397 JBrowse link
G LOC134481532 low affinity immunoglobulin gamma Fc region receptor III involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
negative regulation of type I hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2b Fc gamma receptor 2B acts_upstream_of_or_within ISO MGI:1857166 (PMID:8552190) RGD PMID:8552190 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
negative regulation of type IV hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il20rb interleukin 20 receptor subunit beta acts_upstream_of_or_within ISO MGI:3830304 (PMID:19124723) RGD PMID:19124723 NCBI chr 8:100,979,085...101,010,829
Ensembl chr 8:100,980,383...101,009,942 		JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO MGI:1857246 (PMID:9645617) RGD PMID:9645617 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628 		JBrowse link
positive regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,870,939...4,910,183 JBrowse link
positive regulation of hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (MGI:1346262|PMID:10520991) RGD PMID:10520991 MGI:1346262 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309 		JBrowse link
positive regulation of type I hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase IMP RGD PMID:22228807 RGD:11040701 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Fcer1a Fc epsilon receptor Ia acts_upstream_of_or_within ISO MGI:2383982 (PMID:8252632) RGD PMID:8252632 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351 		JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:2384004 (PMID:14764707) RGD PMID:14764707 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fcgr2a Fc gamma receptor 2A acts_upstream_of_or_within ISO MGI:1861924 (PMID:8552190), (PMID:8769481), (PMID:9743367) RGD PMID:8552190 PMID:8769481 PMID:9743367 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 acts_upstream_of_or_within ISO (PMID:6952213), (PMID:8552190), (PMID:9743367) RGD PMID:6952213 PMID:8552190 PMID:9743367 Ensembl chr 6:132,389,370...132,393,397 JBrowse link
positive regulation of type IIa hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1861799 (PMID:11901193)		 Ensembl
RGD		 PMID:11901193 GO_REF:0000107 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:1857165|MGI:2384004 (PMID:11901193), (PMID:11911824), (PMID:8976192) RGD PMID:8976192 PMID:11901193 PMID:11911824 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fcgr1a Fc gamma receptor 1A acts_upstream_of_or_within ISO MGI:2664927 (PMID:11911824) RGD PMID:11911824 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994 		JBrowse link
G Fcgr2a Fc gamma receptor 2A acts_upstream_of_or_within ISO MGI:1861924 (PMID:11911824), (PMID:9834201) RGD PMID:9834201 PMID:11911824 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 acts_upstream_of_or_within ISO (PMID:11901193), (PMID:9834201) RGD PMID:9834201 PMID:11901193 Ensembl chr 6:132,389,370...132,393,397 JBrowse link
positive regulation of type III hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase IMP RGD PMID:22228807 RGD:11040701 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:1857165 (PMID:8976192) RGD PMID:8976192 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fcgr1a Fc gamma receptor 1A acts_upstream_of_or_within ISO MGI:2679238 (PMID:11911823) RGD PMID:11911823 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994 		JBrowse link
G Fcgr2a Fc gamma receptor 2A acts_upstream_of_or_within ISO MGI:1861924 (PMID:8769481) RGD PMID:8769481 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
positive regulation of type IV hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zp3 zona pellucida glycoprotein 3 involved_in ISO
ISS
IEA		 (PMID:15579591)
(MGI:4943411|PMID:15579591)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:15579591 GO_REF:0000024 GO_REF:0000107 MGI:4943411 NCBI chr12:20,690,547...20,697,513
Ensembl chr12:20,690,547...20,697,513 		JBrowse link
regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2a Fc gamma receptor 2A IMP RGD PMID:16482158 RGD:2293335 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
regulation of type IV hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fut7 fucosyltransferase 7 involved_in ISO (MGI:2387961|PMID:11535629) RGD PMID:11535629 MGI:2387961 NCBI chr 3:8,237,687...8,242,273
Ensembl chr 3:8,239,384...8,242,260 		JBrowse link
type I hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc epsilon receptor Ia involved_in ISO (PMID:8551243) RGD PMID:8551243 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351 		JBrowse link
G Ighe immunoglobulin heavy constant epsilon involved_in ISO (PMID:8551243) RGD PMID:8551243
type IV hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephb6 Eph receptor B6 acts_upstream_of_or_within ISO MGI:3522020 (PMID:15599401) RGD PMID:15599401 NCBI chr 4:70,491,973...70,507,230
Ensembl chr 4:70,491,973...70,507,230 		JBrowse link
G Gata3 GATA binding protein 3 IEP RGD PMID:16336837 RGD:2314191 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    immune system process 2822
      immune response 1927
        inflammatory response to antigenic stimulus 96
          acute inflammatory response to antigenic stimulus 41
            hypersensitivity 21
              negative regulation of hypersensitivity + 3
              positive regulation of hypersensitivity + 10
              regulation of hypersensitivity + 14
              type I hypersensitivity + 7
              type II hypersensitivity + 11
              type III hypersensitivity + 4
              type IV hypersensitivity + 6
Path 2
Term Annotations click to browse term
  biological_process 19694
    response to stimulus 10517
      response to stress 4181
        defense response 1864
          inflammatory response 858
            inflammatory response to antigenic stimulus 96
              acute inflammatory response to antigenic stimulus 41
                hypersensitivity 21
                  negative regulation of hypersensitivity + 3
                  positive regulation of hypersensitivity + 10
                  regulation of hypersensitivity + 14
                  type I hypersensitivity + 7
                  type II hypersensitivity + 11
                  type III hypersensitivity + 4
                  type IV hypersensitivity + 6
paths to the root