RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Experimental Autoimmune Uveoretinitis
Accession: DOID:9006642
browse the term
Definition: An experimental animal model use for the study of retinitis combined with uveitis. It is commonly induced with interphotoreceptor retinoid-binding protein (IRBP) (relapsing EAU) or retinal S-Antigen (monophasic EAU).
Synonyms: exact_synonym: EAU
primary_id: RDO:9000024
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Ace2
angiotensin converting enzyme 2
treatment
ISO
human gene in a mouse model
RGD
PMID:25228068
RGD:40818264
NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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C3
complement C3
ISO
RGD
PMID:16143328
RGD:7401262
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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Ccl2
C-C motif chemokine ligand 2
ISO
mRNA:increased expression:eye:
RGD
PMID:12605265
RGD:8661671
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccr2
C-C motif chemokine receptor 2
ISO
mRNA:increased expression:eye:
RGD
PMID:12605265
RGD:8661671
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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Cd40lg
CD40 ligand
treatment
ISO
RGD
PMID:15972638
RGD:8547777
NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306
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Cfb
complement factor B
treatment
ISO IMP
RGD
PMID:20806290 PMID:21216963
RGD:7411717 , RGD:7411732
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
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Icam1
intercellular adhesion molecule 1
treatment
IMP
RGD
PMID:7909311
RGD:8547706
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Ifng
interferon gamma
IEP
mRNA,protein:increased expression:eye:
RGD
PMID:1572694
RGD:8142388
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Il10
interleukin 10
treatment
ISO IDA
RGD
PMID:22629453 PMID:21296818 PMID:15240742 PMID:11359436
RGD:7364830 , RGD:7364849 , RGD:7365075 , RGD:7365084
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il2
interleukin 2
disease_progression
ISO IEP
mRNA:increased expression:uvea:
RGD
PMID:7929845 PMID:7803357
RGD:8662951 , RGD:8662946
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Il4
interleukin 4
disease_progression
IEP
mRNA:increased expression:uvea:
RGD
PMID:7803357
RGD:8662946
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Stat3
signal transducer and activator of transcription 3
ISO
RGD
PMID:18424728
RGD:8694299
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Tnfrsf1a
TNF receptor superfamily member 1A
ISO
RGD
PMID:19635911
RGD:8661744
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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