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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:crescentic glomerulonephritis
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Accession:DOID:13139 term browser browse the term
Definition:A syndrome of the kidney that is characterized by a rapid loss of renal function involving severe injury to the kidneys' glomeruli, with many of the glomeruli containing characteristic glomerular crescents (crescent-shaped scars).
Synonyms:exact_synonym: RPGN
 related_synonym: NCGN;   necrotizing crescentic glomerulonephritis
 xref: NCI:C128143;   NCI:C35444
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
crescentic glomerulonephritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL2 C-C motif chemokine ligand 2 treatment ISO RGD PMID:8903512 PMID:17314328 RGD:8549743, RGD:8549770 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 IEP
ISO		 associated with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis RGD PMID:18846416 PMID:17898087 RGD:7241813, RGD:2307059 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CD40 CD40 molecule ISO RGD PMID:14569091 RGD:7248599 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand treatment ISO RGD PMID:14569091 RGD:7248599 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CSF1R colony stimulating factor 1 receptor treatment ISO RGD PMID:23408165 RGD:151665815 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372 		JBrowse link
G FCGR2A Fc gamma receptor IIa ISO DNA:CNV:3'UTR: RGD PMID:16482158 RGD:2293335 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013 		JBrowse link
G IL1B interleukin 1 beta ISO RGD PMID:19959716 RGD:7175502 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment IDA human protein in a rat model RGD PMID:7637259 RGD:8551712 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:18443593 RGD:2293336 NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622 		JBrowse link
G MMP12 matrix metallopeptidase 12 ISO RGD PMID:20488952 PMID:12626598 RGD:2325762, RGD:737630 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982 		JBrowse link
G MMP3 matrix metallopeptidase 3 ISO RGD PMID:11095647 RGD:7241255 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO protein:increased expression:renal cortex (rat) RGD PMID:16046515 RGD:2313720 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO RGD PMID:21403644 RGD:7245940 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 ISO RGD PMID:21985369 RGD:7243976 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139 		JBrowse link
G TLR9 toll like receptor 9 severity ISO RGD PMID:20847283 RGD:7246899 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 35773
    syndrome 18145
      crescentic glomerulonephritis 15
Path 2
Term Annotations click to browse term
  disease 35773
    disease of anatomical entity 32516
      Urogenital Diseases 6481
        urinary system disease 2974
          kidney disease 2704
            nephritis 438
              glomerulonephritis 383
                acute proliferative glomerulonephritis 15
                  crescentic glomerulonephritis 15
paths to the root