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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:isoscutellarein
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Accession:CHEBI:6059 term browser browse the term
Definition:A tetrahydroxyflavone that is apigenin with an extra hydroxy group at position 8.
Synonyms:exact_synonym: 5,7,8-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
 related_synonym: 8-Hydroxyapigenin;   Formula=C15H10O6;   InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)12-6-10(18)13-9(17)5-11(19)14(20)15(13)21-12/h1-6,16-17,19-20H;   InChIKey=NXHQVROAKYDSNW-UHFFFAOYSA-N;   SMILES=Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(O)c2o1
 xref: CAS:41440-05-5;   KEGG:C10097;   KNApSAcK:C00003848;   LIPID_MAPS_instance:LMPK12111361
 xref_mesh: MESH:C000722867
 xref: PMID:1814628;   PMID:22146136;   Reaxys:304400


show annotations for term's descendants           Sort by:
isoscutellarein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO isoscutellarein results in increased expression of ADIPOQ protein CTD PMID:30445784 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Lep leptin decreases expression ISO isoscutellarein results in decreased expression of LEP protein CTD PMID:30445784 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Rbp4 retinol binding protein 4 decreases expression ISO isoscutellarein results in decreased expression of RBP4 protein CTD PMID:30445784 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO isoscutellarein results in increased expression of SLC2A4 protein CTD PMID:30445784 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Tnf tumor necrosis factor decreases expression ISO isoscutellarein results in decreased expression of TNF protein CTD PMID:30445784 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      biological role 19812
        biochemical role 19522
          metabolite 19509
            isoscutellarein 5
              isoscutellarein glycoside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            organic molecule 19684
                              organic cyclic compound 19496
                                organic heterocyclic compound 18874
                                  oxacycle 17889
                                    benzopyran 11958
                                      1-benzopyran 11710
                                        flavonoid 7193
                                          anthoxanthin 4542
                                            flavones 4542
                                              hydroxyflavone 4520
                                                trihydroxyflavone 429
                                                  apigenin 292
                                                    isoscutellarein 5
                                                      isoscutellarein glycoside 0
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