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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1,2-dilauroyl-sn-glycero-3-phosphocholine(1+)
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Accession:CHEBI:60273 term browser browse the term
Definition:A A 1,2-diacyl-sn-glycero-3-phosphocholine(1+) that is the dilauroyl diester of phosphatidiylcholine.
Synonyms:related_synonym: 1,2-Dilauroyl-sn-glycero-3-phosphocholine;   1,2-Dilauroylphosphatidylcholine;   1,2-Dlpc;   Dilauroyl lecithin;   Dilauroylphosphatidylcholine;   Dilaurylphosphatidylcholine;   Formula=C32H65NO8P;   InChI=1S/C32H64NO8P/c1-6-8-10-12-14-16-18-20-22-24-31(34)38-28-30(29-40-42(36,37)39-27-26-33(3,4)5)41-32(35)25-23-21-19-17-15-13-11-9-7-2/h30H,6-29H2,1-5H3/p+1/t30-/m1/s1;   InChIKey=IJFVSSZAOYLHEE-SSEXGKCCSA-O;   SMILES=CCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCC
 xref: CAS:18285-71-7
 xref_mesh: MESH:C015153
 xref: PMID:3512434
 cyclic_relationship: is_conjugate_acid_of CHEBI:65211


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1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP
ISO		 [1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A2 protein
[1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A4 protein		 CTD PMID:1627548 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 increases expression ISO 1,2-dilauroylphosphatidylcholine results in increased expression of NR5A2 CTD PMID:24459144 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
G Pon1 paraoxonase 1 increases activity ISO 1,2-dilauroylphosphatidylcholine results in increased activity of PON1 protein CTD PMID:12963475 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19834
    role 19810
      application 19653
        pharmaceutical 19494
          drug 19494
            1,2-diacyl-sn-glycero-3-phosphocholine(1+) 3
              1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19834
    subatomic particle 19832
      composite particle 19832
        hadron 19832
          baryon 19832
            nucleon 19832
              atomic nucleus 19832
                atom 19832
                  main group element atom 19782
                    main group molecular entity 19782
                      s-block molecular entity 19620
                        hydrogen molecular entity 19607
                          hydrides 19113
                            inorganic hydride 18117
                              pnictogen hydride 18106
                                nitrogen hydride 18013
                                  ammonium 8311
                                    ammonium ion derivative 8306
                                      quaternary ammonium ion 5275
                                        phosphatidylcholine(1+) 5
                                          1,2-diacyl-sn-glycero-3-phosphocholine(1+) 3
                                            1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) 3
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