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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phenoxyphenol
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Accession:CHEBI:39262 term browser browse the term
Synonyms:related_synonym: Formula=C12H10O2



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4-phenoxyphenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects binding ISO 4-phenoxyphenol binds to CYP1A2 protein CTD PMID:32278787 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
fenoxycarb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity
ISO fenoxycarb inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]
fenoxycarb results in decreased activity of ABCB1 protein
CTD PMID:21783720 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Ache acetylcholinesterase decreases activity EXP fenoxycarb results in decreased activity of ACHE protein CTD PMID:14644616 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions EXP fenoxycarb results in decreased activity of [CHRNA3 protein binds to CHRNB2 protein]; fenoxycarb results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein] CTD PMID:14644616 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP fenoxycarb results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; fenoxycarb results in decreased activity of [CHRNA4 protein binds to CHRNB4 protein] CTD PMID:14644616 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP fenoxycarb results in decreased activity of [CHRNA3 protein binds to CHRNB2 protein]; fenoxycarb results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14644616 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions EXP fenoxycarb results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein]; fenoxycarb results in decreased activity of [CHRNA4 protein binds to CHRNB4 protein] CTD PMID:14644616 NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO fenoxycarb results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
pyriproxyfen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases expression ISO pyriproxyfen metabolite results in increased expression of CASP3 protein CTD PMID:34289950 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Dlx2 distal-less homeobox 2 increases expression
multiple interactions
ISO pyriproxyfen metabolite results in increased expression of DLX2 mRNA
[pyriproxyfen metabolite co-treated with Triiodothyronine] results in increased expression of DLX2 mRNA
CTD PMID:34289950 NCBI chr 3:56,370,238...56,373,581
Ensembl chr 3:56,370,483...56,373,597
JBrowse link
G Fasn fatty acid synthase increases expression
multiple interactions
ISO pyriproxyfen metabolite results in increased expression of FASN mRNA
[pyriproxyfen metabolite co-treated with Triiodothyronine] results in increased expression of FASN mRNA
CTD PMID:34289950 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Msi1 musashi RNA-binding protein 1 multiple interactions
increases expression
ISO [pyriproxyfen metabolite co-treated with Triiodothyronine] results in increased expression of MSI1 mRNA
pyriproxyfen metabolite results in increased expression of MSI1 mRNA; pyriproxyfen metabolite results in increased expression of MSI1 protein
CTD PMID:34289950 NCBI chr12:41,158,301...41,251,134
Ensembl chr12:41,158,599...41,191,076
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO pyriproxyfen results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Sox10 SRY-box transcription factor 10 decreases expression
multiple interactions
ISO pyriproxyfen metabolite results in decreased expression of SOX10 mRNA
[pyriproxyfen metabolite co-treated with Triiodothyronine] results in decreased expression of SOX10 mRNA
CTD PMID:34289950 NCBI chr 7:110,725,274...110,734,651
Ensembl chr 7:110,725,274...110,735,544
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    chemical entity 19836
      molecular entity 19836
        polyatomic entity 19794
          heteroatomic molecular entity 19751
            hydroxides 19330
              organic hydroxy compound 18953
                phenols 18636
                  phenoxyphenol 13
                    2-phenoxyphenol 0
                    3-phenoxyphenol + 0
                    4-phenoxyphenol + 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            heteroorganic entity 19488
                              organochalcogen compound 19251
                                organooxygen compound 19168
                                  ether 17280
                                    aromatic ether 16526
                                      diphenyl ether 2808
                                        phenoxyphenol 13
                                          2-phenoxyphenol 0
                                          3-phenoxyphenol + 0
                                          4-phenoxyphenol + 13
paths to the root