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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb1a
Name: ATP binding cassette subfamily B member 1A
Acc ID: CHEBI:5009
Term: fenoxycarb
Definition: A carbamate ester that is the O-ethyl carbamate of 2-(4-phenoxyphenoxy)ethylamine.
Chemical ID: MESH:C052034
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb1adecreases activityISOABCB1 (Homo sapiens)6480464CTDfenoxycarb results in decreased activity of ABCB1 proteinPMID:21783720
Abcb1amultiple interactionsISOABCB1 (Homo sapiens)6480464CTDfenoxycarb inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]PMID:21783720
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