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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Arg-Gly-Asp
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Accession:CHEBI:158966 term browser browse the term
Synonyms:exact_synonym: (2S)-2-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]butanedioic acid
 related_synonym: Formula=C12H22N6O6;   InChI=1S/C12H22N6O6/c13-6(2-1-3-16-12(14)15)10(22)17-5-8(19)18-7(11(23)24)4-9(20)21/h6-7H,1-5,13H2,(H,17,22)(H,18,19)(H,20,21)(H,23,24)(H4,14,15,16)/t6-,7-/m0/s1;   InChIKey=IYMAXBFPHPZYIK-BQBZGAKWSA-N;   SMILES=O=C(NCC(=O)N[C@@H](CC(O)=O)C(O)=O)[C@@H](N)CCCN=C(N)N
 xref: CAS:99896-85-2;   Chemspider:94603
 xref_mesh: MESH:C047981


show annotations for term's descendants           Sort by:
Arg-Gly-Asp term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP arginyl-glycyl-aspartic acid inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of AKT1 protein] CTD PMID:14627993 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Itga5 integrin subunit alpha 5 multiple interactions ISO arginyl-glycyl-aspartic acid inhibits the reaction [Resveratrol binds to [ITGA5 protein binds to ITGB3 protein]] CTD PMID:16790523 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837 		JBrowse link
G Itgav integrin subunit alpha V multiple interactions ISO arginyl-glycyl-aspartic acid inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]] CTD PMID:15213856 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb1 integrin subunit beta 1 affects binding ISO arginyl-glycyl-aspartic acid binds to ITGB1 protein CTD PMID:37027338 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO arginyl-glycyl-aspartic acid inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; arginyl-glycyl-aspartic acid inhibits the reaction [Resveratrol binds to [ITGA5 protein binds to ITGB3 protein]] CTD PMID:15213856 PMID:16790523 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP		 arginyl-glycyl-aspartic acid inhibits the reaction [Resveratrol results in increased phosphorylation of MAPK1 protein]
arginyl-glycyl-aspartic acid inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; arginyl-glycyl-aspartic acid inhibits the reaction [Resveratrol results in increased phosphorylation of MAPK1 protein]		 CTD PMID:14627993 PMID:16790523 PMID:17984113 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP		 arginyl-glycyl-aspartic acid inhibits the reaction [Resveratrol results in increased phosphorylation of MAPK3 protein]
arginyl-glycyl-aspartic acid inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; arginyl-glycyl-aspartic acid inhibits the reaction [Resveratrol results in increased phosphorylation of MAPK3 protein]		 CTD PMID:14627993 PMID:16790523 PMID:17984113 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO arginyl-glycyl-aspartic acid results in increased expression of MMP1 CTD PMID:15547672 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Myl9 myosin light chain 9 affects phosphorylation ISO arginyl-glycyl-aspartic acid affects the phosphorylation of MYL9 protein CTD PMID:37027338 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO arginyl-glycyl-aspartic acid results in decreased expression of POU5F1 protein CTD PMID:37027338 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Tfap2a transcription factor AP-2 alpha decreases expression ISO arginyl-glycyl-aspartic acid results in decreased expression of TFAP2A protein CTD PMID:37027338 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression ISO arginyl-glycyl-aspartic acid results in decreased expression of TIMP1 CTD PMID:15547672 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO arginyl-glycyl-aspartic acid inhibits the reaction [Resveratrol results in increased phosphorylation of TP53 protein] CTD PMID:16790523 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    chemical entity 19836
      group 19795
        organic group 18962
          amino-acid residue 11129
            peptide 11129
              oligopeptide 1341
                Arg-Gly-Asp 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            heteroorganic entity 19488
                              organochalcogen compound 19251
                                organooxygen compound 19168
                                  carbon oxoacid 18637
                                    carboxylic acid 18634
                                      carboacyl group 17696
                                        univalent carboacyl group 17696
                                          carbamoyl group 17546
                                            carboxamide 17546
                                              peptide 11129
                                                oligopeptide 1341
                                                  Arg-Gly-Asp 13
paths to the root