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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:eudesmane sesquiterpenoid
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Accession:CHEBI:62508 term browser browse the term
Definition:Any sesquiterpenoid having a eudesmane skeleton.
Synonyms:related_synonym: eudesmane sesquiterpenoids


show annotations for term's descendants           Sort by:
beta-eudesmol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased cleavage of and results in increased activity of CASP1 protein] CTD PMID:30148989 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of CXCL2 protein] CTD PMID:30148989 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of ICAM1 protein] CTD PMID:30148989 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of IL1B protein] CTD PMID:30148989 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of TNF protein] CTD PMID:30148989 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO beta-eudesmol inhibits the reaction [OVAL protein results in increased expression of TSLP protein] CTD PMID:30148989 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
isoalantolactone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases expression ISO isoalantolactone results in increased expression of CASP3 protein modified form CTD PMID:29800641 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 increases cleavage
multiple interactions
increases expression		 ISO isoalantolactone results in increased cleavage of CASP7 protein
Acetylcysteine inhibits the reaction [isoalantolactone results in increased expression of CASP7 protein modified form]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [isoalantolactone results in increased expression of CASP7 protein modified form]; TNFRSF10B protein promotes the reaction [isoalantolactone results in increased expression of CASP7 protein modified form]		 CTD PMID:29800641 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression
increases cleavage
multiple interactions		 ISO isoalantolactone results in increased expression of PARP1 protein modified form
isoalantolactone results in increased cleavage of PARP1 protein
Acetylcysteine inhibits the reaction [isoalantolactone results in increased expression of PARP1 protein modified form]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [isoalantolactone results in increased expression of PARP1 protein modified form]; TNFRSF10B protein promotes the reaction [isoalantolactone results in increased expression of PARP1 protein modified form]		 CTD PMID:29800641 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      atom 19806
        nonmetal atom 19744
          carbon atom 19702
            organic molecular entity 19702
              isoprenoid 14057
                terpenoid 13755
                  sesquiterpenoid 3270
                    eudesmane sesquiterpenoid 9
                      (+)-4,11-Eudesmadien-3-one 0
                      (+)-4-epi-cryptomeridiol 0
                      (+)-Intermedeol 0
                      (-)-Eudesm-3-ene-6alpha-acetoxy-7alpha-ol 0
                      (-)-Methyl selina-3,11-dien-14-oate 0
                      (-)-chrysanthemol 0
                      (1R,2R,4aS,5R,8aR)-2-isopropyl-4a-methyl-8-methylenedecahydronaphthalene-1,5-diol 0
                      (1S,4S,4aS,6R,8aR)-decahydro-1,4-dimethyl-6-(prop-1-en-2-yl)naphthalen-1-ol 0
                      (1S,5S,6S,7S,10S)-10alpha-eudesm-4(15)-ene-1alpha,6alpha-diol 0
                      (1beta,4alpha,5beta,6alpha,7beta,10beta)-1,6,11-Eudesmanetriol 0
                      (5beta,6alpha)-6,11-Dihydroxyeudesmane 0
                      (7beta)-3-Eudesmene-7,11-diol (7b-hydroxy-7-epi-a-eudesmol)) 0
                      1,2-Dehydro-alpha-cyperone 0
                      10-Epijunenol 0
                      10-epi-gamma-eudesmol 0
                      10-epi-juneol 0
                      11-eudesmene-1alpha,6beta-diol 0
                      1alpha,6beta,11-eudesmanetriol 0
                      1beta,4beta,7alpha-trihydroxyeudesmane 0
                      1beta,6alpha-dihydroxy-4(14)-eudesmene 0
                      1beta-hydroxy-6,7alpha-dihydroxyeudesm-4(15)-ene 0
                      2-(7,8-dihydroxy-4a,8-dimethyl-1,2,3,4,5,6,7,8a-octahydronaphthalen-2-yl)prop-2-enoic acid 0
                      2-(8-Hydroxy-4a,8-dimethyldecahydro-2-naphthalenyl)acrylic acid 0
                      2-[(1S,2S,4aR,8aS)-1-hydroxy-4a-methyl-8-methylidene-1,2,3,4,5,6,7,8a-octahydronaphthalen-2-yl]prop-2-enoic acid 0
                      2-[(2S,4aR,8aS)-2-hydroxy-4a-methyl-8-methylidene-3,4,5,6,7,8a-hexahydro-1H-naphthalen-2-yl]prop-2-enoic acid 0
                      2-[(2r,4as,8s,8as)-8-[2-[(4as,7r,8ar)-7-(1-carboxyethenyl)-1-hydroxy-4a-methyl-2-oxo-6,7,8,8a-tetrahydro-5h-naphthalen-1-yl]ethyl]-4a-methyl-7-oxo-1,2,3,4,8,8a-hexahydronaphthalen-2-yl]prop-2-enoic acid 0
                      2-[4a-methyl-8-methylidene-4-(3-methylpentanoyloxy)-1,2,3,4,5,6,7,8a-octahydronaphthalen-2-yl]prop-2-enoic acid 0
                      3,5,11-Eudesmatriene 0
                      3-Oxo-1,4,11(13)-eudesmatrien-12-oic acid 0
                      4(15)-eudesmene-1beta,7alpha-diol 0
                      4,6-Diene-1beta,14-dihydroxyeudesma-3-one 0
                      4alpha,5alpha-diacetoxy-9alpha-benzoyloxy-7betaH-eudesman-1beta,2beta,11, 14-tetraol 0
                      4alpha,8alpha-dihydroxyeudesman-11-en-1-one 0
                      5-bromo-1-isopropyl-2,5a-dimethyl-decahydro-cyclopropa[a]inden-2-ol 0
                      6,12-Dihydroxy-1,4-eudesmadien-3-one 0
                      6alpha-Carissanol 0
                      7-(2-hydroxypropan-2-yl)-1,4a-dimethyl-decahydronaphthalen-1-ol 0
                      7-Hydroxycostal 0
                      7-Hydroxycostol 0
                      7-epi-alpha-eudesmol 0
                      7-epi-ent-eudesmane-5,11-diol 0
                      Acolamone 0
                      Acorusdiol 0
                      Acorusnol 0
                      Arundinol A 0
                      Arundinol B 0
                      Arundinol C 0
                      Atractyloside C 0
                      Atractyloside G 0
                      Auberganol 0
                      Aubergenone 0
                      Cryptomeridiol 11-rhamnoside 0
                      Cycloeudesmol 0
                      Cyperol 0
                      Dictyophorine B 0
                      Dictyosporin C 0
                      Dictyosporin D 0
                      Encelin 0
                      Ent-4(15)-eudesmen-11-ol-1-one 0
                      Ent-4(15)-eudesmen-1alpha,11-diol 0
                      Ent-4(15)-eudesmen-5,7-diol-1-one 0
                      Ent-alpha-Cyperone 0
                      Eudesma-5,11-diene 0
                      Eudesobovatol A 0
                      Eudesobovatol B 0
                      Eunicea sesquiterpenoid 2 0
                      Farinosin 0
                      Granilin 0
                      Ilicic acid 0
                      Isoacolamone 0
                      Isocyperol 0
                      Isointermedeol 0
                      Isopterocarpolone 0
                      Ivalin 0
                      Kandenol A 0
                      Kandenol B 0
                      Kandenol C 0
                      Kandenol D 0
                      Kikkanol A 0
                      Kikkanol B 0
                      Kikkanol C 0
                      Lairdinol A 0
                      Maali-3-en-8alpha-ol 0
                      Maaliane-4alpha, 8alpha, 9alpha-triol 0
                      Maaliane-5alpha, 8alpha, 9alpha-triol 0
                      Macrocarpal E 0
                      Macrocarpal H 0
                      Macrocarpal I 0
                      N-[(1s,2s,8s,8as)-8-hydroxy-7-\{(2s)-1-[(2r)-2-(methoxymethyl)-1-pyrrolidinyl]-1-oxo-2-propanyl\}-1,4a-dimethyldecahydro-2-naphthalenyl]-5-pyrimidinecarboxamide 0
                      NCGC00169093-01 0
                      Penicieudesmol A 0
                      Penicieudesmol B 0
                      Penicieudesmol C 0
                      Penicieudesmol D 0
                      Penicieudesmol E 0
                      Penicieudesmol F 0
                      Penicieudesmol G 0
                      Pterocarpol 0
                      Quadrangolin A 0
                      Rhombidiol 0
                      Rhombitriol 0
                      Rosifoliol 0
                      Samboginone, (rel)- 0
                      Scopararane C 0
                      Selinan 0
                      Teucdiol E 0
                      Teucdiol F 0
                      Teucrenone 0
                      Thomimarine A 0
                      Thomimarine B 0
                      Thomimarine D 0
                      Thomimarine E 0
                      [5-Formyl-4,8-dihydroxy-3-(3-methoxy-3-oxoprop-1-en-2-yl)-8a-methyl-2,3,4,4a,5,6,7,8-octahydro-1H-naphthalen-2-yl] 3,4-dihydroxy-2-methylidenebutanoate 0
                      [7-(2-hydroxypropan-2-yl)-4a-methyl-1-methylidene-2,3,4,5,6,7,8,8a-octahydronaphthalen-2-yl] acetate 0
                      alpha-Carissanol 0
                      alpha-Cyperol 0
                      alpha-Cyperone 0
                      alpha-Rotunol 0
                      alpha-epi-7-epi-5-Eudesmol 0
                      alpha-eudesmol 0
                      beta-Costic acid 0
                      beta-Costol 0
                      beta-eudesmol 6
                      corymbolone 0
                      cryptomeridiol 0
                      cyperusol C 0
                      dihydroagarofuran + 0
                      gamma-Eudesmol rhamnoside 0
                      gamma-eudesmol 0
                      isoalantolactone 3
                      methyl 2-[1,3,8-trihydroxy-8-(hydroxymethyl)-4a-methyl-5-oxo-2,3,4,6,7,8a-hexahydro-1H-naphthalen-2-yl]prop-2-enoate 0
                      mucrolidin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    main group molecular entity 19756
                      s-block molecular entity 19595
                        hydrogen molecular entity 19582
                          hydrides 19095
                            organic hydride 18669
                              organic fundamental parent 18669
                                hydrocarbon 18415
                                  terpene 14057
                                    terpenoid 13755
                                      sesquiterpenoid 3270
                                        eudesmane sesquiterpenoid 9
                                          (+)-4,11-Eudesmadien-3-one 0
                                          (+)-4-epi-cryptomeridiol 0
                                          (+)-Intermedeol 0
                                          (-)-Eudesm-3-ene-6alpha-acetoxy-7alpha-ol 0
                                          (-)-Methyl selina-3,11-dien-14-oate 0
                                          (-)-chrysanthemol 0
                                          (1R,2R,4aS,5R,8aR)-2-isopropyl-4a-methyl-8-methylenedecahydronaphthalene-1,5-diol 0
                                          (1S,4S,4aS,6R,8aR)-decahydro-1,4-dimethyl-6-(prop-1-en-2-yl)naphthalen-1-ol 0
                                          (1S,5S,6S,7S,10S)-10alpha-eudesm-4(15)-ene-1alpha,6alpha-diol 0
                                          (1beta,4alpha,5beta,6alpha,7beta,10beta)-1,6,11-Eudesmanetriol 0
                                          (5beta,6alpha)-6,11-Dihydroxyeudesmane 0
                                          (7beta)-3-Eudesmene-7,11-diol (7b-hydroxy-7-epi-a-eudesmol)) 0
                                          1,2-Dehydro-alpha-cyperone 0
                                          10-Epijunenol 0
                                          10-epi-gamma-eudesmol 0
                                          10-epi-juneol 0
                                          11-eudesmene-1alpha,6beta-diol 0
                                          1alpha,6beta,11-eudesmanetriol 0
                                          1beta,4beta,7alpha-trihydroxyeudesmane 0
                                          1beta,6alpha-dihydroxy-4(14)-eudesmene 0
                                          1beta-hydroxy-6,7alpha-dihydroxyeudesm-4(15)-ene 0
                                          2-(7,8-dihydroxy-4a,8-dimethyl-1,2,3,4,5,6,7,8a-octahydronaphthalen-2-yl)prop-2-enoic acid 0
                                          2-(8-Hydroxy-4a,8-dimethyldecahydro-2-naphthalenyl)acrylic acid 0
                                          2-[(1S,2S,4aR,8aS)-1-hydroxy-4a-methyl-8-methylidene-1,2,3,4,5,6,7,8a-octahydronaphthalen-2-yl]prop-2-enoic acid 0
                                          2-[(2S,4aR,8aS)-2-hydroxy-4a-methyl-8-methylidene-3,4,5,6,7,8a-hexahydro-1H-naphthalen-2-yl]prop-2-enoic acid 0
                                          2-[(2r,4as,8s,8as)-8-[2-[(4as,7r,8ar)-7-(1-carboxyethenyl)-1-hydroxy-4a-methyl-2-oxo-6,7,8,8a-tetrahydro-5h-naphthalen-1-yl]ethyl]-4a-methyl-7-oxo-1,2,3,4,8,8a-hexahydronaphthalen-2-yl]prop-2-enoic acid 0
                                          2-[4a-methyl-8-methylidene-4-(3-methylpentanoyloxy)-1,2,3,4,5,6,7,8a-octahydronaphthalen-2-yl]prop-2-enoic acid 0
                                          3,5,11-Eudesmatriene 0
                                          3-Oxo-1,4,11(13)-eudesmatrien-12-oic acid 0
                                          4(15)-eudesmene-1beta,7alpha-diol 0
                                          4,6-Diene-1beta,14-dihydroxyeudesma-3-one 0
                                          4alpha,5alpha-diacetoxy-9alpha-benzoyloxy-7betaH-eudesman-1beta,2beta,11, 14-tetraol 0
                                          4alpha,8alpha-dihydroxyeudesman-11-en-1-one 0
                                          5-bromo-1-isopropyl-2,5a-dimethyl-decahydro-cyclopropa[a]inden-2-ol 0
                                          6,12-Dihydroxy-1,4-eudesmadien-3-one 0
                                          6alpha-Carissanol 0
                                          7-(2-hydroxypropan-2-yl)-1,4a-dimethyl-decahydronaphthalen-1-ol 0
                                          7-Hydroxycostal 0
                                          7-Hydroxycostol 0
                                          7-epi-alpha-eudesmol 0
                                          7-epi-ent-eudesmane-5,11-diol 0
                                          Acolamone 0
                                          Acorusdiol 0
                                          Acorusnol 0
                                          Arundinol A 0
                                          Arundinol B 0
                                          Arundinol C 0
                                          Atractyloside C 0
                                          Atractyloside G 0
                                          Auberganol 0
                                          Aubergenone 0
                                          Cryptomeridiol 11-rhamnoside 0
                                          Cycloeudesmol 0
                                          Cyperol 0
                                          Dictyophorine B 0
                                          Dictyosporin C 0
                                          Dictyosporin D 0
                                          Encelin 0
                                          Ent-4(15)-eudesmen-11-ol-1-one 0
                                          Ent-4(15)-eudesmen-1alpha,11-diol 0
                                          Ent-4(15)-eudesmen-5,7-diol-1-one 0
                                          Ent-alpha-Cyperone 0
                                          Eudesma-5,11-diene 0
                                          Eudesobovatol A 0
                                          Eudesobovatol B 0
                                          Eunicea sesquiterpenoid 2 0
                                          Farinosin 0
                                          Granilin 0
                                          Ilicic acid 0
                                          Isoacolamone 0
                                          Isocyperol 0
                                          Isointermedeol 0
                                          Isopterocarpolone 0
                                          Ivalin 0
                                          Kandenol A 0
                                          Kandenol B 0
                                          Kandenol C 0
                                          Kandenol D 0
                                          Kikkanol A 0
                                          Kikkanol B 0
                                          Kikkanol C 0
                                          Lairdinol A 0
                                          Maali-3-en-8alpha-ol 0
                                          Maaliane-4alpha, 8alpha, 9alpha-triol 0
                                          Maaliane-5alpha, 8alpha, 9alpha-triol 0
                                          Macrocarpal E 0
                                          Macrocarpal H 0
                                          Macrocarpal I 0
                                          N-[(1s,2s,8s,8as)-8-hydroxy-7-\{(2s)-1-[(2r)-2-(methoxymethyl)-1-pyrrolidinyl]-1-oxo-2-propanyl\}-1,4a-dimethyldecahydro-2-naphthalenyl]-5-pyrimidinecarboxamide 0
                                          NCGC00169093-01 0
                                          Penicieudesmol A 0
                                          Penicieudesmol B 0
                                          Penicieudesmol C 0
                                          Penicieudesmol D 0
                                          Penicieudesmol E 0
                                          Penicieudesmol F 0
                                          Penicieudesmol G 0
                                          Pterocarpol 0
                                          Quadrangolin A 0
                                          Rhombidiol 0
                                          Rhombitriol 0
                                          Rosifoliol 0
                                          Samboginone, (rel)- 0
                                          Scopararane C 0
                                          Selinan 0
                                          Teucdiol E 0
                                          Teucdiol F 0
                                          Teucrenone 0
                                          Thomimarine A 0
                                          Thomimarine B 0
                                          Thomimarine D 0
                                          Thomimarine E 0
                                          [5-Formyl-4,8-dihydroxy-3-(3-methoxy-3-oxoprop-1-en-2-yl)-8a-methyl-2,3,4,4a,5,6,7,8-octahydro-1H-naphthalen-2-yl] 3,4-dihydroxy-2-methylidenebutanoate 0
                                          [7-(2-hydroxypropan-2-yl)-4a-methyl-1-methylidene-2,3,4,5,6,7,8,8a-octahydronaphthalen-2-yl] acetate 0
                                          alpha-Carissanol 0
                                          alpha-Cyperol 0
                                          alpha-Cyperone 0
                                          alpha-Rotunol 0
                                          alpha-epi-7-epi-5-Eudesmol 0
                                          alpha-eudesmol 0
                                          beta-Costic acid 0
                                          beta-Costol 0
                                          beta-eudesmol 6
                                          corymbolone 0
                                          cryptomeridiol 0
                                          cyperusol C 0
                                          dihydroagarofuran + 0
                                          gamma-Eudesmol rhamnoside 0
                                          gamma-eudesmol 0
                                          isoalantolactone 3
                                          methyl 2-[1,3,8-trihydroxy-8-(hydroxymethyl)-4a-methyl-5-oxo-2,3,4,6,7,8a-hexahydro-1H-naphthalen-2-yl]prop-2-enoate 0
                                          mucrolidin 0
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