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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:benzofuran
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Accession:CHEBI:36790 term browser browse the term
Synonyms:related_synonym: Formula=C8H6O
 xref: DrugBank:DB04179


show annotations for term's descendants           Sort by:
1-benzofuran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsm1 acyl-CoA synthetase medium-chain family member 1 affects expression
increases expression		 ISO benzofuran affects the expression of ACSM1 mRNA
benzofuran results in increased expression of ACSM1 mRNA		 CTD PMID:17114358 PMID:17311802 NCBI chr 1:173,985,715...174,020,565
Ensembl chr 1:173,984,672...174,025,495 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions EXP benzofuran binds to and results in increased activity of AHR protein CTD PMID:21431309 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ces1d carboxylesterase 1D affects expression
increases expression		 ISO benzofuran affects the expression of CES1 mRNA
benzofuran results in increased expression of CES1 mRNA		 CTD PMID:17114358 PMID:17311802 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO benzofuran analog results in decreased activity of CYP19A1 protein CTD PMID:15968818 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO benzofuran analog results in decreased activity of CYP1A2 protein CTD PMID:15916432 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
affects expression		 ISO benzofuran results in increased expression of EPHX1 mRNA
benzofuran affects the expression of EPHX1 mRNA		 CTD PMID:17114358 PMID:17311802 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects expression ISO benzofuran affects the expression of GSTM1 mRNA CTD PMID:17114358 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma affects expression ISO benzofuran affects the expression of IKBKG mRNA CTD PMID:17114358 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 affects expression ISO benzofuran affects the expression of ITIH1 mRNA CTD PMID:17114358 NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO benzofuran results in increased activity of NFE2L2 protein CTD PMID:30114225 PMID:30203046 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO benzofuran results in increased expression of NQO1 mRNA CTD PMID:17311802 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO benzofuran results in increased activity of NR1I3 protein CTD PMID:30203046 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Pls1 plastin 1 affects expression ISO benzofuran affects the expression of PLS1 mRNA CTD PMID:17114358 NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
increases activity		 ISO benzofuran results in increased expression of PPARA mRNA
benzofuran results in increased activity of PPARA protein		 CTD PMID:25689681 PMID:30203046 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Snhg11 small nucleolar RNA host gene 11 affects expression ISO benzofuran affects the expression of SNHG11 mRNA CTD PMID:17114358 NCBI chr 3:147,031,367...147,037,043 JBrowse link
G Stat5b signal transducer and activator of transcription 5B increases activity ISO benzofuran results in increased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Ttc39a tetratricopeptide repeat domain 39A affects expression ISO benzofuran affects the expression of TTC39A mRNA CTD PMID:17114358 NCBI chr 5:124,165,102...124,204,740
Ensembl chr 5:124,151,760...124,204,973 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase affects expression ISO benzofuran affects the expression of UGDH mRNA CTD PMID:17114358 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354 		JBrowse link
licocoumarone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A multiple interactions ISO licocoumarone binds to and results in decreased activity of DYRK1A protein CTD PMID:31838052 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase decreases expression ISO licocoumarone results in decreased expression of MET protein CTD PMID:31838052 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      molecular entity 19806
        mancude ring 11165
          organic mancude parent 11165
            mancude organic heterocyclic parent 11165
              mancude organic heterobicyclic parent 8316
                benzofuran 20
                  1-benzofuran + 20
                  2-benzofuran 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            organic molecule 19655
                              organic cyclic compound 19468
                                organic heterocyclic compound 18848
                                  organic heteropolycyclic compound 18278
                                    organic heterobicyclic compound 17216
                                      mancude organic heterobicyclic parent 8316
                                        benzofuran 20
                                          1-benzofuran + 20
                                          2-benzofuran 0
paths to the root