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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:adipic acid
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Accession:CHEBI:30832 term browser browse the term
Definition:An alpha,omega-dicarboxylic acid that is the 1,4-dicarboxy derivative of butane.
Synonyms:exact_synonym: hexanedioic acid
 related_synonym: 1,4-butanedicarboxylic acid;   1,6-hexanedioic acid;   Adipinsaeure;   E 355;   E355;   Formula=C6H10O4;   INS No. 355;   InChI=1S/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10);   InChIKey=WNLRTRBMVRJNCN-UHFFFAOYSA-N;   SMILES=OC(=O)CCCCC(O)=O;   adipinic acid
 alt_id: CHEBI:22268;   CHEBI:2489
 xref: Beilstein:1209788;   CAS:124-04-9;   Drug_Central:3474;   FAO/WHO_standards:174;   Gmelin:3166;   HMDB:HMDB0000448;   KEGG:C06104;   KEGG:D08839;   KNApSAcK:C00001178;   LIPID_MAPS_instance:LMFA01170048
 xref_mesh: MESH:C029900
 xref: MetaCyc:ADIPATE;   PDBeChem:0L1;   PMID:22770225;   PMID:24491734;   PMID:24895214;   Reaxys:1209788;   Wikipedia:Adipic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:30833


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adipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO adipic acid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]]; adipic acid inhibits the reaction [SLC22A6 protein results in increased transport of 2-amino-3-(2-amino-2-carboxyethylsulfanyl-mercuricsulfanyl)-propionic acid analog] CTD PMID:12606766 PMID:15284288 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173 		JBrowse link
2-oxoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of alpha-ketoadipic acid CTD PMID:20567778 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
bis(2-ethylhexyl) adipate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor decreases expression EXP dioctyl adipate results in decreased expression of GRN mRNA CTD PMID:16493179 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases activity ISO dioctyl adipate results in decreased activity of HSD11B1 protein CTD PMID:16184081 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 decreases expression EXP dioctyl adipate results in decreased expression of NOLC1 mRNA CTD PMID:16493179 NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      application 19661
        food additive 16128
          food acidity regulator 11945
            adipic acid 5
              2,3,5-trihydroxy-4-phosphonooxyadipic acid 0
              2,4-dichloro-3-oxoadipic acid 0
              2-amino-3-oxoadipic acid 0
              2-chloro-3-oxoadipic acid 0
              2-hydroxy-3-oxoadipic acid 0
              2-hydroxyadipic acid + 0
              2-oxoadipic acid 1
              3-aminoadipic acid + 0
              3-methyladipic acid 0
              3-oxoadipic acid + 0
              4-hydroxy-4-methyl-2-oxoadipic acid 0
              5-adenylyl-2-aminoadipic acid 0
              6-(2-hydroxyethoxy)-6-oxohexanoic acid 0
              L-2-aminoadipic acid + 0
              O-adipoylcarnitine + 0
              adipoyl-CoA + 0
              bis(2-ethylhexyl) adipate 3
              di-(N-succinimidyl) adipate 0
              hexanedioyl group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            heteroorganic entity 19492
                              organochalcogen compound 19255
                                organooxygen compound 19172
                                  carbon oxoacid 18641
                                    carboxylic acid 18638
                                      monocarboxylic acid 18008
                                        fatty acid 16809
                                          fatty acid derivative 8969
                                            dicarboxylic fatty acid 2650
                                              adipic acid 5
                                                2,3,5-trihydroxy-4-phosphonooxyadipic acid 0
                                                2,4-dichloro-3-oxoadipic acid 0
                                                2-amino-3-oxoadipic acid 0
                                                2-chloro-3-oxoadipic acid 0
                                                2-hydroxy-3-oxoadipic acid 0
                                                2-hydroxyadipic acid + 0
                                                2-oxoadipic acid 1
                                                3-aminoadipic acid + 0
                                                3-methyladipic acid 0
                                                3-oxoadipic acid + 0
                                                4-hydroxy-4-methyl-2-oxoadipic acid 0
                                                5-adenylyl-2-aminoadipic acid 0
                                                6-(2-hydroxyethoxy)-6-oxohexanoic acid 0
                                                L-2-aminoadipic acid + 0
                                                O-adipoylcarnitine + 0
                                                adipoyl-CoA + 0
                                                bis(2-ethylhexyl) adipate 3
                                                di-(N-succinimidyl) adipate 0
                                                hexanedioyl group 0
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