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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions increases transport |
ISO |
ABCB1A gene mutant form affects the transport of and results in increased abundance of huperzine A Elacridar inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of huperzine A] |
CTD |
PMID:28587984 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Ache |
acetylcholinesterase |
decreases activity multiple interactions |
ISO EXP |
huperzine A results in decreased activity of ACHE protein [huperzine A co-treated with tetramethylpyrazine] results in decreased activity of ACHE protein ALB protein affects the reaction [huperzine A results in decreased activity of ACHE protein]; huperzine A inhibits the reaction [ACHE protein results in increased hydrolysis of Butyrylthiocholine] huperzine A binds to and results in decreased activity of ACHE protein |
CTD |
PMID:15135892 PMID:15652380 PMID:17309523 PMID:18572153 PMID:18573242 PMID:19345205 PMID:20624417 PMID:22407886 PMID:26902639 PMID:27238725 More...
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NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Alb |
albumin |
multiple interactions |
ISO |
ALB protein affects the reaction [huperzine A results in decreased activity of ACHE protein] |
CTD |
PMID:26902639 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
increases metabolic processing |
EXP |
CYP1A2 protein results in increased metabolism of huperzine A |
CTD |
PMID:12586202 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
increases metabolic processing |
EXP |
CYP3A2 protein results in increased metabolism of huperzine A |
CTD |
PMID:12586202 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp3a23-3a1 |
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 |
increases metabolic processing |
EXP |
CYP3A23-3A1 protein results in increased metabolism of huperzine A |
CTD |
PMID:12586202 |
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NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP |
huperzine A inhibits the reaction [Acetic Acid results in increased expression of IL1B protein] |
CTD |
PMID:23810507 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
huperzine A inhibits the reaction [Acetic Acid results in increased expression of RELA protein] |
CTD |
PMID:23810507 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP |
huperzine A inhibits the reaction [Acetic Acid results in increased expression of TNF protein] |
CTD |
PMID:23810507 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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