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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Alpinetin
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Accession:CHEBI:229049 term browser browse the term
Synonyms:exact_synonym: (2S)-7-hydroxy-5-methoxy-2-phenyl-2,3-dihydrochromen-4-one
 related_synonym: Formula=C16H14O4;   InChI=1S/C16H14O4/c1-19-14-7-11(17)8-15-16(14)12(18)9-13(20-15)10-5-3-2-4-6-10/h2-8,13,17H,9H2,1H3/t13-/m0/s1;   InChIKey=QQQCWVDPMPFUGF-ZDUSSCGKSA-N;   SMILES=O1[C@@H](CC(=O)C2=C1C=C(O)C=C2OC)C3=CC=CC=C3
 xref: Chemspider:135938
 xref_mesh: MESH:C436748



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Alpinetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases activity
multiple interactions
ISO alpinetin results in increased activity of ACHE protein
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [alpinetin results in increased activity of ACHE protein]
CTD PMID:31034797 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions ISO AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; AHR protein affects the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; AHR protein affects the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]; alpinetin promotes the reaction [TNF promotes the reaction [AHR protein binds to SUV39H1 protein]] CTD PMID:31676321 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of CYP1A1 protein]] CTD PMID:31676321 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO
EXP
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; [alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG5 mRNA]]; alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG5 mRNA]; Leucine inhibits the reaction [alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG5 mRNA]]
CTD PMID:31676321 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287
JBrowse link
G Atg7 autophagy related 7 multiple interactions EXP
ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG7 mRNA]]; alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG7 mRNA]; Leucine inhibits the reaction [alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG7 mRNA]]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; [alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]
CTD PMID:31676321 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575
JBrowse link
G Becn1 beclin 1, autophagy related multiple interactions ISO
EXP
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; [alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in increased expression of BECN1 protein]; [Dextran Sulfate co-treated with alpinetin] results in increased expression of BECN1 protein; Leucine inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in increased expression of BECN1 protein]
CTD PMID:31676321 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]; Chloroquine inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]; Leucine inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]]
CTD PMID:31676321 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cldn7 claudin 7 multiple interactions ISO alpinetin inhibits the reaction [TNF protein results in decreased expression of CLDN7 mRNA] CTD PMID:31676321 NCBI chr11:69,855,605...69,858,712
Ensembl chr11:69,855,605...69,858,711
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO alpinetin inhibits the reaction [TNF protein results in decreased expression of CYP1A1 protein]; ARNT protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of CYP1A1 protein]] CTD PMID:31676321 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions EXP
ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in increased expression of and results in increased lipidation of MAP1LC3B protein]; [Dextran Sulfate co-treated with alpinetin] results in increased expression of and results in increased lipidation of MAP1LC3B protein; Leucine inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in increased expression of and results in increased lipidation of MAP1LC3B protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]; AHR protein affects the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]; alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]; TSC2 protein affects the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]
CTD PMID:31676321 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Leucine inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]] CTD PMID:31676321 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Ocln occludin multiple interactions ISO alpinetin inhibits the reaction [TNF protein results in decreased expression of OCLN mRNA] CTD PMID:31676321 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Rps6 ribosomal protein S6 multiple interactions ISO
EXP
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6 protein]
CTD PMID:31676321 NCBI chr 4:86,772,336...86,775,604
Ensembl chr 4:86,772,897...86,775,649
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 multiple interactions EXP
ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6KB1 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6KB1 protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]
CTD PMID:31676321 NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions EXP
ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein]; [Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein; Leucine inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; [alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]
CTD PMID:31676321 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Suv39h1 suppressor of variegation 3-9 1 multiple interactions ISO
EXP
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; [TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein; AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; AHR protein affects the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; alpinetin promotes the reaction [TNF promotes the reaction [AHR protein binds to SUV39H1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased expression of SUV39H1 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased expression of SUV39H1 protein]
CTD PMID:31676321 NCBI chr  X:7,927,401...7,940,994
Ensembl chr  X:7,927,410...7,940,999
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]; [alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein; [alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA; [alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA; [alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein; [TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; AHR protein affects the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; AHR protein affects the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]; alpinetin inhibits the reaction [TNF protein results in decreased expression of CLDN7 mRNA]; alpinetin inhibits the reaction [TNF protein results in decreased expression of CYP1A1 protein]; alpinetin inhibits the reaction [TNF protein results in decreased expression of OCLN mRNA]; alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]; alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 protein]; alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]; alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]; alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]; alpinetin promotes the reaction [TNF promotes the reaction [AHR protein binds to SUV39H1 protein]]; alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]; ARNT protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of CYP1A1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; Chloroquine inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; TSC2 protein affects the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]] CTD PMID:31676321 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tsc2 TSC complex subunit 2 multiple interactions ISO
EXP
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]]; AHR protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]]; alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 mRNA]; alpinetin inhibits the reaction [TNF protein results in decreased expression of TSC2 protein]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG5 mRNA]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of ATG7 mRNA]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in increased expression of BECN1 protein]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein]]; TSC2 protein affects the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]]; TSC2 protein affects the reaction [alpinetin promotes the reaction [TNF protein results in increased expression of and results in increased lipidation of MAP1LC3B protein]]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in decreased expression of TSC2 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in decreased expression of TSC2 protein]
CTD PMID:31676321 NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604
JBrowse link

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  CHEBI ontology 22210
    chemical entity 22209
      atom 22202
        nonmetal atom 22086
          carbon atom 21861
            organic molecular entity 21861
              flavonoids 11800
                Alpinetin 18
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  CHEBI ontology 22210
    subatomic particle 22202
      composite particle 22202
        hadron 22202
          baryon 22202
            nucleon 22202
              atomic nucleus 22202
                atom 22202
                  main group element atom 22136
                    p-block element atom 22136
                      carbon group element atom 21936
                        carbon atom 21861
                          organic molecular entity 21861
                            heteroorganic entity 21517
                              organochalcogen compound 21005
                                organooxygen compound 20846
                                  ether 18198
                                    Alpinetin 18
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