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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736485
Species: Mus musculus
RGD Object: Gene
Symbol: Sqstm1
Name: sequestosome 1
Acc ID: CHEBI:229049
Term: Alpinetin
Definition: null
Chemical ID: MESH:C436748
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sqstm1multiple interactionsEXP 6480464CTD2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein]; [Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein; Leucine inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein]PMID:31676321
Sqstm1multiple interactionsISOSQSTM1 (Homo sapiens)6480464CTD2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; [alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein; AHR protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]; TSC2 protein affects the reaction [[alpinetin co-treated with TNF protein] results in decreased expression of SQSTM1 protein]PMID:31676321
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