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Pathways

Strain: SHR-Tg(EEF1A1-Cd36)106Ipcv

Symbol: SHR-Tg(EEF1A1-Cd36)106Ipcv
Strain: SHR-Tg(EEF1A1-Cd36)106
Substrain: Ipcv
RGD ID: 2302151
Citation ID: RRID:RGD_2302151
Ontology ID: RS:0001690
Alleles: Cd36
Also Known As: SHR/Ola-TgN(Ef1aCd36)106Ipcv;SHR-TG106; SHR-Tg(Ef1a-Cd36)106Ipcv
Type: transgenic
Available Source: Not Available
Origination: Czech Academy of Sciences, Prague, Czech Republic
Description: Generated by microinjecting SHR/OlaIpcv zygotes with wild type Cd36 DNA from WKY cloned into Invitrogen pEF1/V5-HisA vector (with human EEF1A1 promoter)
Last Known Status: Unknown





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Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Transgenic expression of CD36 in the spontaneously hypertensive rat is associated with amelioration of metabolic disturbances but has no effect on hypertension. Pravenec M, etal., Physiol Res. 2003;52(6):681-8.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease No effect was noticed in blood pressure as compared to parent SHR/OlaIpcv 1600636
strain_phys_biochem Transgene is expressed in kidney, liver, white adipose tissue, and skeletal muscles 1600636

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-08-01 SHR-Tg(EEF1A1-Cd36)106Ipcv    SHR-Tg(Ef1a-Cd36)106Ipcv    Symbol and/or name change 68913 APPROVED