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Strain Registration

Strain: ACI.FHH-(D1Mit18-D1Mit8)(D14Mit11-D14Hmgc14b)(D14Rat65-D14Rat90)/Eur

Symbol: ACI.FHH-(D1Mit18-D1Mit8)(D14Mit11-D14Hmgc14b)(D14Rat65-D14Rat90)/Eur
Strain: ACI.FHH-(D1Mit18-D1Mit8)(D14Mit11-D14Hmgc14b)(D14Rat65-D14Rat90)
Substrain: Eur
RGD ID: 1598801
Citation ID: RRID:RGD_1598801
Ontology ID: RS:0001162
Also Known As: ACI.FHH-(D1Mit18-D1Mit8)(D14Mit11-D14Hmgc14b)(D14Rat65-D14Rat90)/Eur; Rf-1B+4; ACI.FHH-(D1Mit18-D1Mit8)(D14Mit11-D14Hmgc14b)(D14Rat65-D14Rat90)/Eur
Type: congenic
Available Source: Not Available
Origination: Department of Pediatric Surgery, Erasmus Medical Center, Rotterdam, Netherlands
Description: Triple congenic strain which was generated using the speed congenic strategy by backcrossing ACI/Eur and FHH/Eur parental strains. Rf1 QTL region of chr 1 and Rf4 QTL region of chr 14 are introgressed in this strain.
Last Known Status: Unknown





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
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References

References - curated
# Reference Title Reference Citation
1. RGD Strain RSO annotation pipeline RGD Automated Pipelines
2. Absence of an interaction between the Rf-1 and Rf-5 QTLs influencing susceptibility to renal damage in rats. van Dijk SJ, etal., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12.

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other Renal damage susceptibility is increased to other congenic strains which have the Rf-1 region showing a synergistic interaction between QTL Rf1 and Rf4. 1582571
strain_phys_biochem These have impaired renal autoregulation. 1582571