Slc6a3 Strain Search Result - Rat Genome Database

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5 records found for search term Slc6a3

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RGD ID	Symbol	Name	Origin	Source	Type	Annotations	Match
9588572	LE-Tg(Slc6a3-icre)1Ottc		The transgene contains BAC transgenic using rat DAT promoter to express Cre recombinase in dopaminergic neurons	Optogenetics and Transgenic Technology Core, Rat Resource and Research Center	transgenic	1	symbol
9588576	LE-Tg(Slc6a3-icre)5Ottc		The transgene contains BAC transgenic using rat DAT promoter to express Cre recombinase in dopaminergic neurons	Optogenetics and Transgenic Technology Core	transgenic	1	symbol
9588578	LE-Tg(Slc6a3-icre)6Ottc		The transgene contains BAC transgenic using rat dopamine transporterSlc6a3 (DAT) promoter to express Cre recombinase in dopaminergic neurons	Optogenetics and Transgenic Technology Core, Rat Resource and Research Center	transgenic	1	symbol , origin
126925196	F344-Slc6a3^m1Span		This strain was identified in the N-ethyl-N-nitrosourea (ENU)-driven target-selected mutagenesis screen. A point mutation in the Slc6a3 (DAT) coding sequence (exon 3) with a T/G transversion at nucleotide position 471 was identified in a male rat. This nucleotid ... (more) e exchange leads to substitution of an asparagine amino acid residue by a lysine residue at position 157 (N157K) in the SLC6A3 (DAT) protein, which introduces new positive charge into the amino acid sequence.		mutant	1	symbol , origin
12905031	SD-Slc6a3^tm1(cre)Sage		This model expresses cre-recombinase under the control of the endogenous dopamine transporter promoter enabling specific expression in dopaminergic neurons. This model possesses a targeted insertion of (IRES)-cre immediately after the translational stop in the open reading frame of DAT. The DAT-Cre ... (more) rat is useful for applications requiring tissue specific expression, including optogenetics and breeding with transgenic floxed lines.	Horizon Discovery	mutant	1	symbol , old_strain_symbol