Kcnj1 Strain Search Result - Rat Genome Database

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9 records found for search term Kcnj1

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RGD ID	Symbol	Name	Origin	Source	Type	Annotations	Match
13782280	SS-Kcnj1^em1Kasu+/+		Zinc Finger Nuclease (ZFN) was utilized to knockout rat Kcnj1 function. ZFN constructs targeting the gene were designed and purchased from Sigma Aldrich (St. Louis, MO, USA). The targeting site sequence is CTCAAGTGACCATAGGTTACGgattcaGGTTTGTGAC (lower case repres ... (more) ents the ZFN cleavage site). Kcnj1 knockout founders were generated by microinjection of ZFN mRNAs into single-cell SS (from Harlan) rat embryos. The resulting mutation is 209 bp deletion from G225 to G433, leading to frameshift and premature termination of Kcnj1 protein. This strain is the wild type littermate from heterozygous cross.		mutant	1	symbol , origin
13782351	SS-Kcnj1^em1Kasu+/-		Zinc Finger Nuclease (ZFN) was utilized to knockout rat Kcnj1 function. ZFN constructs targeting the gene were designed and purchased from Sigma Aldrich (St. Louis, MO, USA). The targeting site sequence is TCAAGTGACCATAGGTTACGgattcaGGTTTGTGAC (lower case represe ... (more) nts the ZFN cleavage site). Kcnj1 knockout founders were generated by microinjection of ZFN mRNAs into single -cell SS (from Harlan) rat embryos. The resulting mutation is 209 bp deletion from G225 to G433, leading to frameshift and premature termination of Kcnj1 protein in homozygotes.		mutant	3	symbol , origin
13782353	SS-Kcnj1^em1Kasu-/-		Zinc Finger Nuclease (ZFN) was utilized to knockout rat Kcnj1 function. ZFN constructs targeting the gene were designed and purchased from Sigma Aldrich (St. Louis, MO, USA). The targeting site sequence is CTCAAGTGACCATAGGTTACGgattcaGGTTTGTGAC (lower case repres ... (more) ents the ZFN cleavage site). Kcnj1 knockout founders were generated by microinjection of ZFN mRNAs into single-cell SS (from Harlan) rat embryos. The resulting mutation is 209 bp deletion from G225 to G433, leading to frameshift and premature termination of Kcnj1 protein in homozygotes.		mutant	8	symbol , origin
10054408	SS-Kcnj10^em1Mcwi		CRISPR/Cas9 system was used to introduce a mutation in the Kcnj10 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 1-bp insertion in the Kcnj10 gene.	Contact MCW rat distribution at mcwcustomrats@mcw.edu	mutant	1	symbol , origin , old_strain_symbol
10054411	SS-Kcnj10^em3Mcwi		CRISPR/Cas9 system was used to introduce a mutation in the Kcnj10 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 3-bp deletion in the Kcnj10 gene.	Contact MCW rat distribution at mcwcustomrats@mcw.edu	mutant	1	symbol , origin , old_strain_symbol
6893385	SS-Kcnj11^em5Mcwi		This strain was produced by injecting ZFNs targeting the sequence CTACAGAGCCCAGGTAccgtacTCGGGAGAGGAGGGC into SS/JrHsdMcwi rat embryos. The resulting mutation is a 8-bp deletion in exon 1.		mutant	1	symbol , old_strain_symbol
6893384	SS-Kcnj11^em9Mcwi		This strain was produced by injecting ZFNs targeting the sequence CTACAGAGCCCAGGTAccgtacTCGGGAGAGGAGGGC into SS/JrHsdMcwi rat embryos. The resulting mutation is a 5-bp deletion in exon 1.		mutant	1	symbol , old_strain_symbol
13207497	SS-Kcnj13^em1Mcwi		CRISPR/Cas9 system was used to introduce a mutation in the Kcnj13 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 1-bp insertion of exon 2 in the Kcnj13 gene.	Contact MCW rat distribution at mcwcustomrats@mcw.edu	mutant	1	symbol , origin , old_strain_symbol
6893434	SS-Kcnj16^em1Mcwi		This strain was produced by injecting ZFNs targeting the sequence AGCTGCATCATAAACACCttcatcATTGGGGCAGCCTTGGCA into SS/JrHsdMcwi rat embryos. The resulting mutation is a 18-bp deletion in exon 1.		mutant	20	symbol , old_strain_symbol