Vwce (von Willebrand factor C and EGF domains) - Rat Genome Database

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Pathways
Gene: Vwce (von Willebrand factor C and EGF domains) Chinchilla lanigera
Analyze
Symbol: Vwce
Name: von Willebrand factor C and EGF domains
RGD ID: 9062428
Description: ASSOCIATED WITH Dwarfism (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555116,235,530 - 6,251,216 (+)Ensembl
ChiLan1.0NW_0049555116,235,934 - 6,251,186 (+)NCBIChiLan1.0ChiLan1.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View
Dwarfism  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (ISO)
nucleoplasm  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Vwce
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555116,235,530 - 6,251,216 (+)Ensembl
ChiLan1.0NW_0049555116,235,934 - 6,251,186 (+)NCBIChiLan1.0ChiLan1.0
VWCE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,258,286 - 61,295,316 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,255,672 - 61,295,334 (-)Ensemblhg38GRCh38
GRCh371161,025,758 - 61,062,788 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361160,782,334 - 60,819,364 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1158,361,797 - 58,398,795 (-)NCBICelera
Cytogenetic Map11q12.2NCBI
HuRef1157,353,677 - 57,390,704 (-)NCBIHuRef
CHM1_11160,908,797 - 60,945,827 (-)NCBICHM1_1
T2T-CHM13v2.01161,240,163 - 61,284,304 (-)NCBIT2T-CHM13v2.0
Vwce
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391910,611,582 - 10,643,577 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1910,611,577 - 10,643,577 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381910,634,218 - 10,666,213 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1910,634,213 - 10,666,213 (+)Ensemblmm10GRCm38
MGSCv371910,708,723 - 10,739,700 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361910,701,281 - 10,732,255 (+)NCBIMGSCv36mm8
Celera1911,330,208 - 11,363,207 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map196.87NCBI
Vwce
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,703,742 - 216,753,284 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1216,707,351 - 216,738,337 (+)EnsemblGRCr8
mRatBN7.21207,280,714 - 207,327,215 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1207,282,356 - 207,312,986 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1215,661,231 - 215,691,451 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,716,699 - 222,746,908 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01215,411,695 - 215,441,905 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1216,068,175 - 216,099,153 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1220,977,280 - 221,008,262 (+)NCBILyon_Normotensive
Lyon_Hypertensive1217,731,629 - 217,762,612 (+)NCBILyon_Hypertensive
F344_StmMcwi1215,958,430 - 215,989,409 (+)NCBIF344_StmMcwi
Rnor_6.01226,687,258 - 226,717,989 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1226,687,258 - 226,710,897 (+)Ensemblrn6Rnor6.0
Rnor_5.01233,754,512 - 233,782,663 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41213,124,884 - 213,159,508 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1204,775,961 - 204,805,797 (+)NCBICelera
RGSC_v3.11213,283,313 - 213,317,938 (+)NCBI
Cytogenetic Map1q43NCBI
VWCE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2962,425,179 - 62,463,320 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,468,839 - 63,510,991 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,557,167 - 56,596,311 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11159,922,172 - 59,959,747 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1159,922,172 - 59,959,747 (-)EnsemblpanPan2panpan1.1
VWCE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11855,099,193 - 55,125,412 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1855,102,452 - 55,126,040 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1853,671,715 - 53,697,876 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01856,146,988 - 56,173,137 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1856,147,011 - 56,173,210 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11855,207,508 - 55,231,098 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01854,826,983 - 54,852,997 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01855,707,716 - 55,733,842 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Vwce
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494711,628,907 - 11,656,837 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365811,748,511 - 1,770,648 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VWCE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl210,206,012 - 10,240,148 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1210,206,010 - 10,240,493 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.229,753,388 - 9,786,165 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VWCE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1112,546,241 - 12,583,963 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl112,547,220 - 12,583,577 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038109,924,936 - 109,963,341 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vwce
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624926897,139 - 908,514 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624926894,001 - 911,510 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Vwce
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1210,116,707 - 10,147,590 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000004710   ⟹   ENSCLAP00000004624
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555116,235,530 - 6,251,216 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000004711   ⟹   ENSCLAP00000004625
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555116,235,530 - 6,248,535 (+)Ensembl
RefSeq Acc Id: XM_005408169   ⟹   XP_005408226
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555116,235,934 - 6,251,186 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005408226 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000004624.1
  ENSCLAP00000004625.1
RefSeq Acc Id: XP_005408226   ⟸   XM_005408169
- Sequence:
Ensembl Acc Id: ENSCLAP00000004624   ⟸   ENSCLAT00000004710
Ensembl Acc Id: ENSCLAP00000004625   ⟸   ENSCLAT00000004711
Protein Domains
EGF-like   VWFC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003291 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000004710.1 UniProtKB/TrEMBL
  ENSCLAT00000004711.1 UniProtKB/TrEMBL
Gene3D-CATH 6.20.200.20 UniProtKB/TrEMBL
  Complement Module, domain 1 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro cEGF UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  NOTCH1_EGF-like UniProtKB/TrEMBL
  vWF_C/EGF_Fibrillin UniProtKB/TrEMBL
  VWF_dom UniProtKB/TrEMBL
NCBI Gene Vwce ENTREZGENE
PANTHER VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam cEGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  VWC UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  VWFC_1 UniProtKB/TrEMBL
  VWFC_2 UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  VWC UniProtKB/TrEMBL
  VWC_out UniProtKB/TrEMBL
Superfamily-SCOP FnI-like domain UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A8C2UTN5_CHILA UniProtKB/TrEMBL
  A0A8C2UX90_CHILA UniProtKB/TrEMBL