Faf2 (Fas associated factor family member 2) - Rat Genome Database

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Gene: Faf2 (Fas associated factor family member 2) Chinchilla lanigera
Analyze
Symbol: Faf2
Name: Fas associated factor family member 2
RGD ID: 8998861
Description: ENCODES a protein that exhibits lipase binding (ortholog); lipase inhibitor activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN ERAD pathway (ortholog); lipid droplet organization (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH Chromosome 5, Trisomy 5q (ortholog); Ehlers-Danlos syndrome dermatosparaxis type (ortholog); Marfanoid Mental Retardation Syndrome, Autosomal (ortholog); FOUND IN endoplasmic reticulum (ortholog); lipid droplet (ortholog); VCP-NPL4-UFD1 AAA ATPase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FAS-associated factor 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540828,737,279 - 28,797,564 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540828,737,597 - 28,797,143 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Faf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540828,737,279 - 28,797,564 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540828,737,597 - 28,797,143 (+)NCBIChiLan1.0ChiLan1.0
FAF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385176,448,385 - 176,510,074 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5176,447,628 - 176,510,074 (+)EnsemblGRCh38hg38GRCh38
GRCh375175,875,386 - 175,937,075 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365175,807,962 - 175,869,681 (+)NCBINCBI36Build 36hg18NCBI36
Celera5172,564,653 - 172,626,310 (-)NCBICelera
Cytogenetic Map5q35.2NCBI
HuRef5170,799,773 - 170,861,507 (+)NCBIHuRef
CHM1_15175,308,267 - 175,369,883 (+)NCBICHM1_1
T2T-CHM13v2.05176,992,793 - 177,054,650 (+)NCBIT2T-CHM13v2.0
Faf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391354,769,597 - 54,811,876 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1354,769,597 - 54,811,876 (+)EnsemblGRCm39 Ensembl
GRCm381354,621,784 - 54,664,063 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1354,621,784 - 54,664,063 (+)EnsemblGRCm38mm10GRCm38
MGSCv371354,723,145 - 54,765,424 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361354,631,441 - 54,673,685 (+)NCBIMGSCv36mm8
Celera1355,687,533 - 55,729,876 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1328.88NCBI
Faf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8179,952,329 - 9,994,596 (-)NCBIGRCr8
mRatBN7.2179,947,211 - 9,989,474 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl179,947,220 - 9,989,485 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx179,961,656 - 10,003,682 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01711,495,078 - 11,537,125 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0179,958,092 - 10,000,115 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01710,485,650 - 10,527,886 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1710,485,642 - 10,527,864 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01712,611,437 - 12,653,503 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41716,011,489 - 16,051,440 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11716,011,489 - 16,051,440 (-)NCBI
Celera1710,024,573 - 10,062,663 (-)NCBICelera
Cytogenetic Map17p14NCBI
FAF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24171,525,358 - 171,587,028 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15169,664,897 - 169,726,570 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05171,743,071 - 171,804,687 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15178,813,998 - 178,875,208 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5178,814,100 - 178,876,108 (+)Ensemblpanpan1.1panPan2
FAF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1436,819,754 - 36,890,901 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl436,822,735 - 36,890,839 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha436,768,219 - 36,858,914 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0437,167,583 - 37,258,767 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl437,185,639 - 37,258,704 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1436,993,390 - 37,084,488 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0437,181,225 - 37,271,902 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0437,689,358 - 37,780,696 (-)NCBIUU_Cfam_GSD_1.0
Faf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213121,685,230 - 121,747,712 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936597710,100 - 772,765 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936597710,168 - 772,455 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl281,401,859 - 81,454,262 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1281,401,852 - 81,454,272 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2283,006,522 - 83,055,934 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FAF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12378,421,558 - 78,515,671 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2378,456,545 - 78,516,245 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660759,587,142 - 9,648,555 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Faf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473313,608,360 - 13,674,175 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473313,608,993 - 13,674,200 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000020244   ⟹   ENSCLAP00000020051
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540828,737,279 - 28,797,564 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000020245   ⟹   ENSCLAP00000020052
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540828,768,047 - 28,790,410 (+)Ensembl
RefSeq Acc Id: XM_005376389   ⟹   XP_005376446
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540828,737,597 - 28,797,143 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005376446 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000020051
  ENSCLAP00000020051.1
  ENSCLAP00000020052.1
RefSeq Acc Id: XP_005376446   ⟸   XM_005376389
- UniProtKB: A0A8C2VZR3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000020051   ⟸   ENSCLAT00000020244
Ensembl Acc Id: ENSCLAP00000020052   ⟸   ENSCLAT00000020245
Protein Domains
UAS   UBX


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013738 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000020244 ENTREZGENE
  ENSCLAT00000020244.1 UniProtKB/TrEMBL
  ENSCLAT00000020245.1 UniProtKB/TrEMBL
Gene3D-CATH DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
  Glutaredoxin UniProtKB/TrEMBL
InterPro FAF1_2-like_UAS UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
  UAS UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/TrEMBL
  UBA_8 UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
  UBX_dom UniProtKB/TrEMBL
  UBX_domain-protein UniProtKB/TrEMBL
NCBI Gene Faf2 ENTREZGENE
PANTHER FAS-ASSOCIATED FACTOR 2 UniProtKB/TrEMBL
  FAS-ASSOCIATED PROTEIN UniProtKB/TrEMBL
Pfam FAF1 UniProtKB/TrEMBL
  UBA_8 UniProtKB/TrEMBL
  UBX UniProtKB/TrEMBL
PROSITE UBX UniProtKB/TrEMBL
SMART UAS UniProtKB/TrEMBL
Superfamily-SCOP SSF46934 UniProtKB/TrEMBL
  SSF52833 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A8C2VV98_CHILA UniProtKB/TrEMBL
  A0A8C2VZR3 ENTREZGENE, UniProtKB/TrEMBL