Kctd7 (potassium channel tetramerization domain containing 7) - Rat Genome Database

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Gene: Kctd7 (potassium channel tetramerization domain containing 7) Heterocephalus glaber
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Symbol: Kctd7
Name: potassium channel tetramerization domain containing 7
RGD ID: 18902503
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN intracellular glutamate homeostasis (ortholog); intracellular potassium ion homeostasis (ortholog); positive regulation of transporter activity (ortholog); ASSOCIATED WITH epilepsy (ortholog); generalized epilepsy (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BTB/POZ domain-containing protein KCTD7; potassium channel tetramerisation domain containing 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247408,598,309 - 8,609,696 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247408,588,339 - 8,609,541 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (IEA)
plasma membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Kctd7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247408,598,309 - 8,609,696 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247408,588,339 - 8,609,541 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
KCTD7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38766,628,881 - 66,643,229 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl766,628,881 - 66,649,067 (+)Ensemblhg38GRCh38
GRCh37766,093,868 - 66,108,216 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36765,731,380 - 65,743,252 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34765,538,094 - 65,549,967NCBI
Celera766,008,064 - 66,022,242 (-)NCBICelera
Cytogenetic Map7q11.21NCBI
HuRef762,278,875 - 62,293,196 (+)NCBIHuRef
CHM1_1766,189,128 - 66,203,476 (+)NCBICHM1_1
T2T-CHM13v2.0767,848,529 - 67,862,889 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2765,431,411 - 65,445,769 (+)NCBI
Kctd7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395130,166,814 - 130,183,960 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5130,173,702 - 130,184,647 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385130,137,978 - 130,155,119 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5130,144,861 - 130,155,806 (+)Ensemblmm10GRCm38
MGSCv375130,620,758 - 130,631,678 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365130,429,591 - 130,440,511 (+)NCBIMGSCv36mm8
Celera5127,151,737 - 127,162,650 (+)NCBICelera
Cytogenetic Map5G1.3NCBI
cM Map568.72NCBI
Kctd7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81232,157,141 - 32,168,463 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1232,159,297 - 32,168,292 (-)EnsemblGRCr8
mRatBN7.21226,520,969 - 26,532,327 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1226,523,142 - 26,532,138 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1227,671,087 - 27,680,095 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01228,281,596 - 28,290,609 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01227,343,186 - 27,352,200 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01230,024,080 - 30,033,357 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1230,024,081 - 30,033,357 (-)Ensemblrn6Rnor6.0
Rnor_5.01231,961,818 - 31,970,830 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41227,564,093 - 27,573,372 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1228,237,507 - 28,246,407 (-)NCBICelera
Cytogenetic Map12q12NCBI
Kctd7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554568,627,763 - 8,636,206 (+)Ensembl
ChiLan1.0NW_0049554568,627,763 - 8,637,882 (+)NCBIChiLan1.0ChiLan1.0
KCTD7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2681,942,145 - 81,988,301 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17130,269,315 - 130,328,801 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0759,392,366 - 59,435,993 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1773,687,965 - 73,697,728 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl773,687,952 - 73,697,728 (+)EnsemblpanPan2panpan1.1
KCTD7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha62,764,741 - 2,791,265 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.06869,955 - 896,567 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl6869,908 - 986,852 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.16804,950 - 831,471 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.06807,116 - 833,698 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.06978,947 - 1,005,464 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
KCTD7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl316,385,006 - 16,393,841 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1316,382,333 - 16,393,861 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2316,636,406 - 16,646,076 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCTD7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1282,255,817 - 2,276,616 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl282,256,743 - 2,271,099 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607014,356,688 - 14,370,912 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kctd7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11623,829,670 - 23,838,418 (-)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000026168   ⟹   ENSHGLP00000025939
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247408,598,309 - 8,609,696 (+)Ensembl
RefSeq Acc Id: XM_004839992   ⟹   XP_004840049
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247408,588,341 - 8,609,541 (+)NCBI
RefSeq Acc Id: XM_021254334   ⟹   XP_021109993
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247408,588,339 - 8,609,541 (+)NCBI
RefSeq Acc Id: XM_021254335   ⟹   XP_021109994
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247408,594,193 - 8,609,541 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004840049 (Get FASTA)   NCBI Sequence Viewer  
  XP_021109993 (Get FASTA)   NCBI Sequence Viewer  
  XP_021109994 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025939
GenBank Protein JAN97553 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021109993   ⟸   XM_021254334
- Peptide Label: isoform X1
- UniProtKB: A0AAX6SQ83 (UniProtKB/TrEMBL),   A0A0P6J2N6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840049   ⟸   XM_004839992
- Peptide Label: isoform X2
- UniProtKB: A0AAX6NZ01 (UniProtKB/TrEMBL),   A0A0P6J2N6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021109994   ⟸   XM_021254335
- Peptide Label: isoform X1
- UniProtKB: A0AAX6SQ83 (UniProtKB/TrEMBL),   A0A0P6J2N6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000025939   ⟸   ENSHGLT00000026168


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018461 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000026168 ENTREZGENE
Gene3D-CATH Potassium Channel Kv1.1, Chain A UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/TrEMBL
KEGG Report hgl:101712678 UniProtKB/TrEMBL
NCBI Gene Kctd7 ENTREZGENE
PANTHER BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD7 UniProtKB/TrEMBL
  POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/TrEMBL
  KCTD_C UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/TrEMBL
UniProt A0A0P6J2N6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NZ01 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SQ83 ENTREZGENE, UniProtKB/TrEMBL