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Gene: LIPT2 (lipoyl(octanoyl) transferase 2) Chlorocebus sabaeus

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Symbol:

LIPT2

Name:

lipoyl(octanoyl) transferase 2

RGD ID:

18457610

Description:

ENCODES a protein that exhibits acyltransferase activity (inferred); lipoyl(octanoyl) transferase activity (inferred); transferase activity (inferred); INVOLVED IN protein lipoylation (inferred); ASSOCIATED WITH cardiomyopathy (ortholog); ENCEPHALOPATHY, PROGRESSIVE, EARLY-ONSET, WITH BRAIN ATROPHY AND SPASTICITY (ortholog); Neonatal Severe Encephalopathy with Lactic Acidosis and Brain Abnormalities (ortholog); FOUND IN mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

lipoyl(octanoyl) transferase 2 (putative); octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial; putative lipoyltransferase 2, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	65,731,258 - 65,733,803 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	65,731,969 - 65,733,563 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666043	60,127,138 - 60,129,477 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cardiomyopathy (ISO)

ENCEPHALOPATHY, PROGRESSIVE, EARLY-ONSET, WITH BRAIN ATROPHY AND SPASTICITY (ISO)

Neonatal Severe Encephalopathy with Lactic Acidosis and Brain Abnormalities (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein lipoylation (IEA)

Cellular Component

mitochondrion (IEA)

Molecular Function

acyltransferase activity (IEA)

lipoyl(octanoyl) transferase activity (IEA)

protein binding (ISO)

transferase activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LIPT2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	65,731,258 - 65,733,803 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	65,731,969 - 65,733,563 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666043	60,127,138 - 60,129,477 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LIPT2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	74,490,519 - 74,493,724 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	74,490,519 - 74,493,724 (-)	Ensembl			hg38	GRCh38
GRCh37	11	74,201,564 - 74,204,769 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	73,879,846 - 73,885,491 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	11	71,509,689 - 71,511,520 (-)	NCBI		Celera
Cytogenetic Map	11	q13.4	NCBI
HuRef	11	70,498,934 - 70,500,765 (-)	NCBI		HuRef
CHM1_1	11	74,086,444 - 74,088,275 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	74,419,953 - 74,423,157 (-)	NCBI		T2T-CHM13v2.0

Lipt2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	99,808,484 - 99,810,138 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	99,808,484 - 99,810,572 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	100,159,277 - 100,160,931 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	100,159,277 - 100,161,365 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	107,307,787 - 107,309,441 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	100,033,360 - 100,035,448 (+)	NCBI		MGSCv36	mm8
Celera	7	100,493,861 - 100,495,452 (+)	NCBI		Celera
Cytogenetic Map	7	E2	NCBI
cM Map	7	54.33	NCBI

Lipt2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	163,916,695 - 163,919,022 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	163,916,695 - 163,919,022 (+)	Ensembl				GRCr8
mRatBN7.2	1	154,504,563 - 154,506,890 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	154,504,563 - 154,506,890 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	162,498,895 - 162,501,222 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	169,678,993 - 169,681,320 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	162,552,575 - 162,554,902 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	1	162,899,457 - 162,901,783 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	1	167,888,667 - 167,890,993 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	1	164,528,942 - 164,531,268 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	1	163,124,106 - 163,126,459 (+)	NCBI		F344_StmMcwi
Rnor_6.0	1	165,170,645 - 165,172,972 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	165,170,645 - 165,172,972 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	171,371,500 - 171,373,827 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	157,538,704 - 157,541,031 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	152,588,580 - 152,590,907 (+)	NCBI		Celera
RGSC_v3.1	1	157,616,972 - 157,618,123 (+)	NCBI
Cytogenetic Map	1	q32	NCBI

LIPT2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	75,432,112 - 75,435,568 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	76,476,506 - 76,479,945 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	69,564,555 - 69,566,759 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	72,869,834 - 72,872,050 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	72,869,834 - 72,872,050 (-)	Ensembl			panPan2	panpan1.1

LIPT2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	23,845,253 - 23,846,977 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	23,845,268 - 23,846,537 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	23,610,345 - 23,612,296 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	24,047,717 - 24,049,673 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	24,047,719 - 24,050,486 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	23,845,125 - 23,847,080 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	24,042,411 - 24,044,367 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	23,959,988 - 23,961,944 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Lipt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	61,897,441 - 61,899,473 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936498	3,497,053 - 3,499,169 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936498	3,497,424 - 3,499,131 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LIPT2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	8,838,102 - 8,840,765 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	8,838,375 - 8,840,607 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	10,001,252 - 10,003,211 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Lipt2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624817	2,573,479 - 2,575,259 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624817	2,573,459 - 2,575,259 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Lipt2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	98,454,984 - 98,456,502 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in LIPT2
54 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008020134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038005472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JBLKOC010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000002035 ⟹ ENSCSAP00000000364

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	1	65,731,969 - 65,733,563 (-)	Ensembl

RefSeq Acc Id:

XM_008020134 ⟹ XP_008018325

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	1	65,731,258 - 65,733,803 (-)	NCBI
Vero_WHO_p1.0	NW_023666043	60,127,138 - 60,129,477 (+)	NCBI

Sequence:

show sequence

CACCGCTGTATCAAGCGCCTAGGGCAGGGCCTGCAGAACATAGCAGGCACTAAATGCTGGTTGT
TGAATGAACGGAGGAGGCCGGCCTGCGCTGGGTCCTGGGATCACAAATCCCCCCTCCAGCTTTT
AACACGCACCTGGGAGCCGCGGCTTGGGGCGTGCCCCTGAGTCCCCGCCCCTCATACCACGCCC
CCAGGCCCAGGGAGAGGGCGGGGTCCCGCGGACGCAGCGGTGGGCACGATGCGGCCAGCCGCGG
TTCGGCTGGTGCGCCTGGGTCGTGTGCCGTACGCCGAGCTGCTGGGGCTGCAGGACCGCTGGCT
GCGGCGGCTACAGGCCGAGCCAGGCACTGAAGCCTCATCGGGGACTGAGGCGGGCGCGCTCCTG
CTCTGCGAGCCCGCGGGGCCCGTGTACACGGCCGGGCTGCGCGGCGGCCTGACGCCCGAGGAAA
CTGCGCGGCTACGGGCCTTGGGCGCCGAGGTGCACGTCACAGGCCGCGGTGGCCTGGCCACCTT
CCACGGCCCGGGCCAGCTGCTTTGCCACCCGGTACTCGACCTGCGGCGTCTCGGTCTGCGCTTG
CGCATGCACGTAGCGGCGCTGGAGGCGTGCGCCGTGCGCCTGTGCGAGCTCCAGGGCCTGCAGG
ACGCCCGCGCGCGGTCCCCGCCCTACACCGGCGTCTGGCTGGACGATCGCAAGATCTGCGCGAT
CGGAGTCCGCTGTGGAAGGCACATCACGTCCCACGGCCTGGCTCTCAACTGCTCTACGGACCTC
ACGTGGTTTGAGCACATTGTGCCCTGTGGACTGGTTGGGACAGGCGTCACTTCCTTGAGTAAGG
AGCTCCAGAGACACGTCACCGTGAATGAAGTAATGCCACCTTTCCTTGTGGCCTTTAAGGAGAT
CTACAAGTGCACACTGATCTCAGAGGACAGCCCTGACTGAAGAGTACTCATAACAGCGAGGATG
CTCCTGCCTTGGGAAGCACGAAGCCTAACTTGAGTCACCTACTGAAACACAGATTTTAGACCTG
GCGTATCATTCACTGATCATGAAACTAAGGACATACCATGAGCTCTGAGCCACTGTTTTAATAT
GTATCCTGTTTTATTTATATCTAAATGTGACAACACTGAAAAGCAACACATGCTGTGTAAAACA
TTAGCACTACTATTGACAGCAGCGTCTCAGCTTAGAGAAATTCAGATGTCGTAGATTGTCATTT
CTCTATTGTTACTTCCTCAATACTGTGTTTAACTGAGCAGTTCTGGGCTCTAGTTCCCTCAATT
TTGTGGAAGTCAAATCTCTGAATGGCACAGGTGAAGGTGATATGATGTGGTGCTTTTTATTCTC
AAGAGACCTGGGTTCTTTCTGCAATAAAGGGAAAAGGGAAGAACCTTCAAAGGATAAAATGGAA
TCTTACCTTCCTGGGTTTGATTCCCCAAGTTTGATAATTTAGCAGTTTTTAGTTGGGTTACCCT
GAGCTAGGCCAAAGACTGGAGAAAGAACAAGAATAATTTCTCACACTGTACAAATGCCAAAGAT
AGAAGTGAGTTTTTTTATATGAGACCTGTAAGTTTGTAAGGCTGCGTATTATCTGTTACTGTGT
AACAAATCATCAAAACTTAGTGACTTAACAGTAAACATTAATTATCA

hide sequence

RefSeq Acc Id:

XM_038005472 ⟹ XP_037861400

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666043	60,127,138 - 60,128,656 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008018325	(Get FASTA)	NCBI Sequence Viewer
	XP_037861400	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000000364
	ENSCSAP00000000364.1

RefSeq Acc Id:	XP_008018325 ⟸ XM_008020134
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9QVH5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000000364 ⟸ ENSCSAT00000002035

RefSeq Acc Id:	XP_037861400 ⟸ XM_038005472
- Peptide Label:	isoform X2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000004004	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000002035.1	UniProtKB/TrEMBL
Gene3D-CATH	Bira Bifunctional Protein, Domain 2	UniProtKB/TrEMBL
InterPro	aa-tRNA-synth_II/BPL/LPL	UniProtKB/TrEMBL
	BPL_LPL_catalytic	UniProtKB/TrEMBL
	Octanoyltransferase	UniProtKB/TrEMBL
KEGG Report	csab:103248031	UniProtKB/TrEMBL
NCBI Gene	LIPT2	ENTREZGENE
PANTHER	LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED	UniProtKB/TrEMBL
	OCTANOYLTRANSFERASE	UniProtKB/TrEMBL
Pfam	LplA-B_cat	UniProtKB/TrEMBL
PIRSF	LPLase	UniProtKB/TrEMBL
PROSITE	BPL_LPL_CATALYTIC	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55681	UniProtKB/TrEMBL
UniProt	A0A0D9QVH5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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