Ccdc187 (coiled-coil domain containing 187) - Rat Genome Database

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Gene: Ccdc187 (coiled-coil domain containing 187) Rattus norvegicus
Analyze
Symbol: Ccdc187
Name: coiled-coil domain containing 187
RGD ID: 1565512
Description: Predicted to enable microtubule binding activity. Predicted to be involved in microtubule anchoring. Predicted to be located in centrosome. Orthologous to human CCDC187 (coiled-coil domain containing 187); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; C60 fullerene; methoxychlor.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: coiled-coil domain-containing protein 187; hypothetical protein LOC499759; LOC499759; RGD1565512; similar to hypothetical protein 4932418E24; uncharacterized protein LOC499759
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8329,468,292 - 29,525,002 (-)NCBIGRCr8
mRatBN7.239,070,192 - 9,127,001 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl39,070,185 - 9,126,946 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.033,724,656 - 3,747,440 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl33,724,656 - 3,747,440 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.039,086,793 - 9,115,518 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.434,451,179 - 4,473,859 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera33,918,377 - 3,941,161 (-)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centrosome  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Ccdc187
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8329,468,292 - 29,525,002 (-)NCBIGRCr8
mRatBN7.239,070,192 - 9,127,001 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl39,070,185 - 9,126,946 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.033,724,656 - 3,747,440 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl33,724,656 - 3,747,440 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.039,086,793 - 9,115,518 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.434,451,179 - 4,473,859 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera33,918,377 - 3,941,161 (-)NCBICelera
Cytogenetic Map3p13NCBI
CCDC187
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,249,973 - 136,306,901 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9136,249,973 - 136,306,901 (-)EnsemblGRCh38hg38GRCh38
GRCh379139,141,819 - 139,166,855 (-)NCBIGRCh37GRCh37hg19GRCh37
Celera9109,692,458 - 109,715,154 (-)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9108,637,299 - 108,659,975 (-)NCBIHuRef
T2T-CHM13v2.09148,479,614 - 148,536,390 (-)NCBIT2T-CHM13v2.0
Ccdc187
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39226,161,659 - 26,184,569 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl226,133,481 - 26,184,569 (-)EnsemblGRCm39 Ensembl
GRCm38226,243,449 - 26,300,204 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl226,243,469 - 26,294,557 (-)EnsemblGRCm38mm10GRCm38
MGSCv37226,127,167 - 26,150,077 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36226,093,656 - 26,116,566 (-)NCBIMGSCv36mm8
Celera225,994,444 - 26,017,147 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map218.54NCBI
Ccdc187
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555134,393,583 - 4,433,285 (+)NCBIChiLan1.0ChiLan1.0
CCDC187
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2113,081,575 - 3,132,538 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan193,083,910 - 3,134,294 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09107,326,280 - 107,377,510 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19136,335,875 - 136,357,822 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9136,307,297 - 136,357,568 (-)Ensemblpanpan1.1panPan2
CCDC187
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1949,165,109 - 49,202,935 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl949,161,034 - 49,202,935 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha948,415,597 - 48,453,413 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0950,041,718 - 50,079,542 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1948,822,167 - 48,859,992 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0949,116,498 - 49,154,318 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0949,164,614 - 49,201,838 (+)NCBIUU_Cfam_GSD_1.0
Ccdc187
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947201,845,740 - 201,910,473 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366691,462,154 - 1,528,114 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC187
(Sus scrofa - pig)		 No map positions available.
CCDC187
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,927,571 - 1,950,730 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660583,263,536 - 3,314,445 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccdc187
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247601,459,803 - 1,499,531 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ccdc187
324 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:74
Count of miRNA genes:67
Interacting mature miRNAs:70
Transcripts:ENSRNOT00000036178
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3653764510778823Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3653764510778823Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
8 3 10 113 53 52 21 22 21 6 123 52 93 39 57 31

Sequence


Ensembl Acc Id: ENSRNOT00000036178   ⟹   ENSRNOP00000032369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl39,070,185 - 9,126,946 (-)Ensembl
Rnor_6.0 Ensembl33,724,656 - 3,747,440 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105690   ⟹   ENSRNOP00000091202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl39,070,192 - 9,126,946 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117358   ⟹   ENSRNOP00000086756
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl39,070,192 - 9,126,946 (-)Ensembl
RefSeq Acc Id: XM_039106121   ⟹   XP_038962049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,468,292 - 29,519,103 (-)NCBI
mRatBN7.239,070,192 - 9,121,027 (-)NCBI
RefSeq Acc Id: XM_039106122   ⟹   XP_038962050
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,468,292 - 29,522,980 (-)NCBI
mRatBN7.239,070,192 - 9,126,366 (-)NCBI
RefSeq Acc Id: XM_039106125   ⟹   XP_038962053
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,468,292 - 29,524,969 (-)NCBI
mRatBN7.239,070,192 - 9,127,001 (-)NCBI
RefSeq Acc Id: XM_039106126   ⟹   XP_038962054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,468,292 - 29,524,957 (-)NCBI
mRatBN7.239,070,192 - 9,127,001 (-)NCBI
RefSeq Acc Id: XM_039106127   ⟹   XP_038962055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,468,292 - 29,525,002 (-)NCBI
mRatBN7.239,070,192 - 9,127,001 (-)NCBI
RefSeq Acc Id: XM_063285235   ⟹   XP_063141305
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,468,292 - 29,524,925 (-)NCBI
RefSeq Acc Id: XM_063285236   ⟹   XP_063141306
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,468,292 - 29,496,286 (-)NCBI
RefSeq Acc Id: XM_063285237   ⟹   XP_063141307
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,468,292 - 29,482,545 (-)NCBI
Ensembl Acc Id: ENSRNOP00000032369   ⟸   ENSRNOT00000036178
RefSeq Acc Id: XP_038962055   ⟸   XM_039106127
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GIU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962053   ⟸   XM_039106125
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GIU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962054   ⟸   XM_039106126
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GIU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962050   ⟸   XM_039106122
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GIU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962049   ⟸   XM_039106121
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GIU0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000091202   ⟸   ENSRNOT00000105690
Ensembl Acc Id: ENSRNOP00000086756   ⟸   ENSRNOT00000117358
RefSeq Acc Id: XP_063141305   ⟸   XM_063285235
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063141306   ⟸   XM_063285236
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063141307   ⟸   XM_063285237
- Peptide Label: isoform X5

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZUA4-F1-model_v2 AlphaFold D3ZUA4 1-961 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691899
Promoter ID:EPDNEW_R2424
Type:single initiation site
Name:Ccdc187_1
Description:coiled-coil domain containing 187
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.033,747,415 - 3,747,475EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565512 AgrOrtholog
BioCyc Gene G2FUF-50389 BioCyc
Ensembl Genes ENSRNOG00000027392 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036178.3 UniProtKB/TrEMBL
  ENSRNOT00000105690.1 UniProtKB/TrEMBL
  ENSRNOT00000117358.1 UniProtKB/TrEMBL
InterPro CEP350 UniProtKB/TrEMBL
NCBI Gene 499759 ENTREZGENE
PANTHER COILED-COIL DOMAIN-CONTAINING PROTEIN 187 UniProtKB/TrEMBL
  PTHR13958 UniProtKB/TrEMBL
PhenoGen Ccdc187 PhenoGen
RatGTEx ENSRNOG00000027392 RatGTEx
UniProt A0A8I6A4B3_RAT UniProtKB/TrEMBL
  A0A8I6GIU0 ENTREZGENE, UniProtKB/TrEMBL
  D3ZUA4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-09-23 Ccdc187  coiled-coil domain containing 187  RGD1565512  similar to hypothetical protein 4932418E24  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1565512  similar to hypothetical protein 4932418E24   RGD1565512_predicted  similar to hypothetical protein 4932418E24 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565512_predicted  similar to hypothetical protein 4932418E24 (predicted)  LOC499759  similar to hypothetical protein 4932418E24  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499759  similar to hypothetical protein 4932418E24      Symbol and Name status set to provisional 70820 PROVISIONAL