MIR486-1 (microRNA mir-486-1) - Rat Genome Database

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Gene: MIR486-1 (microRNA mir-486-1) Sus scrofa
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Symbol: MIR486-1
Name: microRNA mir-486-1
RGD ID: 14128445
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Previously known as: microRNA 486-1; MIR486; ssc-mir-486; ssc-mir-486-1
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11710,758,855 - 10,758,934 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21712,191,266 - 12,191,345 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse:




References
Additional References at PubMed
PMID:16381832   PMID:19917043   PMID:20180025   PMID:21312241   PMID:24499489  


Genomics

Variants

.
Variants in MIR486-1
2 total Variants

Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: NR_035384
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11710,758,855 - 10,758,934 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
miRBase MI0013103 ENTREZGENE
NCBI Gene MIR486-1 ENTREZGENE
RNAcentral URS00004BF1DC RNACentral
  URS000075BA59 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR486-1  microRNA mir-486-1    microRNA 486-1  Symbol and/or name change 5135510 APPROVED