Dmrtc1c1 (DMRT-like family C1c1) - Rat Genome Database

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Gene: Dmrtc1c1 (DMRT-like family C1c1) Rattus norvegicus
Analyze
Symbol: Dmrtc1c1
Name: DMRT-like family C1c1
RGD ID: 1359563
Description: Predicted to be active in nucleus; INTERACTS WITH bisphenol A; copper atom; copper(0).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DMRT-like family C1c; DMRT-like family C1c2; DMRTC1; Dmrtc1c; Dmrtc1c2; LOC363483; similar to RIKEN cDNA 4921520P21
RGD Orthologs
Human
Mouse
Bonobo
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X71,936,907 - 71,944,116 (-)NCBIGRCr8
mRatBN7.2X67,896,973 - 67,904,182 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX67,896,974 - 67,904,182 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX69,366,488 - 69,373,724 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X72,866,724 - 72,873,962 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X70,427,864 - 70,435,102 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X72,684,315 - 72,691,535 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX72,684,329 - 72,691,535 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X73,522,588 - 73,529,808 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X90,790,149 - 90,798,832 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X90,863,582 - 90,872,265 (-)NCBI
CeleraX69,229,382 - 69,243,539 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Comparative Map Data
Dmrtc1c1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X71,936,907 - 71,944,116 (-)NCBIGRCr8
mRatBN7.2X67,896,973 - 67,904,182 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX67,896,974 - 67,904,182 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX69,366,488 - 69,373,724 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X72,866,724 - 72,873,962 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X70,427,864 - 70,435,102 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X72,684,315 - 72,691,535 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX72,684,329 - 72,691,535 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X73,522,588 - 73,529,808 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X90,790,149 - 90,798,832 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X90,863,582 - 90,872,265 (-)NCBI
CeleraX69,229,382 - 69,243,539 (+)NCBICelera
Cytogenetic MapXq22NCBI
DMRTC1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X72,776,890 - 72,848,803 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX72,776,890 - 72,848,803 (+)EnsemblGRCh38hg38GRCh38
GRCh37X71,996,714 - 72,068,637 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X71,913,703 - 71,985,361 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX72,408,584 - 72,412,347 (+)NCBICelera
Cytogenetic MapXq13.1NCBI
HuRefX65,819,845 - 65,823,542 (+)NCBIHuRef
CHM1_1X71,957,325 - 71,961,055 (+)NCBICHM1_1
T2T-CHM13v2.0X71,210,370 - 71,282,297 (+)NCBIT2T-CHM13v2.0
Dmrtc1c1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X101,841,486 - 101,853,556 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX101,846,569 - 101,853,548 (+)EnsemblGRCm39 Ensembl
GRCm38X102,797,880 - 102,809,950 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX102,802,963 - 102,809,942 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 EnsemblX102,847,639 - 102,854,616 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X99,998,302 - 100,005,281 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X99,050,358 - 99,057,335 (-)NCBIMGSCv36mm8
Cytogenetic MapXDNCBI
cM MapX45.73NCBI
LOC117977537
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X72,448,781 - 72,519,996 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X72,452,387 - 72,523,602 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X62,011,910 - 62,083,113 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LOC491957
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X56,769,134 - 56,775,861 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX47,596,149 - 47,602,877 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X58,027,845 - 58,034,402 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X55,742,875 - 55,749,602 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X57,136,778 - 57,142,671 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X56,985,799 - 56,992,506 (+)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in Dmrtc1c1
1 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:108
Count of miRNA genes:93
Interacting mature miRNAs:101
Transcripts:ENSRNOT00000057644
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 1 10 84 31 30 15 12 15 6 100 33 72 45 55 15

Sequence


Ensembl Acc Id: ENSRNOT00000057644   ⟹   ENSRNOP00000054451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX72,684,329 - 72,691,535 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076215   ⟹   ENSRNOP00000068042
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX72,685,300 - 72,686,609 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105775   ⟹   ENSRNOP00000096632
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX67,896,974 - 67,904,182 (-)Ensembl
RefSeq Acc Id: NM_001014222   ⟹   NP_001014244
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X71,936,907 - 71,944,116 (-)NCBI
mRatBN7.2X67,896,973 - 67,904,182 (-)NCBI
Rnor_6.0X72,684,315 - 72,691,535 (+)NCBI
Rnor_5.0X73,522,588 - 73,529,808 (+)NCBI
RGSC_v3.4X90,790,149 - 90,798,832 (-)RGD
CeleraX69,229,382 - 69,243,539 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001014244 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79417 (Get FASTA)   NCBI Sequence Viewer  
  EDM07199 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000093381.1
  ENSRNOP00000096632.1
RefSeq Acc Id: NP_001014244   ⟸   NM_001014222
- UniProtKB: Q6AXP8 (UniProtKB/TrEMBL),   A0A8I6GKM7 (UniProtKB/TrEMBL),   F7FIR9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000054451   ⟸   ENSRNOT00000057644
Ensembl Acc Id: ENSRNOP00000068042   ⟸   ENSRNOT00000076215
Ensembl Acc Id: ENSRNOP00000096632   ⟸   ENSRNOT00000105775
Protein Domains
Doublesex- and mab-3-related transcription factor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AXP8-F1-model_v2 AlphaFold Q6AXP8 1-224 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359563 AgrOrtholog
BioCyc Gene G2FUF-2051 BioCyc
Ensembl Genes ENSRNOG00000037923 Ensembl
  ENSRNOG00000068646 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000069736 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000098333.1 UniProtKB/TrEMBL
  ENSRNOT00000105775.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7113562 IMAGE-MGC_LOAD
InterPro DMRT-C1/C2_C UniProtKB/TrEMBL
KEGG Report rno:363483 UniProtKB/TrEMBL
MGC_CLONE MGC:94958 IMAGE-MGC_LOAD
NCBI Gene 363483 ENTREZGENE
Pfam DMRT-like UniProtKB/TrEMBL
PhenoGen Dmrtc1c1 PhenoGen
RatGTEx ENSRNOG00000037923 RatGTEx
  ENSRNOG00000068646 RatGTEx
  ENSRNOG00000069736 RatGTEx
UniProt A0A8I6GKM7 ENTREZGENE, UniProtKB/TrEMBL
  F7FIR9 ENTREZGENE
  Q6AXP8 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F7FIR9 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-15 Dmrtc1c1  DMRT-like family C1c1  Dmrtc1c2  DMRT-like family C1c2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-09 Dmrtc1c2  DMRT-like family C1c2  Dmrtc1c  DMRT-like family C1c  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Dmrtc1c  DMRT-like family C1c  LOC363483  similar to RIKEN cDNA 4921520P21; DMRTC1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 LOC363483  similar to RIKEN cDNA 4921520P21; DMRTC1      Symbol and Name status set to provisional 70820 PROVISIONAL