Or7g89 (olfactory receptor family 7 subfamily G member 89) - Rat Genome Database

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Gene: Or7g89 (olfactory receptor family 7 subfamily G member 89) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or7g89
Name: olfactory receptor family 7 subfamily G member 89
RGD ID: 1333659
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be active in plasma membrane; INTERACTS WITH acrylamide; bisphenol A; vinclozolin.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: LOC100911893; olfactory receptor 1137; olfactory receptor 7G1-like; olfactory receptor 7G2-like; olfactory receptor gene Olr1137; olfactory receptor Olr1137; Olr1137
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8825,157,056 - 25,157,985 (-)NCBIGRCr8
mRatBN7.2816,880,776 - 16,881,705 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl816,880,776 - 16,881,705 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx820,879,700 - 20,880,629 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0819,177,536 - 19,178,465 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0817,183,732 - 17,184,661 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0819,153,903 - 19,154,832 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl819,153,903 - 19,154,832 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl818,036,845 - 18,037,774 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0819,222,179 - 19,223,108 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4817,279,596 - 17,280,525 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1817,279,595 - 17,280,525 (-)NCBI
Celera818,297,217 - 18,298,146 (-)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or7g89
7 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:77
Count of miRNA genes:57
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000072311, ENSRNOT00000074948
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8124597739Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
2317882Alcrsp24Alcohol response QTL 243.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)8125902202Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001001079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000072311   ⟹   ENSRNOP00000064808
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl819,153,903 - 19,154,832 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000074948   ⟹   ENSRNOP00000064564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl818,036,845 - 18,037,774 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099723   ⟹   ENSRNOP00000092644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl816,880,776 - 16,881,705 (-)Ensembl
RefSeq Acc Id: NM_001001079   ⟹   NP_001001079
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8825,157,056 - 25,157,985 (-)NCBI
mRatBN7.2816,880,776 - 16,881,705 (-)NCBI
Rnor_6.0819,153,903 - 19,154,832 (-)NCBI
Rnor_5.0819,222,179 - 19,223,108 (-)NCBI
RGSC_v3.4817,279,596 - 17,280,525 (-)RGD
Celera818,297,217 - 18,298,146 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001001079 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000092644.1
RefSeq Acc Id: NP_001001079   ⟸   NM_001001079
- UniProtKB: M0R5A1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064808   ⟸   ENSRNOT00000072311
Ensembl Acc Id: ENSRNOP00000064564   ⟸   ENSRNOT00000074948
Ensembl Acc Id: ENSRNOP00000092644   ⟸   ENSRNOT00000099723
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R5A1-F1-model_v2 AlphaFold M0R5A1 1-309 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333659 AgrOrtholog
BioCyc Gene G2FUF-31555 BioCyc
Ensembl Genes ENSRNOG00000047576 Ensembl
  ENSRNOG00000048946 Ensembl
  ENSRNOG00000070961 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000099723.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:405969 UniProtKB/TrEMBL
NCBI Gene 405969 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or7g89 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047576 RatGTEx
  ENSRNOG00000048946 RatGTEx
  ENSRNOG00000070961 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt M0R5A1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or7g89  olfactory receptor family 7 subfamily G member 89  Olr1137  olfactory receptor 1137  Symbol and Name Changed 1299863 APPROVED
2021-03-09 Olr1137  olfactory receptor 1137  LOC100911893  olfactory receptor 7G1-like  Data merged from RGD:6490234 737654 PROVISIONAL
2012-07-05 LOC100911893  olfactory receptor 7G1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Olr1137  olfactory receptor 1137   Olr1137_predicted  olfactory receptor 1137 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1137_predicted  olfactory receptor 1137 (predicted)      Symbol and Name status set to approved 70820 APPROVED