Sel1l2 (SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase) - Rat Genome Database

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Gene: Sel1l2 (SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase) Rattus norvegicus
Analyze
Symbol: Sel1l2
Name: SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase (Ensembl:SEL1L2 adaptor subunit of ERAD E3 ligase)
RGD ID: 1311278
Description: Predicted to be involved in ERAD pathway. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human SEL1L2 (SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase); INTERACTS WITH acrylamide; bisphenol A; trichloroethene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC311470; protein sel-1 homolog 2; RGD1311278; sel-1 suppressor of lin-12-like 2; sel-1 suppressor of lin-12-like 2 (C. elegans); sel-1L2; SEL1L2 adaptor subunit of ERAD E3 ligase; SEL1L2 adaptor subunit of ERAD E3 ubiquitin ligase; SEL1L2 ERAD E3 ligase adaptor subunit; similar to dJ842G6.2 (novel protein imilar to SEL1L (sel-1 (suppressor of lin-12, C.elegans)-like)); suppressor of lin-12-like protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83148,040,624 - 148,167,490 (-)NCBIGRCr8
mRatBN7.23127,586,031 - 127,713,857 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3127,586,976 - 127,713,817 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3131,439,091 - 131,575,563 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03140,023,193 - 140,159,656 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03137,726,333 - 137,862,787 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03134,281,809 - 134,406,560 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3134,281,807 - 134,462,653 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03140,728,731 - 140,854,792 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43128,433,506 - 128,563,511 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13128,339,081 - 128,469,084 (-)NCBI
Celera3126,222,423 - 126,348,674 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
ERAD pathway  (IBA)

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:25002582  


Genomics

Comparative Map Data
Sel1l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83148,040,624 - 148,167,490 (-)NCBIGRCr8
mRatBN7.23127,586,031 - 127,713,857 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3127,586,976 - 127,713,817 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3131,439,091 - 131,575,563 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03140,023,193 - 140,159,656 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03137,726,333 - 137,862,787 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03134,281,809 - 134,406,560 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3134,281,807 - 134,462,653 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03140,728,731 - 140,854,792 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43128,433,506 - 128,563,511 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13128,339,081 - 128,469,084 (-)NCBI
Celera3126,222,423 - 126,348,674 (-)NCBICelera
Cytogenetic Map3q41NCBI
SEL1L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382013,849,247 - 13,995,333 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2013,849,247 - 13,996,443 (-)EnsemblGRCh38hg38GRCh38
GRCh372013,829,893 - 13,975,979 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362013,778,049 - 13,919,262 (-)NCBINCBI36Build 36hg18NCBI36
Build 342013,778,051 - 13,923,863NCBI
Celera2013,900,109 - 14,046,640 (-)NCBICelera
Cytogenetic Map20p12.1NCBI
HuRef2013,784,724 - 13,936,185 (-)NCBIHuRef
CHM1_12013,830,052 - 13,975,987 (-)NCBICHM1_1
T2T-CHM13v2.02013,893,057 - 14,044,585 (-)NCBIT2T-CHM13v2.0
Sel1l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392140,071,519 - 140,231,644 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2140,071,775 - 140,231,626 (-)EnsemblGRCm39 Ensembl
GRCm382140,229,599 - 140,389,710 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2140,229,855 - 140,389,706 (-)EnsemblGRCm38mm10GRCm38
MGSCv372140,055,594 - 140,215,446 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362139,921,299 - 140,081,151 (-)NCBIMGSCv36mm8
Celera2141,415,618 - 141,579,752 (-)NCBICelera
Cytogenetic Map2F3NCBI
cM Map269.2NCBI
Sel1l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541523,290,343 - 23,392,429 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541523,290,343 - 23,392,613 (-)NCBIChiLan1.0ChiLan1.0
SEL1L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22114,740,819 - 14,889,937 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12014,737,650 - 14,886,769 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02013,815,019 - 13,966,202 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12013,800,211 - 13,870,470 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2013,800,212 - 13,945,070 (-)Ensemblpanpan1.1panPan2
SEL1L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1248,678,528 - 8,812,373 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl248,678,959 - 8,812,370 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha248,490,252 - 8,623,564 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0249,088,187 - 9,224,513 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1248,690,542 - 8,824,158 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0248,780,722 - 8,920,621 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0249,135,157 - 9,269,111 (+)NCBIUU_Cfam_GSD_1.0
Sel1l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640157,435,873 - 157,542,369 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364855,867,263 - 5,973,485 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364855,916,463 - 5,975,844 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEL1L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1722,516,558 - 22,627,626 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11722,515,436 - 22,615,444 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21725,197,502 - 25,307,582 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SEL1L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1242,731,035 - 42,887,581 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl242,738,577 - 42,825,557 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660543,014,979 - 3,162,824 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sel1l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474114,859,905 - 14,986,152 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474114,858,962 - 14,986,830 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sel1l2
979 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:52
Count of miRNA genes:49
Interacting mature miRNAs:49
Transcripts:ENSRNOT00000033562
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)384091273129091273Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat

Markers in Region
04.MMHAP52FLB1.seq  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23127,690,737 - 127,690,915 (+)MAPPERmRatBN7.2
Rnor_6.03134,383,504 - 134,383,681NCBIRnor6.0
Rnor_5.03140,831,480 - 140,831,657UniSTSRnor5.0
Celera3126,325,436 - 126,325,613UniSTS
Cytogenetic Map3q41UniSTS


Expression

RNA-SEQ Expression

appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
2 6 11 7 6 2 1 2 14 9 11 1 35 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001014049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC083893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000033562   ⟹   ENSRNOP00000036379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3127,586,976 - 127,681,758 (-)Ensembl
Rnor_6.0 Ensembl3134,281,812 - 134,462,653 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081589   ⟹   ENSRNOP00000072949
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3127,586,976 - 127,713,817 (-)Ensembl
Rnor_6.0 Ensembl3134,281,807 - 134,406,576 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085149   ⟹   ENSRNOP00000073027
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3134,281,885 - 134,340,801 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101153   ⟹   ENSRNOP00000081705
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3127,652,300 - 127,713,817 (-)Ensembl
RefSeq Acc Id: NM_001014049   ⟹   NP_001014071
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,040,624 - 148,167,462 (-)NCBI
mRatBN7.23127,586,973 - 127,713,817 (-)NCBI
Rnor_6.03134,281,809 - 134,406,560 (-)NCBI
Rnor_5.03140,728,731 - 140,854,792 (-)NCBI
RGSC_v3.43128,433,506 - 128,563,511 (-)RGD
Celera3126,222,423 - 126,348,674 (-)RGD
Sequence:
RefSeq Acc Id: XM_039105029   ⟹   XP_038960957
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,040,624 - 148,167,490 (-)NCBI
mRatBN7.23127,586,031 - 127,713,856 (-)NCBI
RefSeq Acc Id: XM_039105030   ⟹   XP_038960958
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,040,624 - 148,167,490 (-)NCBI
mRatBN7.23127,586,031 - 127,713,857 (-)NCBI
RefSeq Acc Id: XM_039105031   ⟹   XP_038960959
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,040,624 - 148,167,490 (-)NCBI
mRatBN7.23127,586,031 - 127,713,857 (-)NCBI
RefSeq Acc Id: XM_039105033   ⟹   XP_038960961
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,040,624 - 148,167,490 (-)NCBI
mRatBN7.23127,586,031 - 127,713,856 (-)NCBI
RefSeq Acc Id: XM_039105034   ⟹   XP_038960962
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,040,624 - 148,167,490 (-)NCBI
mRatBN7.23127,586,031 - 127,713,857 (-)NCBI
RefSeq Acc Id: XM_039105035   ⟹   XP_038960963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,040,624 - 148,167,486 (-)NCBI
mRatBN7.23127,586,031 - 127,713,837 (-)NCBI
RefSeq Acc Id: XM_039105036   ⟹   XP_038960964
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,040,624 - 148,117,166 (-)NCBI
mRatBN7.23127,586,031 - 127,663,516 (-)NCBI
RefSeq Acc Id: XM_039105038   ⟹   XP_038960966
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,040,624 - 148,072,396 (-)NCBI
mRatBN7.23127,586,031 - 127,618,744 (-)NCBI
RefSeq Acc Id: XM_063283794   ⟹   XP_063139864
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,040,624 - 148,167,490 (-)NCBI
RefSeq Acc Id: XM_063283795   ⟹   XP_063139865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,040,624 - 148,167,489 (-)NCBI
RefSeq Acc Id: XM_063283796   ⟹   XP_063139866
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,040,624 - 148,135,165 (-)NCBI
RefSeq Acc Id: XM_063283797   ⟹   XP_063139867
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83148,040,624 - 148,167,490 (-)NCBI
RefSeq Acc Id: NP_001014071   ⟸   NM_001014049
- Peptide Label: precursor
- UniProtKB: Q5XI05 (UniProtKB/Swiss-Prot),   A0A0G2K489 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000036379   ⟸   ENSRNOT00000033562
Ensembl Acc Id: ENSRNOP00000073027   ⟸   ENSRNOT00000085149
Ensembl Acc Id: ENSRNOP00000072949   ⟸   ENSRNOT00000081589
RefSeq Acc Id: XP_038960962   ⟸   XM_039105034
- Peptide Label: isoform X6
- UniProtKB: A6HQM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960959   ⟸   XM_039105031
- Peptide Label: isoform X3
- UniProtKB: A0A0G2K489 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960958   ⟸   XM_039105030
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K489 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960961   ⟸   XM_039105033
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K489 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960957   ⟸   XM_039105029
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K489 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960963   ⟸   XM_039105035
- Peptide Label: isoform X8
- UniProtKB: A6HQM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960964   ⟸   XM_039105036
- Peptide Label: isoform X8
- UniProtKB: A6HQM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960966   ⟸   XM_039105038
- Peptide Label: isoform X10
Ensembl Acc Id: ENSRNOP00000081705   ⟸   ENSRNOT00000101153
RefSeq Acc Id: XP_063139867   ⟸   XM_063283797
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063139864   ⟸   XM_063283794
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063139865   ⟸   XM_063283795
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063139866   ⟸   XM_063283796
- Peptide Label: isoform X8

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XI05-F1-model_v2 AlphaFold Q5XI05 1-688 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692474
Promoter ID:EPDNEW_R2997
Type:initiation region
Name:Sel1l2_1
Description:SEL1L2 ERAD E3 ligase adaptor subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03134,406,564 - 134,406,624EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311278 AgrOrtholog
BioCyc Gene G2FUF-47661 BioCyc
Ensembl Genes ENSRNOG00000004852 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000033562.7 UniProtKB/TrEMBL
  ENSRNOT00000081589.2 UniProtKB/TrEMBL
  ENSRNOT00000101153.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7132857 IMAGE-MGC_LOAD
InterPro Sel1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sel1_AlgK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:311470 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95231 IMAGE-MGC_LOAD
NCBI Gene 311470 ENTREZGENE
PANTHER PROTEIN SEL-1 HOMOLOG 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEL-1-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sel1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sel1l2 PhenoGen
RatGTEx ENSRNOG00000004852 RatGTEx
SMART SEL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP HCP-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K489 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G8B4_RAT UniProtKB/TrEMBL
  A6HQM2 ENTREZGENE, UniProtKB/TrEMBL
  F1LPE2_RAT UniProtKB/TrEMBL
  Q5XI05 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-25 Sel1l2  SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase  Sel1l2  SEL1L2 adaptor subunit of ERAD E3 ubiquitin ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-04-17 Sel1l2  SEL1L2 adaptor subunit of ERAD E3 ubiquitin ligase  Sel1l2  SEL1L2 adaptor subunit of ERAD E3 ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2019-08-09 Sel1l2  SEL1L2 adaptor subunit of ERAD E3 ligase  Sel1l2  SEL1L2 ERAD E3 ligase adaptor subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-27 Sel1l2  SEL1L2 ERAD E3 ligase adaptor subunit  Sel1l2  sel-1 suppressor of lin-12-like 2 (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-27 Sel1l2  sel-1 suppressor of lin-12-like 2 (C. elegans)  RGD1311278  similar to dJ842G6.2 (novel protein imilar to SEL1L (sel-1 (suppressor of lin-12, C.elegans)-like))  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1311278  similar to dJ842G6.2 (novel protein imilar to SEL1L (sel-1 (suppressor of lin-12, C.elegans)-like))  RGD1311278_predicted  similar to dJ842G6.2 (novel protein imilar to SEL1L (sel-1 (suppressor of lin-12, C.elegans)-like)) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1311278_predicted  similar to dJ842G6.2 (novel protein imilar to SEL1L (sel-1 (suppressor of lin-12, C.elegans)-like)) (predicted)  LOC311470_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC311470_predicted  similar to dJ842G6.2 (novel protein imilar to SEL1L (sel-1 (suppressor of lin-12, C.elegans)-like)) (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL