Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ralgdsl3 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Rgl3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of RGL3 mRNA | CTD | PMID:22206623 | Ralgdsl3 | Rat | 17beta-estradiol | multiple interactions | ISO | RGL3 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of RGL3 mRNA | CTD | PMID:30165855 | Ralgdsl3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Rgl3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RGL3 mRNA | CTD | PMID:19770486 | Ralgdsl3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RGL3 mRNA | CTD | PMID:33387578 | Ralgdsl3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Rgl3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to RGL3 promoter] | CTD | PMID:19654925 | Ralgdsl3 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of RGL3 mRNA | CTD | PMID:30071829 | Ralgdsl3 | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of RGL3 protein | CTD | PMID:34915118 | Ralgdsl3 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Rgl3 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of RGL3 exon | CTD | PMID:33297965 | Ralgdsl3 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Rgl3 (Mus musculus) | 6480464 | bisphenol S affects the methylation of RGL3 gene | CTD | PMID:31683443 | Ralgdsl3 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of RGL3 mRNA | CTD | PMID:36041667 | Ralgdsl3 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Rgl3 (Mus musculus) | 6480464 | Fenretinide results in increased expression of RGL3 mRNA | CTD | PMID:28973697 | Ralgdsl3 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of RGL3 mRNA | CTD | PMID:24780913 | Ralgdsl3 | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | RGL3 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of RGL3 polyA tail | CTD | PMID:30157460 | Ralgdsl3 | Rat | all-trans-retinoic acid | increases expression | ISO | RGL3 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of RGL3 mRNA | CTD | PMID:21934132 | Ralgdsl3 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of RGL3 mRNA | CTD | PMID:35163327 | Ralgdsl3 | Rat | arsane | increases methylation | ISO | RGL3 (Homo sapiens) | 6480464 | Arsenic results in increased methylation of RGL3 gene | CTD | PMID:24525453 | Ralgdsl3 | Rat | arsenic atom | increases methylation | ISO | RGL3 (Homo sapiens) | 6480464 | Arsenic results in increased methylation of RGL3 gene | CTD | PMID:24525453 | Ralgdsl3 | Rat | benzo[a]pyrene | decreases expression | ISO | RGL3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of RGL3 mRNA | CTD | PMID:20106945 | Ralgdsl3 | Rat | benzo[a]pyrene | affects methylation | ISO | RGL3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of RGL3 polyA tail | CTD | PMID:30157460 | Ralgdsl3 | Rat | benzo[a]pyrene | decreases methylation | ISO | Rgl3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of RGL3 promoter | CTD | PMID:27901495 | Ralgdsl3 | Rat | benzo[a]pyrene | increases methylation | ISO | RGL3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of RGL3 exon and Benzo(a)pyrene results in increased methylation of RGL3 promoter | CTD | PMID:27901495 | Ralgdsl3 | Rat | benzo[e]pyrene | decreases methylation | ISO | RGL3 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of RGL3 polyA tail | CTD | PMID:30157460 | Ralgdsl3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RGL3 mRNA | CTD | PMID:25181051 | Ralgdsl3 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of RGL3 mRNA | CTD | PMID:36041667 | Ralgdsl3 | Rat | bisphenol A | decreases methylation | ISO | RGL3 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of RGL3 gene | CTD | PMID:31601247 | Ralgdsl3 | Rat | bisphenol F | decreases expression | ISO | Rgl3 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of RGL3 mRNA | CTD | PMID:38685157 | Ralgdsl3 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of RGL3 mRNA | CTD | PMID:36041667 | Ralgdsl3 | Rat | butanal | decreases expression | ISO | RGL3 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of RGL3 mRNA | CTD | PMID:26079696 | Ralgdsl3 | Rat | caffeine | affects phosphorylation | ISO | RGL3 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of RGL3 protein | CTD | PMID:35688186 | Ralgdsl3 | Rat | CGP 52608 | multiple interactions | ISO | RGL3 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to RGL3 gene] | CTD | PMID:28238834 | Ralgdsl3 | Rat | cisplatin | multiple interactions | ISO | RGL3 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of RGL3 mRNA | CTD | PMID:27392435 | Ralgdsl3 | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of RGL3 mRNA | CTD | PMID:26577399 | Ralgdsl3 | Rat | D-mannitol | increases expression | ISO | Rgl3 (Mus musculus) | 6480464 | Mannitol results in increased expression of RGL3 mRNA | CTD | PMID:25270620 | Ralgdsl3 | Rat | dimethylarsinic acid | multiple interactions | ISO | Rgl3 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of RGL3 mRNA | CTD | PMID:34876320 | Ralgdsl3 | Rat | dorsomorphin | multiple interactions | ISO | RGL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Ralgdsl3 | Rat | entinostat | increases expression | ISO | RGL3 (Homo sapiens) | 6480464 | entinostat results in increased expression of RGL3 mRNA | CTD | PMID:26272509 and PMID:27188386 | Ralgdsl3 | Rat | entinostat | multiple interactions | ISO | RGL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RGL3 mRNA | CTD | PMID:27188386 | Ralgdsl3 | Rat | methapyrilene | decreases methylation | ISO | RGL3 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of RGL3 polyA tail | CTD | PMID:30157460 | Ralgdsl3 | Rat | methylarsonic acid | multiple interactions | ISO | Rgl3 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of RGL3 mRNA | CTD | PMID:34876320 | Ralgdsl3 | Rat | methylmercury chloride | increases expression | ISO | RGL3 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of RGL3 mRNA | CTD | PMID:28001369 | Ralgdsl3 | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | Rgl3 (Mus musculus) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of RGL3 mRNA | CTD | PMID:22776087 | Ralgdsl3 | Rat | ozone | multiple interactions | ISO | RGL3 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of RGL3 mRNA | CTD | PMID:35430440 | Ralgdsl3 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of RGL3 mRNA | CTD | PMID:33387578 | Ralgdsl3 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Rgl3 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of RGL3 mRNA | CTD | PMID:37995155 | Ralgdsl3 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of RGL3 mRNA | CTD | PMID:35163327 | Ralgdsl3 | Rat | phenobarbital | increases expression | ISO | Rgl3 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of RGL3 mRNA | CTD | PMID:19270015 | Ralgdsl3 | Rat | phenobarbital | affects expression | ISO | Rgl3 (Mus musculus) | 6480464 | Phenobarbital affects the expression of RGL3 mRNA | CTD | PMID:23091169 | Ralgdsl3 | Rat | phenylmercury acetate | multiple interactions | ISO | RGL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RGL3 mRNA | CTD | PMID:27188386 | Ralgdsl3 | Rat | pirinixic acid | multiple interactions | ISO | RGL3 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of RGL3 mRNA | CTD | PMID:19710929 | Ralgdsl3 | Rat | SB 431542 | multiple interactions | ISO | RGL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Ralgdsl3 | Rat | sodium arsenate | multiple interactions | ISO | Rgl3 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of RGL3 mRNA | CTD | PMID:34876320 | Ralgdsl3 | Rat | sodium arsenite | multiple interactions | ISO | Rgl3 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of RGL3 mRNA | CTD | PMID:34876320 | Ralgdsl3 | Rat | sunitinib | increases expression | ISO | RGL3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of RGL3 mRNA | CTD | PMID:31533062 | Ralgdsl3 | Rat | testosterone | increases expression | ISO | RGL3 (Homo sapiens) | 6480464 | Testosterone results in increased expression of RGL3 mRNA | CTD | PMID:33359661 | Ralgdsl3 | Rat | tetrachloroethene | decreases expression | ISO | Rgl3 (Mus musculus) | 6480464 | Tetrachloroethylene results in decreased expression of RGL3 mRNA | CTD | PMID:28973375 | Ralgdsl3 | Rat | triclosan | decreases expression | ISO | RGL3 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of RGL3 mRNA | CTD | PMID:30510588 | Ralgdsl3 | Rat | valproic acid | increases expression | ISO | RGL3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of RGL3 mRNA | CTD | PMID:26272509 | Ralgdsl3 | Rat | valproic acid | multiple interactions | ISO | RGL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RGL3 mRNA | CTD | PMID:27188386 | |