Inf2 (inverted formin 2) - Rat Genome Database

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Gene: Inf2 (inverted formin 2) Rattus norvegicus
Analyze
Symbol: Inf2
Name: inverted formin 2
RGD ID: 1308350
Description: Predicted to enable actin binding activity and small GTPase binding activity. Predicted to act upstream of or within several processes, including actin nucleation; regulation of cellular component size; and regulation of mitochondrial fission. Predicted to be located in perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate E and focal segmental glomerulosclerosis 5. Orthologous to human INF2 (inverted formin 2); INTERACTS WITH 1-naphthyl isothiocyanate; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: inverted formin, FH2 and WH2 domain containing; inverted formin-2; LOC362790; RGD1308350; similar to hypothetical protein MGC13251
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86137,470,259 - 137,497,039 (+)NCBIGRCr8
mRatBN7.26131,649,162 - 131,675,944 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6131,649,211 - 131,675,941 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.06137,162,593 - 137,180,198 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6137,164,535 - 137,177,622 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06146,170,182 - 146,187,667 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.16137,437,320 - 137,637,548 (+)NCBI
Celera6129,206,114 - 129,210,267 (+)NCBICelera
Celera6129,210,433 - 129,223,633 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,4,6-tribromophenol  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
clofibrate  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenamidone  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
indometacin  (ISO)
inulin  (ISO)
ivermectin  (ISO)
mercury dibromide  (ISO)
methamphetamine  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nitrofen  (EXP)
orphenadrine  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:20023659   PMID:23349293  


Genomics

Comparative Map Data
Inf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86137,470,259 - 137,497,039 (+)NCBIGRCr8
mRatBN7.26131,649,162 - 131,675,944 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6131,649,211 - 131,675,941 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.06137,162,593 - 137,180,198 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6137,164,535 - 137,177,622 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06146,170,182 - 146,187,667 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.16137,437,320 - 137,637,548 (+)NCBI
Celera6129,206,114 - 129,210,267 (+)NCBICelera
Celera6129,210,433 - 129,223,633 (+)NCBICelera
Cytogenetic Map6q32NCBI
INF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814104,681,133 - 104,722,535 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14104,681,146 - 104,722,535 (+)EnsemblGRCh38hg38GRCh38
GRCh3714105,147,470 - 105,188,872 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614104,226,988 - 104,256,992 (+)NCBINCBI36Build 36hg18NCBI36
Build 3414104,246,059 - 104,256,985NCBI
Celera1485,211,992 - 85,241,995 (+)NCBICelera
Cytogenetic Map14q32.33NCBI
HuRef1485,353,176 - 85,383,080 (+)NCBIHuRef
CHM1_114105,093,644 - 105,123,708 (+)NCBICHM1_1
T2T-CHM13v2.01498,923,981 - 98,965,414 (+)NCBIT2T-CHM13v2.0
Inf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912112,555,121 - 112,581,991 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12112,555,218 - 112,581,991 (+)EnsemblGRCm39 Ensembl
GRCm3812112,588,744 - 112,615,557 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12112,588,784 - 112,615,557 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712113,826,995 - 113,853,768 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612113,052,465 - 113,063,365 (+)NCBIMGSCv36mm8
Celera12113,802,332 - 113,829,237 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1261.2NCBI
Inf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555383,163,940 - 3,178,832 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555383,154,670 - 3,176,510 (+)NCBIChiLan1.0ChiLan1.0
INF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215105,872,663 - 105,902,853 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114105,089,203 - 105,119,355 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01485,339,478 - 85,366,336 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114105,143,791 - 105,163,941 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14105,145,779 - 105,163,154 (+)Ensemblpanpan1.1panPan2
INF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1872,275,209 - 72,284,991 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha871,774,391 - 71,791,628 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0872,543,585 - 72,560,033 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1872,231,643 - 72,242,771 (+)NCBIUMICH_Zoey_3.1
UMICH_Zoey_3.1872,226,504 - 72,231,172 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0872,269,581 - 72,286,805 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0872,659,616 - 72,686,357 (+)NCBIUU_Cfam_GSD_1.0
Inf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086401,848,591 - 1,866,379 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936621682,027 - 693,605 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936621677,548 - 693,609 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INF2
(Sus scrofa - pig)		 No map positions available.
INF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12482,628,339 - 82,658,879 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2482,629,090 - 82,660,118 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605370,049,678 - 70,080,143 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Inf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624734558,043 - 567,837 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624734555,188 - 577,930 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Inf2
97 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:454
Count of miRNA genes:213
Interacting mature miRNAs:255
Transcripts:ENSRNOT00000018225, ENSRNOT00000031962
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6122549046137801795Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
2312560Pur20Proteinuria QTL 202.10.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6125628133137801795Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1300076Glom8Glomerulus QTL 879e-09kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6122549046140286318Rat

Markers in Region
RH127822  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26131,675,710 - 131,675,922 (+)MAPPERmRatBN7.2
Rnor_6.06137,180,260 - 137,180,471NCBIRnor6.0
Rnor_5.06146,187,437 - 146,187,648UniSTSRnor5.0
Celera6129,223,400 - 129,223,611UniSTS
RH 3.4 Map6782.5UniSTS
Cytogenetic Map6q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001427265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC088245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000018225   ⟹   ENSRNOP00000018225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6131,649,211 - 131,675,941 (+)Ensembl
Rnor_6.0 Ensembl6137,164,535 - 137,177,622 (+)Ensembl
RefSeq Acc Id: NM_001427264   ⟹   NP_001414193
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,470,286 - 137,497,039 (+)NCBI
RefSeq Acc Id: NM_001427265   ⟹   NP_001414194
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,470,286 - 137,497,039 (+)NCBI
RefSeq Acc Id: XM_039113400   ⟹   XP_038969328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,479,402 - 137,497,036 (+)NCBI
mRatBN7.26131,658,306 - 131,675,944 (+)NCBI
RefSeq Acc Id: XM_039113401   ⟹   XP_038969329
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,479,402 - 137,497,036 (+)NCBI
mRatBN7.26131,658,306 - 131,675,944 (+)NCBI
RefSeq Acc Id: XM_039113404   ⟹   XP_038969332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,479,396 - 137,497,036 (+)NCBI
mRatBN7.26131,658,306 - 131,675,944 (+)NCBI
RefSeq Acc Id: XM_039113407   ⟹   XP_038969335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,479,386 - 137,488,963 (+)NCBI
mRatBN7.26131,658,289 - 131,667,658 (+)NCBI
RefSeq Acc Id: XM_063262150   ⟹   XP_063118220
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,479,402 - 137,497,036 (+)NCBI
RefSeq Acc Id: XM_063262151   ⟹   XP_063118221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,479,402 - 137,497,036 (+)NCBI
RefSeq Acc Id: XM_063262152   ⟹   XP_063118222
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,479,402 - 137,497,036 (+)NCBI
RefSeq Acc Id: XM_063262153   ⟹   XP_063118223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,479,402 - 137,497,036 (+)NCBI
RefSeq Acc Id: XM_063262154   ⟹   XP_063118224
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,470,259 - 137,497,036 (+)NCBI
RefSeq Acc Id: XR_005506354
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,479,402 - 137,497,036 (+)NCBI
mRatBN7.26131,658,305 - 131,675,944 (+)NCBI
RefSeq Acc Id: XR_005506355
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,479,402 - 137,497,036 (+)NCBI
mRatBN7.26131,658,305 - 131,675,944 (+)NCBI
RefSeq Acc Id: XR_005506356
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,479,402 - 137,497,036 (+)NCBI
mRatBN7.26131,658,305 - 131,675,944 (+)NCBI
RefSeq Acc Id: XR_005506358
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,479,402 - 137,497,036 (+)NCBI
mRatBN7.26131,658,306 - 131,675,944 (+)NCBI
RefSeq Acc Id: XR_005506360
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86137,479,384 - 137,488,483 (+)NCBI
mRatBN7.26131,658,287 - 131,667,392 (+)NCBI
Ensembl Acc Id: ENSRNOP00000018225   ⟸   ENSRNOT00000018225
RefSeq Acc Id: XP_038969335   ⟸   XM_039113407
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038969328   ⟸   XM_039113400
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038969329   ⟸   XM_039113401
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038969332   ⟸   XM_039113404
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063118224   ⟸   XM_063262154
- Peptide Label: isoform X5
- UniProtKB: E9PT22 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414193   ⟸   NM_001427264
- Peptide Label: isoform 1
RefSeq Acc Id: NP_001414194   ⟸   NM_001427265
- Peptide Label: isoform 2
RefSeq Acc Id: XP_063118220   ⟸   XM_063262150
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118221   ⟸   XM_063262151
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063118222   ⟸   XM_063262152
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063118223   ⟸   XM_063262153
- Peptide Label: isoform X3
Protein Domains
FH2   GBD/FH3   WH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PT22-F1-model_v2 AlphaFold E9PT22 1-1246 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308350 AgrOrtholog
BioCyc Gene G2FUF-35786 BioCyc
Ensembl Genes ENSRNOG00000028650 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018225.7 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.2220 UniProtKB/TrEMBL
  1.25.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7368069 IMAGE-MGC_LOAD
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  FH2_Formin UniProtKB/TrEMBL
  FH2_Formin_sf UniProtKB/TrEMBL
  FH3_dom UniProtKB/TrEMBL
  GBD/FH3_dom UniProtKB/TrEMBL
  GTPase-bd UniProtKB/TrEMBL
  Inf2 UniProtKB/TrEMBL
  WH2_dom UniProtKB/TrEMBL
MGC_CLONE MGC:109039 IMAGE-MGC_LOAD
NCBI Gene 362790 ENTREZGENE
PANTHER INVERTED FORMIN-2 UniProtKB/TrEMBL
  PTHR46345 UniProtKB/TrEMBL
Pfam Drf_FH3 UniProtKB/TrEMBL
  Drf_GBD UniProtKB/TrEMBL
  FH2 UniProtKB/TrEMBL
  WH2 UniProtKB/TrEMBL
PhenoGen Inf2 PhenoGen
PRINTS PRICHEXTENSN UniProtKB/TrEMBL
PROSITE FH2 UniProtKB/TrEMBL
  GBD_FH3 UniProtKB/TrEMBL
  WH2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028650 RatGTEx
SMART Drf_FH3 UniProtKB/TrEMBL
  Drf_GBD UniProtKB/TrEMBL
  FH2 UniProtKB/TrEMBL
Superfamily-SCOP Formin homology 2 domain (FH2 domain) UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
UniProt E9PT22 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-13 Inf2  inverted formin 2  Inf2  inverted formin, FH2 and WH2 domain containing  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-11-22 Inf2  inverted formin, FH2 and WH2 domain containing  RGD1308350  similar to hypothetical protein MGC13251  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1308350  similar to hypothetical protein MGC13251  RGD1308350_predicted  similar to hypothetical protein MGC13251 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1308350_predicted  similar to hypothetical protein MGC13251 (predicted)  LOC362790_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362790_predicted  similar to hypothetical protein MGC13251 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL