INF2 (inverted formin 2) - Rat Genome Database

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Gene: INF2 (inverted formin 2) Pan paniscus
Analyze
Symbol: INF2
Name: inverted formin 2
RGD ID: 11717092
Description: ENCODES a protein that exhibits actin binding (inferred); small GTPase binding (inferred); INVOLVED IN actin nucleation (ortholog); gene expression (ortholog); regulation of cellular component size (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease axonal type 2O (ortholog); Charcot-Marie-Tooth disease dominant intermediate E (ortholog); FOUND IN perinuclear region of cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inverted formin, FH2 and WH2 domain containing; inverted formin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215105,872,663 - 105,902,853 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114105,089,203 - 105,119,355 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01485,339,478 - 85,366,336 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114105,143,791 - 105,163,941 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14105,145,779 - 105,163,154 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
INF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215105,872,663 - 105,902,853 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114105,089,203 - 105,119,355 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01485,339,478 - 85,366,336 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114105,143,791 - 105,163,941 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14105,145,779 - 105,163,154 (+)Ensemblpanpan1.1panPan2
INF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814104,689,618 - 104,722,535 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14104,681,146 - 104,722,535 (+)EnsemblGRCh38hg38GRCh38
GRCh3714105,155,955 - 105,188,872 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614104,226,988 - 104,256,992 (+)NCBINCBI36Build 36hg18NCBI36
Build 3414104,246,059 - 104,256,985NCBI
Celera1485,211,992 - 85,241,995 (+)NCBICelera
Cytogenetic Map14q32.33NCBI
HuRef1485,353,176 - 85,383,080 (+)NCBIHuRef
CHM1_114105,093,644 - 105,123,708 (+)NCBICHM1_1
T2T-CHM13v2.01498,932,467 - 98,965,414 (+)NCBIT2T-CHM13v2.0
Inf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912112,555,121 - 112,581,991 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12112,555,218 - 112,581,991 (+)EnsemblGRCm39 Ensembl
GRCm3812112,588,744 - 112,615,557 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12112,588,784 - 112,615,557 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712113,826,995 - 113,853,768 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612113,052,465 - 113,063,365 (+)NCBIMGSCv36mm8
Celera12113,802,332 - 113,829,237 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1261.2NCBI
Inf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86137,470,259 - 137,497,039 (+)NCBIGRCr8
mRatBN7.26131,649,162 - 131,675,944 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6131,649,211 - 131,675,941 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.06137,162,593 - 137,180,198 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6137,164,535 - 137,177,622 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06146,170,182 - 146,187,667 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.16137,437,320 - 137,637,548 (+)NCBI
Celera6129,206,114 - 129,210,267 (+)NCBICelera
Celera6129,210,433 - 129,223,633 (+)NCBICelera
Cytogenetic Map6q32NCBI
Inf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555383,163,940 - 3,178,832 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555383,154,670 - 3,176,510 (+)NCBIChiLan1.0ChiLan1.0
INF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1872,275,209 - 72,284,991 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha871,774,391 - 71,791,628 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0872,543,585 - 72,560,033 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1872,231,643 - 72,242,771 (+)NCBIUMICH_Zoey_3.1
UMICH_Zoey_3.1872,226,504 - 72,231,172 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0872,269,581 - 72,286,805 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0872,659,616 - 72,686,357 (+)NCBIUU_Cfam_GSD_1.0
Inf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086401,848,591 - 1,866,379 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936621682,027 - 693,605 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936621677,548 - 693,609 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INF2
(Sus scrofa - pig)		 No map positions available.
INF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12482,628,339 - 82,658,879 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2482,629,090 - 82,660,118 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605370,049,678 - 70,080,143 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Inf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624734558,043 - 567,837 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624734555,188 - 577,930 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000046880   ⟹   ENSPPAP00000024055
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl14105,145,779 - 105,163,154 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000046889   ⟹   ENSPPAP00000024064
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl14105,145,779 - 105,159,731 (+)Ensembl
RefSeq Acc Id: XM_055098072   ⟹   XP_054954047
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v215105,872,663 - 105,902,182 (+)NCBI
NHGRI_mPanPan114105,089,203 - 105,118,682 (+)NCBI
RefSeq Acc Id: XM_055098073   ⟹   XP_054954048
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v215105,872,663 - 105,902,853 (+)NCBI
NHGRI_mPanPan114105,089,203 - 105,119,355 (+)NCBI
Protein Sequences
Protein RefSeqs XP_054954047 (Get FASTA)   NCBI Sequence Viewer  
  XP_054954048 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024055.1
  ENSPPAP00000024064.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000024064   ⟸   ENSPPAT00000046889
RefSeq Acc Id: ENSPPAP00000024055   ⟸   ENSPPAT00000046880
RefSeq Acc Id: XP_054954048   ⟸   XM_055098073
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B749 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054954047   ⟸   XM_055098072
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BA18 (UniProtKB/TrEMBL)
Protein Domains
FH2   GBD/FH3   WH2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035161 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000046880.1 UniProtKB/TrEMBL
  ENSPPAT00000046889.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.2220 UniProtKB/TrEMBL
  1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  FH2_Formin UniProtKB/TrEMBL
  FH2_Formin_sf UniProtKB/TrEMBL
  FH3_dom UniProtKB/TrEMBL
  GBD/FH3_dom UniProtKB/TrEMBL
  GTPase-bd UniProtKB/TrEMBL
  Inf2 UniProtKB/TrEMBL
  WH2_dom UniProtKB/TrEMBL
NCBI Gene INF2 ENTREZGENE
PANTHER INVERTED FORMIN-2 UniProtKB/TrEMBL
  PTHR46345 UniProtKB/TrEMBL
Pfam Drf_FH3 UniProtKB/TrEMBL
  Drf_GBD UniProtKB/TrEMBL
  FH2 UniProtKB/TrEMBL
  WH2 UniProtKB/TrEMBL
PROSITE FH2 UniProtKB/TrEMBL
  GBD_FH3 UniProtKB/TrEMBL
  WH2 UniProtKB/TrEMBL
SMART Drf_FH3 UniProtKB/TrEMBL
  Drf_GBD UniProtKB/TrEMBL
  FH2 UniProtKB/TrEMBL
Superfamily-SCOP Formin homology 2 domain (FH2 domain) UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
UniProt A0A2R9B749 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BA18 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-01-28 INF2  inverted formin 2  INF2  inverted formin, FH2 and WH2 domain containing  Symbol and/or name change 5135510 APPROVED