SMARCC1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1) - Rat Genome Database

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Pathways
Gene: SMARCC1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1) Canis lupus familiaris
Analyze
Symbol: SMARCC1
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 (Ensembl:SWI/SNF related BAF chromatin remodeling complex subunit C1)
RGD ID: 12323461
Description: ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN animal organ morphogenesis (ortholog); insulin receptor signaling pathway (ortholog); negative regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); PARTICIPATES IN SWI/SNF family mediated chromatin remodeling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Animal Disease Models (ortholog); autism spectrum disorder (ortholog); FOUND IN cytoplasm (inferred); nBAF complex (inferred); npBAF complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SWI/SNF complex subunit SMARCC1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12041,165,593 - 41,337,237 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2041,165,522 - 41,335,917 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2041,082,515 - 41,253,825 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02041,648,770 - 41,820,697 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2041,648,442 - 41,819,332 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12040,890,912 - 41,062,805 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02041,292,573 - 41,463,274 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02041,572,012 - 41,744,003 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nBAF complex  (IBA,IEA)
npBAF complex  (IBA,IEA)
nuclear lumen  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)
SWI/SNF complex  (IBA,IEA)
XY body  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SMARCC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12041,165,593 - 41,337,237 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2041,165,522 - 41,335,917 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2041,082,515 - 41,253,825 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02041,648,770 - 41,820,697 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2041,648,442 - 41,819,332 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12040,890,912 - 41,062,805 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02041,292,573 - 41,463,274 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02041,572,012 - 41,744,003 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
SMARCC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38347,585,269 - 47,781,893 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl347,585,269 - 47,782,106 (-)Ensemblhg38GRCh38
GRCh37347,626,759 - 47,823,383 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36347,602,391 - 47,798,410 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34347,602,390 - 47,798,410NCBI
Celera347,569,167 - 47,765,120 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef347,673,262 - 47,870,748 (-)NCBIHuRef
CHM1_1347,577,371 - 47,773,509 (-)NCBICHM1_1
T2T-CHM13v2.0347,604,348 - 47,801,082 (-)NCBIT2T-CHM13v2.0
Smarcc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399109,961,129 - 110,069,773 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9109,946,776 - 110,069,246 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm389110,132,024 - 110,240,178 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,117,708 - 110,240,178 (+)Ensemblmm10GRCm38
MGSCv379110,034,528 - 110,142,682 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369109,977,231 - 110,084,487 (+)NCBIMGSCv36mm8
Celera9109,860,346 - 109,968,637 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.87NCBI
Smarcc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,986,917 - 119,093,161 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8118,989,516 - 119,093,152 (+)EnsemblGRCr8
mRatBN7.28110,111,097 - 110,214,734 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,111,122 - 110,214,720 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8115,726,774 - 115,826,192 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,925,963 - 114,025,381 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,768,732 - 111,868,168 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd8119,875,146 - 119,979,356 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive8121,980,092 - 122,084,303 (+)NCBILyon_Normotensive
Lyon_Hypertensive8120,469,797 - 120,574,008 (+)NCBILyon_Hypertensive
F344_StmMcwi8111,870,861 - 111,974,355 (+)NCBIF344_StmMcwi
Rnor_6.08118,206,678 - 118,326,264 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8118,206,698 - 118,325,537 (+)Ensemblrn6Rnor6.0
Rnor_5.08117,561,593 - 117,677,011 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48114,484,491 - 114,609,850 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8109,398,958 - 109,497,187 (+)NCBICelera
RGSC_v3.18114,503,969 - 114,628,505 (+)NCBI
Cytogenetic Map8q32NCBI
Smarcc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542024,593,830 - 24,729,108 (+)Ensembl
ChiLan1.0NW_00495542024,594,057 - 24,729,108 (+)NCBIChiLan1.0ChiLan1.0
SMARCC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2247,544,150 - 47,739,357 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1347,548,917 - 47,744,126 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0347,487,948 - 47,683,623 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1348,587,903 - 48,781,325 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl348,590,221 - 48,781,248 (-)EnsemblpanPan2panpan1.1
Smarcc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118201,708,506 - 201,858,219 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365961,255,054 - 1,408,038 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365961,257,723 - 1,407,358 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMARCC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1330,409,983 - 30,576,327 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11330,409,979 - 30,576,270 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SMARCC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1228,987,936 - 9,167,689 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl228,987,012 - 9,134,946 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041157,946,014 - 158,135,854 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smarcc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473073,696,749 - 73,856,082 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473073,696,734 - 73,856,082 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Smarcc1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v18100,732,149 - 100,833,651 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in SMARCC1
1377 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000020868   ⟹   ENSCAFP00000019375
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2041,165,522 - 41,335,917 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000068957   ⟹   ENSCAFP00000048300
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2041,165,522 - 41,335,917 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000077525   ⟹   ENSCAFP00000045781
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2041,165,522 - 41,334,266 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000084634   ⟹   ENSCAFP00000044427
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2041,165,522 - 41,335,917 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000085632   ⟹   ENSCAFP00000055611
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2041,165,522 - 41,335,917 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000089448   ⟹   ENSCAFP00000046036
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2041,165,522 - 41,335,917 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845014880   ⟹   ENSCAFP00845011535
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2041,648,442 - 41,819,332 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845015000   ⟹   ENSCAFP00845011633
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2041,648,442 - 41,817,729 (+)Ensembl
RefSeq Acc Id: XM_038427927   ⟹   XP_038283855
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02041,648,770 - 41,820,697 (+)NCBI
RefSeq Acc Id: XM_038503590   ⟹   XP_038359518
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12040,890,912 - 41,062,805 (+)NCBI
RefSeq Acc Id: XM_038566605   ⟹   XP_038422533
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02041,572,012 - 41,744,003 (+)NCBI
RefSeq Acc Id: XM_038630753   ⟹   XP_038486681
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02041,292,573 - 41,463,274 (+)NCBI
RefSeq Acc Id: XM_533845   ⟹   XP_533845
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12041,165,593 - 41,337,237 (+)NCBI
Dog10K_Boxer_Tasha2041,082,515 - 41,253,825 (+)NCBI
Sequence:
RefSeq Acc Id: XP_533845   ⟸   XM_533845
- UniProtKB: A0A8C0P6B2 (UniProtKB/TrEMBL),   A0A8I3RW34 (UniProtKB/TrEMBL),   A0A8C0PD71 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000048300   ⟸   ENSCAFT00000068957
Ensembl Acc Id: ENSCAFP00000019375   ⟸   ENSCAFT00000020868
Ensembl Acc Id: ENSCAFP00000044427   ⟸   ENSCAFT00000084634
Ensembl Acc Id: ENSCAFP00000045781   ⟸   ENSCAFT00000077525
Ensembl Acc Id: ENSCAFP00000046036   ⟸   ENSCAFT00000089448
Ensembl Acc Id: ENSCAFP00000055611   ⟸   ENSCAFT00000085632
RefSeq Acc Id: XP_038359518   ⟸   XM_038503590
RefSeq Acc Id: XP_038486681   ⟸   XM_038630753
RefSeq Acc Id: XP_038283855   ⟸   XM_038427927
- UniProtKB: A0A8C0P6B2 (UniProtKB/TrEMBL),   A0A8I3RW34 (UniProtKB/TrEMBL),   A0A8C0PD71 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038422533   ⟸   XM_038566605
- UniProtKB: A0A8C0P6B2 (UniProtKB/TrEMBL),   A0A8C0PD71 (UniProtKB/TrEMBL),   A0A8I3RW34 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845011633   ⟸   ENSCAFT00845015000
Ensembl Acc Id: ENSCAFP00845011535   ⟸   ENSCAFT00845014880
Protein Domains
Chromo   Myb-like   SANT   SWIRM

Promoters
RGD ID:13686894
Promoter ID:EPDNEW_C4962
Type:multiple initiation site
Name:SMARCC1_1
Description:SWI/SNF related, matrix associated, actin dependent regulatorof chromatin subfamily c member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12041,165,547 - 41,165,607EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013136 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030023066 UniProtKB/TrEMBL
  ENSCAFG00040024728 UniProtKB/TrEMBL
  ENSCAFG00845008451 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000020868.6 UniProtKB/TrEMBL
  ENSCAFT00000077525.2 UniProtKB/TrEMBL
  ENSCAFT00030042415.1 UniProtKB/TrEMBL
  ENSCAFT00030042569.1 UniProtKB/TrEMBL
  ENSCAFT00030042656.1 UniProtKB/TrEMBL
  ENSCAFT00030042739.1 UniProtKB/TrEMBL
  ENSCAFT00040046075.1 UniProtKB/TrEMBL
  ENSCAFT00040046118.1 UniProtKB/TrEMBL
  ENSCAFT00845014880 ENTREZGENE
  ENSCAFT00845014880.1 UniProtKB/TrEMBL
  ENSCAFT00845015000.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro BRCT_dom_sf UniProtKB/TrEMBL
  Chromo/chromo_shadow_dom UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  MARR_BRCT_CHROMO UniProtKB/TrEMBL
  SANT/Myb UniProtKB/TrEMBL
  SANT_dom UniProtKB/TrEMBL
  SMARCC_C UniProtKB/TrEMBL
  SMARCC_N UniProtKB/TrEMBL
  SWIRM UniProtKB/TrEMBL
  SWIRM-assoc UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene SMARCC1 ENTREZGENE
PANTHER CHONDROITIN SULFATE PROTEOGLYCAN 5 UniProtKB/TrEMBL
  CHONDROITIN SULFATE PROTEOGLYCAN 5 -RELATED UniProtKB/TrEMBL
Pfam Myb_DNA-binding UniProtKB/TrEMBL
  SWIRM UniProtKB/TrEMBL
  SWIRM-assoc_1 UniProtKB/TrEMBL
  SWIRM-assoc_2 UniProtKB/TrEMBL
  SWIRM-assoc_3 UniProtKB/TrEMBL
PROSITE MARR_BRCT_CHROMO UniProtKB/TrEMBL
  MYB_LIKE UniProtKB/TrEMBL
  SANT UniProtKB/TrEMBL
  SWIRM UniProtKB/TrEMBL
SMART CHROMO UniProtKB/TrEMBL
  SANT UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
  SSF52113 UniProtKB/TrEMBL
UniProt A0A8C0P5D0_CANLF UniProtKB/TrEMBL
  A0A8C0P6B2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PD71 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TVA7_CANLF UniProtKB/TrEMBL
  A0A8I3RW34 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RW51_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:46535 ENTREZGENE