KCTD8 (potassium channel tetramerization domain containing 8) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Pathways
Gene: KCTD8 (potassium channel tetramerization domain containing 8) Canis lupus familiaris
Analyze
Symbol: KCTD8
Name: potassium channel tetramerization domain containing 8
RGD ID: 12319079
Description: ENCODES a protein that exhibits G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential (ortholog); INVOLVED IN regulation of G protein-coupled receptor signaling pathway (ortholog); FOUND IN postsynapse (inferred); postsynaptic membrane (inferred); presynaptic active zone membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BTB/POZ domain-containing protein KCTD8; potassium channel tetramerisation domain containing 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11340,774,055 - 40,977,984 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1340,738,332 - 40,977,969 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1340,727,836 - 40,931,734 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01341,388,231 - 41,584,543 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1341,389,137 - 41,584,543 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11341,060,793 - 41,264,666 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01341,111,624 - 41,309,252 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01341,498,704 - 41,702,405 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KCTD8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11340,774,055 - 40,977,984 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1340,738,332 - 40,977,969 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1340,727,836 - 40,931,734 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01341,388,231 - 41,584,543 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1341,389,137 - 41,584,543 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11341,060,793 - 41,264,666 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01341,111,624 - 41,309,252 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01341,498,704 - 41,702,405 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
KCTD8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38444,173,903 - 44,448,809 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl444,173,903 - 44,448,928 (-)Ensemblhg38GRCh38
GRCh37444,175,920 - 44,450,826 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36443,871,030 - 44,145,581 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34444,017,200 - 44,291,752NCBI
Celera444,623,428 - 44,899,318 (-)NCBICelera
Cytogenetic Map4p13NCBI
HuRef443,497,191 - 43,773,162 (-)NCBIHuRef
CHM1_1444,175,030 - 44,449,969 (-)NCBICHM1_1
T2T-CHM13v2.0444,140,713 - 44,416,533 (-)NCBIT2T-CHM13v2.0
Kctd8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39569,266,628 - 69,499,052 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl569,266,628 - 69,499,022 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38569,109,285 - 69,341,709 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl569,109,285 - 69,341,679 (-)Ensemblmm10GRCm38
MGSCv37569,500,524 - 69,732,948 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36569,388,420 - 69,620,844 (-)NCBIMGSCv36mm8
Celera566,398,651 - 66,630,271 (-)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map537.01NCBI
Kctd8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81439,127,210 - 39,372,118 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1439,127,379 - 39,372,078 (+)EnsemblGRCr8
mRatBN7.21438,773,274 - 39,018,182 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1438,773,634 - 39,017,554 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1439,130,366 - 39,371,062 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01440,430,399 - 40,671,095 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01438,911,211 - 39,151,931 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1439,401,042 - 39,641,750 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1439,536,490 - 39,788,544 (+)NCBILyon_Normotensive
Lyon_Hypertensive1439,533,828 - 39,785,891 (+)NCBILyon_Hypertensive
F344_StmMcwi1439,554,682 - 39,806,780 (+)NCBIF344_StmMcwi
Rnor_6.01461,912,193 - 62,158,730 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01462,014,881 - 62,262,242 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41441,322,489 - 41,568,787 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1437,968,777 - 38,212,675 (+)NCBICelera
RGSC_v3.11441,325,208 - 41,570,659 (+)NCBI
Cytogenetic Map14p11NCBI
Kctd8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554433,605,922 - 3,835,852 (+)Ensembl
ChiLan1.0NW_0049554433,605,845 - 3,836,717 (+)NCBIChiLan1.0ChiLan1.0
KCTD8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2344,361,845 - 44,645,637 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1444,548,537 - 44,832,098 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0438,495,174 - 38,778,451 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1444,345,609 - 44,627,333 (-)NCBIPanPan1.1PanPan1.1panPan2
Kctd8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528535,117,451 - 35,356,636 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648210,942,514 - 11,180,486 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648210,941,599 - 11,180,776 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCTD8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl834,746,458 - 35,005,694 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1834,745,209 - 35,005,515 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2836,222,599 - 36,223,960 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCTD8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1275,838,643 - 6,116,080 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604751,984,808 - 52,292,949 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kctd8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476122,524,242 - 22,780,475 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476122,523,933 - 22,781,345 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Kctd8
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11126,170,394 - 26,406,463 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in KCTD8
2299 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000002883   ⟹   ENSCAFP00000002672
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1340,738,332 - 40,977,969 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845027246   ⟹   ENSCAFP00845021436
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1341,389,137 - 41,584,543 (-)Ensembl
RefSeq Acc Id: XM_038493657   ⟹   XP_038349585
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11341,060,793 - 41,264,666 (-)NCBI
RefSeq Acc Id: XM_038555972   ⟹   XP_038411900
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01341,498,704 - 41,702,405 (-)NCBI
RefSeq Acc Id: XM_038619924   ⟹   XP_038475852
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01341,111,624 - 41,309,252 (-)NCBI
RefSeq Acc Id: XM_038685515   ⟹   XP_038541443
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01341,388,231 - 41,584,543 (-)NCBI
RefSeq Acc Id: XM_848248   ⟹   XP_853341
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11340,774,055 - 40,977,984 (-)NCBI
Dog10K_Boxer_Tasha1340,727,836 - 40,931,734 (-)NCBI
Sequence:
RefSeq Acc Id: XP_853341   ⟸   XM_848248
- UniProtKB: A0A8C0N4Y1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000002672   ⟸   ENSCAFT00000002883
RefSeq Acc Id: XP_038349585   ⟸   XM_038493657
RefSeq Acc Id: XP_038475852   ⟸   XM_038619924
RefSeq Acc Id: XP_038541443   ⟸   XM_038685515
- UniProtKB: A0A8I3NKS1 (UniProtKB/TrEMBL),   A0A8C0N4Y1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038411900   ⟸   XM_038555972
- UniProtKB: A0A8C0N4Y1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845021436   ⟸   ENSCAFT00845027246
Protein Domains
BTB

Promoters
RGD ID:13685643
Promoter ID:EPDNEW_C3712
Type:single initiation site
Name:KCTD8_1
Description:potassium channel tetramerization domain containing 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11340,978,022 - 40,978,082EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001828 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030011876 UniProtKB/TrEMBL
  ENSCAFG00845015280 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000002883.5 UniProtKB/TrEMBL
  ENSCAFT00030022002.1 UniProtKB/TrEMBL
  ENSCAFT00845027246 ENTREZGENE
  ENSCAFT00845027246.1 UniProtKB/TrEMBL
Gene3D-CATH Potassium Channel Kv1.1, Chain A UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/TrEMBL
  H1_KCTD8_12_16 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/TrEMBL
NCBI Gene KCTD8 ENTREZGENE
PANTHER BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD8 UniProtKB/TrEMBL
  POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/TrEMBL
  H1_KCTD8_12_16 UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/TrEMBL
UniProt A0A8C0N4Y1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NKS1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0N4Y1_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:42311 ENTREZGENE