Advanced Search (OLGA)

Gene: OR8AP1 (olfactory receptor family 8 subfamily AP member 1) Canis lupus familiaris

Analyze

Symbol:

OR8AP1 (Ensembl: OR8D1)

Name:

olfactory receptor family 8 subfamily AP member 1 (Ensembl:olfactory receptor family 8 subfamily D member 1)

RGD ID:

12123561

Description:

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC100688482; olfactory receptor 8D1; olfactory receptor 8D1-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	10,189,052 - 10,190,599 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	10,189,311 - 10,191,143 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	10,239,631 - 10,240,563 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	10,133,849 - 10,134,775 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	10,133,849 - 10,134,775 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	10,205,537 - 10,206,461 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	10,174,836 - 10,175,768 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	10,214,006 - 10,214,938 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

detection of chemical stimulus involved in sensory perception of smell (IEA)

G protein-coupled receptor signaling pathway (IBA,IEA)

sensory perception of smell (IBA,IEA)

signal transduction (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IEA)

Molecular Function

G protein-coupled receptor activity (IEA)

odorant binding (IBA)

olfactory receptor activity (IBA,IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

OR8AP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	10,189,052 - 10,190,599 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	10,189,311 - 10,191,143 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	10,239,631 - 10,240,563 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	10,133,849 - 10,134,775 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	10,133,849 - 10,134,775 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	10,205,537 - 10,206,461 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	10,174,836 - 10,175,768 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	10,214,006 - 10,214,938 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

OR8D1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	124,302,831 - 124,313,949 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	124,302,831 - 124,315,099 (-)	Ensembl			hg38	GRCh38
GRCh37	11	124,172,727 - 124,183,845 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	123,684,946 - 123,685,872 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	11	123,684,945 - 123,685,872	NCBI
Celera	11	121,339,734 - 121,340,660 (-)	NCBI		Celera
Cytogenetic Map	11	q24.2	NCBI
HuRef	11	120,121,914 - 120,122,840 (-)	NCBI		HuRef
CHM1_1	11	124,065,834 - 124,066,760 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	124,331,496 - 124,342,604 (-)	NCBI		T2T-CHM13v2.0

Or8d1b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	38,886,974 - 38,887,900 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	38,883,609 - 38,891,157 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	38,975,678 - 38,976,604 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	38,972,313 - 38,979,861 (+)	Ensembl			mm10	GRCm38
MGSCv37	9	38,783,263 - 38,784,189 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	38,726,249 - 38,727,175 (+)	NCBI		MGSCv36	mm8
Celera	9	36,212,413 - 36,213,339 (+)	NCBI		Celera
Cytogenetic Map	9	A5.1	NCBI
cM Map	9	20.93	NCBI

Olr1271
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	48,024,543 - 48,029,052 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	48,024,562 - 48,029,042 (+)	Ensembl				GRCr8
mRatBN7.2	8	39,127,409 - 39,131,889 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	39,127,352 - 39,131,900 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	44,610,246 - 44,614,726 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	42,894,297 - 42,898,777 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	40,756,373 - 40,760,853 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	8	48,850,539 - 48,855,019 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	8	51,023,685 - 51,028,165 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	8	49,477,627 - 49,482,107 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	8	40,890,144 - 40,894,624 (+)	NCBI		F344_StmMcwi
Rnor_6.0	8	42,776,302 - 42,780,782 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	42,779,545 - 42,780,474 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	42,764,085 - 42,768,565 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	41,166,050 - 41,170,530 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
RGSC_v3.1	8	41,174,815 - 41,179,296 (+)	NCBI
Cytogenetic Map	8	q22	NCBI

LOC100516819
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	51,282,954 - 51,283,880 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	51,282,954 - 51,283,924 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	56,756,505 - 56,757,475 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Variants

Variants in OR8AP1
33 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	nervous system	reproductive system
4	4	4	5

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_014113249	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038477604	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038535493	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038599716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038664238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000036321 ⟹ ENSCAFP00000038272

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	10,189,311 - 10,191,143 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845020413 ⟹ ENSCAFP00845015997

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	10,133,849 - 10,134,775 (+)	Ensembl

RefSeq Acc Id:

XM_014113249 ⟹ XP_013968724

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	10,189,052 - 10,190,599 (+)	NCBI
Dog10K_Boxer_Tasha	5	10,239,631 - 10,240,563 (+)	NCBI

Sequence:

show sequence

GAATGGAAGGGGGAAACAGGGGAAAATAAACAGTACATACTAATATAAACATAGGAAACAAAGG
AAAACAAAAAGTACATACTAATATAAACACAGGACAGGGTGCTTTAGGGAGACAGGACCAGAGA
TAATGAAAGCTGTGATTCAGTATCTGTTTCTGGACTTTCCTTTTGCAGGTCTGGTTTTGTTTAG
ACAGAGAGTAAAGATCCACTTTAATATACTTCTTCTTTTCCAATTCCACAGAGATCTCTAAAGA
AGAATGGTTGCAGGAAATCATTCTACAGCATCCGAGTTTGTGTTAGTGGGTCTAACACAGCAGC
CAGAGCTCCAGCAGCCTCTCTTCCTCCTGTTCCTGGGAATCTATATCCTGACGGTGGTGGGGAA
CTTGGGCTTGATTCTCCTGATTACCCTGAGCCCTTCCCTTCACACCCCCATGTACTACTTCCTC
AGCAGCTTATCATTCATCGATCTCTGCTATTCCTCTGTCATTACCCCCAAAATGCTGGTGAACT
TCTTAGGGAGGAAAAATATGATCCTTTATTCTGAGTGCATGACACAGCTCTTTTTCTTCGTGGT
CTTTGTAGTGGCTGAGGGTTACCTCCTGACCATGATGGCATACGATCGCTACGTTGCCATCTGT
AGCCCCCTACTTTACAGTGTGGTCATGTCCCCCCGAGTGTGCTCACTGCTGGTGCTGGTTGCCT
TCAGCCTGGGCTTTCTCTCCGCCGTGGCCCATACAAGTGCCATGATGCAACTGTCTTTCTGCAG
ATCCCACATCATCAACCATTACTTCTGTGATGTTCTTCATATGCTCAATCTCTCCTGCTCCGAT
ACACACCTCAATGAGCTTCTGCTTTTTTATCATGCGGGACTTAACNACTTGGTACCACTCTGGG
CAGTCTGCATTTCCTATGCCTTCATCTTCTACAGCATCGTTCGAATCCGATCTTCAGAGGGACG
GTCCAAAGCCTTTGGTACTTGCAGCTCTCATCTCATGGCTGTGGGGATCTTCTTTGGGTCTATC
ACATTCATGTATTTCAAGCCCCCTTCCAGTAATTCCCTGGAACAAGAGAAGGTGTCCTCAGTGT
TCTACACCACAGTGATCCCCATGCTGAACCCTTTAATATACAGTCTGAGAAACAAGGATGTCAA
GAAAGCATTGAGGAAGGTTTTGGTGAAGAAATGAGTCTTGCTTTTGGAGATTTATAGGTGGGAG
AAATTAAGGTTTCAACAAAGTATGTCCTTTTTTGTTCATTTTTCCTTGTTAGCCAGTCATGATA
TGTATACTATCTGGACTTTTAAAATACTTCTCCATCTGTAATTGATTCCATTTTCTCAATGAAA
TGAAAAGGAGTTTGGTAAAGCAAGTTTTAGTGTTCTTATTTTGGGGCAGGAAAACTGAGGTTTA
GACAGTTTTATTTTTTCCTAACTTACTGTGGTAGAAGAGGAATGAGAATTCTTATTTTCTCCAG
TGTTAGTCTTCCCCACCCCCCCCAACATCCTGTGTTTGCTTTATGGAATACCTGCTGTGTAGGT
GGTGCTCAGTTGT

hide sequence

RefSeq Acc Id:

XM_038477604 ⟹ XP_038333532

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	5	10,205,537 - 10,206,461 (+)	NCBI

RefSeq Acc Id:

XM_038535493 ⟹ XP_038391421

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	5	10,214,006 - 10,214,938 (+)	NCBI

RefSeq Acc Id:

XM_038599716 ⟹ XP_038455644

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	5	10,174,836 - 10,175,768 (+)	NCBI

RefSeq Acc Id:

XM_038664238 ⟹ XP_038520166

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	10,133,849 - 10,134,775 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_013968724	(Get FASTA)	NCBI Sequence Viewer
	XP_038333532	(Get FASTA)	NCBI Sequence Viewer
	XP_038391421	(Get FASTA)	NCBI Sequence Viewer
	XP_038455644	(Get FASTA)	NCBI Sequence Viewer
	XP_038520166	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000038272.3
	ENSCAFP00845015997
	ENSCAFP00845015997.1

RefSeq Acc Id:

XP_013968724 ⟸ XM_014113249

- UniProtKB:

A0A8P0NQ04 (UniProtKB/TrEMBL), A0A8C0KAW2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVAGNHSTASEFVLVGLTQQPELQQPLFLLFLGIYILTVVGNLGLILLITLSPSLHTPMYYFLS
SLSFIDLCYSSVITPKMLVNFLGRKNMILYSECMTQLFFFVVFVVAEGYLLTMMAYDRYVAICS
PLLYSVVMSPRVCSLLVLVAFSLGFLSAVAHTSAMMQLSFCRSHIINHYFCDVLHMLNLSCSDT
HLNELLLFYHAGLNXLVPLWAVCISYAFIFYSIVRIRSSEGRSKAFGTCSSHLMAVGIFFGSIT
FMYFKPPSSNSLEQEKVSSVFYTTVIPMLNPLIYSLRNKDVKKALRKVLVKK

hide sequence

Ensembl Acc Id:

ENSCAFP00000038272 ⟸ ENSCAFT00000036321

RefSeq Acc Id:

XP_038333532 ⟸ XM_038477604

RefSeq Acc Id:

XP_038455644 ⟸ XM_038599716

RefSeq Acc Id:	XP_038520166 ⟸ XM_038664238
- UniProtKB:	A0A8I3NIS4 (UniProtKB/TrEMBL), A0A8C0KAW2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038391421 ⟸ XM_038535493
- UniProtKB:	A0A8C0KAW2 (UniProtKB/TrEMBL), A0A8I3NIS4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845015997 ⟸ ENSCAFT00845020413

Protein Domains

G-protein coupled receptors family 1 profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000023573	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00845011517	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000036321.4	UniProtKB/TrEMBL
	ENSCAFT00845020413	ENTREZGENE
	ENSCAFT00845020413.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	Olfact_rcpt	UniProtKB/TrEMBL
NCBI Gene	LOC100688482	ENTREZGENE
PANTHER	OLFACTORY RECEPTOR	UniProtKB/TrEMBL
Pfam	7tm_4	UniProtKB/TrEMBL
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
	OLFACTORYR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
SMART	7TM_GPCR_Srsx	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A8C0KAW2	ENTREZGENE
	A0A8I3NIS4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NQ04	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:98587	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-03-10	OR8AP1	olfactory receptor family 8 subfamily AP member 1	LOC100688482	olfactory receptor 8D1-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message