ABCA3 (ATP binding cassette subfamily A member 3) - Rat Genome Database

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Gene: ABCA3 (ATP binding cassette subfamily A member 3) Pan paniscus
Analyze
Symbol: ABCA3
Name: ATP binding cassette subfamily A member 3
RGD ID: 11762436
Description: ENCODES a protein that exhibits ABC-type transporter activity (inferred); ABC-type xenobiotic transporter activity (inferred); ATP binding (inferred); INVOLVED IN positive regulation of vesicle fusion (ortholog); response to glucocorticoid (ortholog); PARTICIPATES IN altered surfactant homeostasis pathway; surfactant homeostasis pathway; transport pathway; ASSOCIATED WITH carbamoyl phosphate synthetase I deficiency disease (ortholog); chromosome 22q11.2 deletion syndrome, distal (ortholog); Colorectal Neoplasms (ortholog); FOUND IN alveolar lamellar body membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-binding cassette sub-family A member 3; phospholipid-transporting ATPase ABCA3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,777,564 - 2,841,351 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,558,502 - 6,622,328 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,132,435 - 1,196,226 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,376,006 - 2,437,427 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,376,006 - 2,437,427 (-)EnsemblpanPan2panpan1.1
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ABCA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,777,564 - 2,841,351 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,558,502 - 6,622,328 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,132,435 - 1,196,226 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,376,006 - 2,437,427 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,376,006 - 2,437,427 (-)EnsemblpanPan2panpan1.1
ABCA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,275,881 - 2,340,728 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,275,878 - 2,340,749 (-)Ensemblhg38GRCh38
GRCh37162,325,882 - 2,390,729 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,265,880 - 2,330,748 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34162,265,883 - 2,330,595NCBI
Celera162,540,308 - 2,605,176 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,251,902 - 2,305,693 (-)NCBIHuRef
CHM1_1162,325,836 - 2,390,894 (-)NCBICHM1_1
T2T-CHM13v2.0162,298,327 - 2,363,113 (-)NCBIT2T-CHM13v2.0
Abca3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,570,997 - 24,629,178 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,570,924 - 24,629,175 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381724,351,921 - 24,410,204 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,351,950 - 24,410,201 (+)Ensemblmm10GRCm38
MGSCv371724,488,991 - 24,547,146 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361724,079,646 - 24,137,801 (+)NCBIMGSCv36mm8
Celera1724,865,306 - 24,922,824 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.38NCBI
Abca3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,886,948 - 13,944,286 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1013,887,083 - 13,944,285 (+)EnsemblGRCr8
mRatBN7.21013,382,439 - 13,439,748 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,382,540 - 13,439,745 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1018,128,894 - 18,186,191 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,617,736 - 17,675,035 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,116,920 - 13,174,223 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1016,810,482 - 16,867,673 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1017,471,885 - 17,529,187 (+)NCBILyon_Normotensive
Lyon_Hypertensive1019,163,811 - 19,221,004 (+)NCBILyon_Hypertensive
F344_StmMcwi1019,156,822 - 19,214,122 (+)NCBIF344_StmMcwi
Rnor_6.01013,723,365 - 13,780,558 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,723,405 - 13,779,963 (+)Ensemblrn6Rnor6.0
Rnor_5.01013,539,739 - 13,597,488 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41013,619,865 - 13,665,066 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1013,062,889 - 13,120,240 (+)NCBICelera
RGSC_v3.11013,605,987 - 13,664,059 (+)NCBI
Cytogenetic Map10q12NCBI
Abca3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,933,550 - 14,989,492 (+)Ensembl
ChiLan1.0NW_00495544214,933,550 - 14,989,492 (+)NCBIChiLan1.0ChiLan1.0
ABCA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,679,312 - 38,712,868 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,679,324 - 38,712,648 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha639,912,394 - 39,952,493 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0638,981,385 - 39,021,683 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl638,981,033 - 39,021,741 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,666,452 - 38,706,734 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,638,971 - 38,679,063 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,117,459 - 39,157,746 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Abca3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,931,363 - 104,975,718 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,736,207 - 1,778,116 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,735,206 - 1,778,100 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,698,895 - 39,732,978 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1339,689,133 - 39,732,466 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,433,553 - 42,469,125 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ABCA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,171,487 - 2,218,851 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606828,821,142 - 28,886,157 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abca3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462482484,430 - 144,062 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462482485,369 - 144,053 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Abca3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v191,641,001 - 1,698,253 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000036918   ⟹   ENSPPAP00000014238
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl162,376,006 - 2,437,427 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000036943   ⟹   ENSPPAP00000014263
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl162,376,800 - 2,425,346 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000036949   ⟹   ENSPPAP00000014269
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl162,376,800 - 2,425,346 (-)Ensembl
RefSeq Acc Id: XM_034940937   ⟹   XP_034796828
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2182,777,564 - 2,841,351 (-)NCBI
NHGRI_mPanPan1166,558,502 - 6,622,328 (-)NCBI
Mhudiblu_PPA_v0161,132,435 - 1,196,226 (-)NCBI
RefSeq Acc Id: XM_055100640   ⟹   XP_054956615
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2182,777,564 - 2,840,436 (-)NCBI
NHGRI_mPanPan1166,558,502 - 6,621,363 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034796828 (Get FASTA)   NCBI Sequence Viewer  
  XP_054956615 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000014238.1
  ENSPPAP00000014263.1
  ENSPPAP00000014269.1
  ENSPPAP00050050461
RefSeq Acc Id: XP_034796828   ⟸   XM_034940937
- UniProtKB: A0A2R9AFD1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000014238   ⟸   ENSPPAT00000036918
Ensembl Acc Id: ENSPPAP00000014269   ⟸   ENSPPAT00000036949
Ensembl Acc Id: ENSPPAP00000014263   ⟸   ENSPPAT00000036943
RefSeq Acc Id: XP_054956615   ⟸   XM_055100640
- UniProtKB: A0A2R9AFD1 (UniProtKB/TrEMBL)
Protein Domains
ABC transporter


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030120 Ensembl, UniProtKB/TrEMBL
  ENSPPAG00050035905 ENTREZGENE
Ensembl Transcript ENSPPAT00000036918.1 UniProtKB/TrEMBL
  ENSPPAT00000036943.1 UniProtKB/TrEMBL
  ENSPPAT00000036949.1 UniProtKB/TrEMBL
  ENSPPAT00050076761 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ABC2_TM UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/TrEMBL
  ABC_transporter_CS UniProtKB/TrEMBL
  ABCA UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  R2_ABCA1-4-like UniProtKB/TrEMBL
NCBI Gene ABCA3 ENTREZGENE
PANTHER ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED UniProtKB/TrEMBL
  PTHR19229 UniProtKB/TrEMBL
Pfam ABC2_membrane_3 UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
  R1_ABCA1 UniProtKB/TrEMBL
PROSITE ABC_TRANSPORTER_1 UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9AAH7_PANPA UniProtKB/TrEMBL
  A0A2R9AFD1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AFF6_PANPA UniProtKB/TrEMBL