| 12311013 | RRBP1 | ribosome binding protein 1 | INVOLVED IN signal transduction; FOUND IN endoplasmic reticulum membrane | 24 | 5349415 | 5390673 | Dog | 13 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12416215 | ERBB2 | erb-b2 receptor tyrosine kinase 2 | ENCODES a protein that exhibits Hsp90 protein binding (ortholog); protein tyrosine kinase activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN axon regeneration (ortholog); cell surface receptor signaling pathway (ortholog); cellular response to epidermal growth factor sti mulus (ortholog); PARTICIPATES IN altered epidermal growth factor/neuregulin signaling pathway; endometrial cancer pathway; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); amblyopia (ortholog); Animal Disease Models (ortholog); FOUND IN apical plasma membrane (ortholog); basal plasma membrane (ortholog); basolateral plasma membrane (ortholog) | 9 | 22760373 | 22785367 | Dog | 335 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12307590 | APOE | apolipoprotein E | ENCODES a protein that exhibits amyloid-beta binding (ortholog); heparan sulfate proteoglycan binding (ortholog); heparin binding (ortholog); INVOLVED IN AMPA glutamate receptor clustering (ortholog); artery development (ortholog); artery morphogenesis (ortholog); PARTICIPATES IN altered lipoprotein metabolic pathway; lipoprotein metabolic pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); adenocarcinoma (ortholog); age related macular degeneration 1 (ortholog); FOUND IN cell surface (ortholog); chylomicron (ortholog); dendrite (ortholog) | 1 | 110525717 | 110528534 | Dog | 446 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, MODEL [RefSeq] |
| 12222722 | DLA-DRB1 | MHC class II DLA DRB1 beta chain | ENCODES a protein that exhibits CD4 receptor binding (ortholog); polysaccharide binding (ortholog); T cell receptor binding (ortholog); INVOLVED IN antigen processing and presentation of endogenous peptide antigen via MHC class II (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); humoral immune response (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); Actinic Prurigo (ortholog); acute disseminated encephalomyelitis (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); immunological synapse (ortholog) | 12 | 2151409 | 2164564 | Dog | 265 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12313334 | DLA88 | MHC class I DLA-88 | ENCODES a protein that exhibits protein-folding chaperone binding (ortholog); TAP binding (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class Ib (ortholog); protection from natural killer cell mediated cytotoxicity (ortholog); regulation of dendriti c cell differentiation (ortholog); ASSOCIATED WITH Acute Anterior Uveitis (ortholog); acute retinal necrosis syndrome (ortholog); allergic asthma (ortholog); FOUND IN cell surface (ortholog); endoplasmic reticulum (ortholog); Golgi apparatus (ortholog) | 12 | 892442 | 895691 | Dog | 122 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12055194 | FGF1 | fibroblast growth factor 1 | ENCODES a protein that exhibits fibroblast growth factor receptor binding (ortholog); growth factor activity (ortholog); heparin binding (ortholog); INVOLVED IN activation of protein kinase B activity (ortholog); branch elongation involved in ureteric bud branching (ortholog); cellular response to h eat (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); brain ischemia (ortholog); cleft lip (ortholog); FOUND IN cytosol (ortholog); extracellular region (ortholog); extracellular space (ortholog) | 2 | 37467431 | 37554770 | Dog | 122 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, MODEL [RefSeq] |
| 12158748 | IVL | involucrin | INVOLVED IN keratinocyte differentiation (ortholog); peptide cross-linking (ortholog); regulation of antibacterial peptide production (ortholog); ASSOCIATED WITH Skin Neoplasms (ortholog); squamous cell carcinoma (ortholog); FOUND IN cornified envelope (ortholog); cytosol (ortholog) | 17 | 61714470 | 61716961 | Dog | 12 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, MODEL [RefSeq] |
| 12286148 | LHB | luteinizing hormone subunit beta | ENCODES a protein that exhibits hormone activity (inferred); INVOLVED IN luteinizing hormone signaling pathway (ortholog); PARTICIPATES IN luteinizing hormone signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); Bradycardia (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN cy toplasm (ortholog) | 1 | 107382855 | 107384029 | Dog | 31 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 12059322 | RAB5A | RAB5A, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (ortholog); GDP binding (ortholog); GDP-dissociation inhibitor binding (ortholog); INVOLVED IN endocytosis (ortholog); endosomal transport (ortholog); endosome organization (ortholog); PARTICIPATES IN autophagy pathway; insulin responsive facilitati ve sugar transporter mediated glucose transport pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH Myocardial Ischemia (ortholog); FOUND IN exocytic vesicle; lipid droplet; sorting endosome | 23 | 23303650 | 23333571 | Dog | 144 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12154550 | RAB7A | RAB7A, member RAS oncogene family | ENCODES a protein that exhibits GDP binding (ortholog); GTP binding (ortholog); small GTPase binding (ortholog); INVOLVED IN early endosome to late endosome transport; epidermal growth factor catabolic process; bone resorption (ortholog); PARTICIPATES IN autophagy pathway; interleukin-12 signaling p athway; ASSOCIATED WITH Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease type 2 (ortholog); Charcot-Marie-Tooth disease type 2B (ortholog); FOUND IN exocytic vesicle; synaptic vesicle membrane; alveolar lamellar body (ortholog) | 20 | 2704716 | 2776518 | Dog | 102 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |