| 12296991 | SP1 | Sp1 transcription factor | ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); cellular response to insulin stimulus (ortholog); cellu lar response to wortmannin (ortholog); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Carotid Artery Injuries (ortholog); Colorectal Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN protein-DNA complex (ortholog); INTERACTS WITH anthra[1,9-cd]pyrazol-6(2H)-one; bisphenol A; sodium chloride | 27 | 1802587 | 1861187 | Dog | 132 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12275137 | MED23 | mediator complex subunit 23 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN positive regulation of gene expression (ortholog); positive regulation of T cell extravasation (ortholog); protein ubiquitination (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH autosomal recessive intellectual developmental disorder 18 (ortholog); Fraser syndrome 3 (ortholog); genetic disease (ortholog); FOUND IN ubiquitin ligase complex (ortholog) | 12 | 195638 | 240741 | Dog | 26 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12387971 | TLE2 | TLE family member 2, transcriptional corepressor | ENCODES a protein that exhibits transcription corepressor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of canonical Wnt signaling pathway (inferred); negative regulation of DNA-templated transcription (inferred); ASSOCIATED WITH lymphopenia (ortholog); neutropenia (ortholog); FOUND IN nuclear body (inferred); nucleus (inferred) | 20 | 56138654 | 56157625 | Dog | 23 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12333865 | TLE3 | TLE family member 3, transcriptional corepressor | ENCODES a protein that exhibits transcription coactivator activity (inferred); transcription corepressor activity (inferred); INVOLVED IN regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Breast Neoplasms (ortholog); rheumatoid art hritis (ortholog); FOUND IN beta-catenin-TCF complex (inferred); chromatin (inferred); nucleoplasm (inferred) | 30 | 33803719 | 33895204 | Dog | 31 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12410233 | TLE4 | TLE family member 4, transcriptional corepressor | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polyme rase II (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); Experimental Mammary Neoplasms (ortholog); FOUND IN beta-catenin-TCF complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 1 | 79126261 | 79268052 | Dog | 32 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12173689 | TLE6 | TLE family member 6, subcortical maternal complex member | ENCODES a protein that exhibits structural constituent of cytoplasmic lattice (inferred); INVOLVED IN actin filament organization (ortholog); embryonic process involved in female pregnancy (ortholog); endoplasmic reticulum localization (ortholog); ASSOCIATED WITH Oocyte/Zygote/Embryo Maturation Arre st 15 (ortholog); FOUND IN cell cortex (ortholog); cytoplasmic lattice (ortholog); protein-containing complex (ortholog) | 20 | 56159045 | 56169740 | Dog | 41 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12260971 | MED17 | mediator complex subunit 17 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); protein ubiquitination (ortholog); regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcript ion pathway; ASSOCIATED WITH endometriosis (ortholog); genetic disease (ortholog); infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly (ortholog); FOUND IN ubiquitin ligase complex (ortholog) | 21 | 6967304 | 6990542 | Dog | 36 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12097109 | MED26 | mediator complex subunit 26 | ENCODES a protein that exhibits transcription coregulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription pathway; FOUND IN mediator complex (inferred); membrane (inf erred); nucleoplasm (inferred) | 20 | 45923034 | 45977118 | Dog | 26 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12069668 | MED27 | mediator complex subunit 27 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN protein ubiquitination (ortholog); regulation of transcription by RNA polymerase II (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED W ITH genetic disease (ortholog); intellectual disability (ortholog); NEURODEVELOPMENTAL DISORDER WITH SPASTICITY, CATARACTS, AND CEREBELLAR HYPOPLASIA (ortholog); FOUND IN ubiquitin ligase complex (ortholog) | 9 | 52136652 | 52331676 | Dog | 27 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12256784 | MED7 | mediator complex subunit 7 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN protein ubiquitination (ortholog); regulation of transcription by RNA polymerase II (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOUND IN ubi quitin ligase complex (ortholog) | 4 | 52998748 | 53004063 | Dog | 31 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 12389071 | MED14 | mediator complex subunit 14 | ENCODES a protein that exhibits transcription coactivator activity (inferred); transcription coregulator activity (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN cortisol signaling pathway; RNA polymerase II transcription pathway; ASSOCIATED WITH endometriosis (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN mediator complex (inferred); nucleus (inferred) | X | 35125270 | 35191260 | Dog | 28 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12164006 | SP100 | SP100 nuclear antigen | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein homodimerization activity (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcri ption (ortholog); negative regulation of viral transcription (ortholog); response to cytokine (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN nuclear periphery (ortholog) | 25 | 42538428 | 42635825 | Dog | 68 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12174811 | SP110 | SP110 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN positive regulation of apoptotic process (ortholog); response to bacterium (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatic venoocclusive disease with immunod eficiency (ortholog); tuberculosis (ortholog); FOUND IN nuclear lumen (inferred); nucleoplasm (inferred); nucleus (inferred) | 25 | 42418565 | 42459098 | Dog | 19 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12129514 | SP140 | SP140 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN defense response (inferred); ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (inferred); nuclear lumen (inferred); nucleolus (inferred) | 25 | 42459013 | 42527141 | Dog | 16 | symbol , old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12151562 | LOC100686622 | nuclear body protein SP140-like protein | FOUND IN nucleus (inferred) | 25 | 42643992 | 42684365 | Dog | 1 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12232499 | SEC11A | SEC11 homolog A, signal peptidase complex subunit | ENCODES a protein that exhibits serine-type endopeptidase activity (ortholog); INVOLVED IN signal peptide processing (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN signal peptidase complex | 3 | 53940644 | 53980422 | Dog | 26 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12253975 | SPA17 | sperm autoantigenic protein 17 | INVOLVED IN binding of sperm to zona pellucida (inferred); single fertilization (inferred); ASSOCIATED WITH Merkel cell carcinoma (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred); external side of plasma membrane (inferred) | 5 | 9719222 | 9731521 | Dog | 22 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |