| 12157486 | NXT1 | nuclear transport factor 2 like export factor 1 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN mRNA export from nucleus (ortholog); protein export from nucleus (ortholog); RNA export from nucleus (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; FOUND IN cytosol (ortholog); n uclear pore (ortholog); nuclear RNA export factor complex (ortholog) | 24 | 295064 | 299316 | Dog | 28 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 12333962 | ALYREF | Aly/REF export factor | ENCODES a protein that exhibits C5-methylcytidine-containing RNA reader activity (ortholog); molecular adaptor activity (ortholog); RNA folding chaperone (ortholog); INVOLVED IN mRNA metabolic process (ortholog); RNA export from nucleus (ortholog); PARTICIPATES IN NXF1-NXT1 >NXT1 export pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); human immunodeficiency virus infectious disease (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); chromosome, telomeric region (ortholog); cytoplasm (ortholog) | 9 | 398207 | 402787 | Dog | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 12404311 | DDX19B | DEAD-box helicase 19B | ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); PARTICIPATES IN NXF1-NXT1 export pathway; FOUND IN nuclear envelope (ortholog) | 5 | 76314675 | 76336318 | Dog | 26 | description | gene, protein-coding, MODEL [RefSeq] |
| 12113861 | DDX39B | DExD-box helicase 39B | ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN liver development (ortholog); positive regulation of cell growth involved in cardiac muscle cell development (ortholog); positive regulation of DNA biosynthetic process (ortholog); PARTICIPATES IN NXF1-NXT1 tyle='font-weight:700;'>NXT1 export pathway; spliceosome pathway; ASSOCIATED WITH type 1 diabetes mellitus (ortholog); FOUND IN nuclear matrix (ortholog); protein-containing complex (ortholog) | 12 | 1032377 | 1044465 | Dog | 62 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12096279 | GLE1 | GLE1 RNA export mediator | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN mRNA export from nucleus (inferred); mRNA transport (inferred); poly(A)+ mRNA export from nucleus (inferred); PARTICIPATES IN NXF1-NXT1 export pathway; ASSOCIATED WITH Congenital A rthrogryposis with Anterior Horn Cell Disease (ortholog); genetic disease (ortholog); lethal congenital contracture syndrome 1 (ortholog); FOUND IN nuclear envelope (ortholog) | 9 | 55024673 | 55059297 | Dog | 30 | description | gene, protein-coding, MODEL [RefSeq] |
| 12375343 | NUP214 | nucleoporin 214 | ENCODES a protein that exhibits nuclear localization sequence binding (ortholog); INVOLVED IN mRNA export from nucleus (ortholog); protein export from nucleus (ortholog); protein import into nucleus (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; mRNA nuclear export pathwa y; NXF1-NXT1 export pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute myeloid leukemia (ortholog); brain disease (ortholog); FOUND IN nuclear envelope (ortholog) | 9 | 52840300 | 52943785 | Dog | 46 | description | gene, protein-coding, MODEL [RefSeq] |
| 12239036 | NXF1 | nuclear RNA export factor 1 | ENCODES a protein that exhibits mRNA binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN poly(A)+ mRNA export from nucleus (ortholog); RNA export from nucleus (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; ASSOCIATED W ITH intellectual disability (ortholog); FOUND IN cytoplasm (inferred); nuclear inclusion body (inferred); nuclear pore (inferred) | 18 | 53884512 | 53895168 | Dog | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 12382875 | SARNP | SAP domain containing ribonucleoprotein | ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); RNA binding (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; FOUND IN nuclear speck (infe rred); nucleus (inferred); transcription export complex (inferred) | 10 | 153682 | 203598 | Dog | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 12199503 | THOC1 | THO complex subunit 1 | ENCODES a protein that exhibits DNA binding (inferred); identical protein binding (inferred); RNA binding (inferred); INVOLVED IN apoptotic process (inferred); DNA-templated transcription (inferred); mRNA export from nucleus (inferred); PARTICIPATES IN NXF1-NXT1 export pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 86 (ortholog); FOUND IN chromosome, telomeric region (inferred); cytoplasm (inferred); nuclear matrix (inferred) | 7 | 67082100 | 67136592 | Dog | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 12116962 | THOC2 | THO complex subunit 2 | INVOLVED IN blastocyst development (ortholog); cell morphogenesis (ortholog); negative regulation of neuron projection development (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; ASSOCIATED WITH arthrogryposis multiplex congenita-7, X-linked (ortholog); ge netic disease (ortholog); immunodeficiency 127 (ortholog); FOUND IN chromosome, telomeric region (inferred); cytoplasm (inferred); nucleus (inferred) | X | 95087209 | 95217450 | Dog | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 12430740 | THOC5 | THO complex subunit 5 | INVOLVED IN blastocyst development (ortholog); cell morphogenesis (ortholog); negative regulation of macrophage differentiation (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; ASSOCIATED WITH anemia (ortholog); breast carcinoma (ortholog); leukopenia (orth olog); FOUND IN chromosome, telomeric region (inferred); nucleoplasm (inferred); nucleus (inferred) | 26 | 22748857 | 22785288 | Dog | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 12244409 | THOC6 | THO complex subunit 6 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN central nervous system development (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; ASSOCIATED WITH Beaulieu-Boycott-Innes Syndrome (ortholog); genetic disease (ortholog); FOUND IN chromoso me, telomeric region (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | 6 | 38161506 | 38164287 | Dog | 19 | description | gene, protein-coding, MODEL [RefSeq] |
| 12287125 | THOC7 | THO complex subunit 7 | INVOLVED IN mRNA export from nucleus (inferred); mRNA processing (inferred); PARTICIPATES IN NXF1-NXT1 export pathway; FOUND IN chromosome, telomeric region (inferred); cytoplasm (inferred); cytosol (inferred) | 20 | 27367628 | 27390868 | Dog | 19 | description | gene, protein-coding, MODEL [RefSeq] |