| 11965096 | MDM2 | MDM2 proto-oncogene | ENCODES a protein that exhibits p53 binding (ortholog); peroxisome proliferator activated receptor binding (ortholog); receptor serine/threonine kinase binding (ortholog); INVOLVED IN atrial septum development (ortholog); atrioventricular valve morphogenesis (ortholog); blood vessel development (ort holog); PARTICIPATES IN altered p53 signaling pathway; p53 signaling pathway; ASSOCIATED WITH Acute Experimental Pancreatitis (ortholog); acute myeloid leukemia (ortholog); biliary tract benign neoplasm (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density (ortholog) | 12 | 66322340 | 66357010 | Bonobo | 285 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12048500 | MTBP | MDM2 binding protein | INVOLVED IN negative regulation of cell population proliferation (ortholog); negative regulation of mitotic nuclear division (ortholog); protein localization to kinetochore (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); prostate cancer (ortholog); FOUND IN chromatin (inferred); kin etochore (inferred) | 8 | 117135172 | 117213360 | Bonobo | 14 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11753825 | CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | ENCODES a protein that exhibits cyclin binding (ortholog); MDM2/MDM4 family protein binding (ortholog); mitogen-activated protein kinase binding (ortholog); INVOLVED IN apoptotic nuclear changes (ortholog); cell population proliferation (ortholog); definitive er ythrocyte differentiation (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog) | 17 | 9556313 | 9567099 | Bonobo | 65 | description | gene, protein-coding, MODEL [RefSeq] |
| 11678663 | MARCHF7 | membrane associated ring-CH-type finger 7 | ENCODES a protein that exhibits enzyme binding (inferred); MDM2/MDM4 family protein binding (inferred); metal ion binding (inferred); INVOLVED IN negative regulation of T cell proliferation (ortholog); regulation of tolerance induction (ortholog); FOUND IN centr osome (inferred); cytoplasm (inferred); cytosol (inferred) | 2B | 47004211 | 47059901 | Bonobo | 33 | description | gene, protein-coding, MODEL [RefSeq] |
| 11757610 | PPARA | peroxisome proliferator activated receptor alpha | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); MDM2/MDM4 family protein binding (ortholog); mitogen-activated protein kinase kinase kinase binding (ortholog); INVOLVED IN behavioral response to nicotine (ortholog); cellular response to fructose stimulus (ortholog); enamel mineralization (ortholog); ASSOCIATED WITH abdominal obesity-metabolic syndrome (ortholog); acute kidney tubular necrosis (ortholog); alcohol use disorder (ortholog); FOUND IN nucleus (ortholog) | | | | Bonobo | 224 | description | gene, protein-coding, MODEL [RefSeq] |
| 11711406 | PSME3 | proteasome activator subunit 3 | ENCODES a protein that exhibits endopeptidase activator activity (inferred); identical protein binding (inferred); MDM2/MDM4 family protein binding (inferred); INVOLVED IN apoptotic process (inferred); negative regulation of extrinsic apoptotic signaling pathway (inferred); regulation of G1/S transition of mitotic cell cycle (inferred); ASSOCIATED WITH human immunodeficiency virus infectious disease (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); proteasome activator complex (inferred) | 17 | 14474604 | 14484522 | Bonobo | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 11765674 | RFWD3 | ring finger and WD repeat domain 3 | ENCODES a protein that exhibits MDM2/MDM4 family protein binding (inferred); metal ion binding (inferred); p53 binding (inferred); INVOLVED IN DNA damage response (inferred); DNA repair (inferred); double-strand break repair via homologous recombination (inferre d); ASSOCIATED WITH Fanconi anemia (ortholog); Fanconi anemia complementation group W (ortholog); Testicular Germ Cell Tumor (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred) | 16 | 55187178 | 55233265 | Bonobo | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 12011464 | RPL37 | ribosomal protein L37 | ENCODES a protein that exhibits MDM2/MDM4 family protein binding (inferred); metal ion binding (inferred); RNA binding (inferred); INVOLVED IN cytoplasmic translation (inferred); positive regulation of signal transduction by p53 class mediator (inferred); transl ation (inferred); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; FOUND IN cytoplasm (inferred); cytosolic large ribosomal subunit (inferred); cytosolic ribosome (inferred) | 5 | 69551852 | 69554735 | Bonobo | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 329330748 | RPS15 | ribosomal protein S15 | ENCODES a protein that exhibits MDM2/MDM4 family protein binding (ortholog); ubiquitin ligase inhibitor activity (ortholog); INVOLVED IN positive regulation of signal transduction by p53 class mediator (ortholog); ribosomal small subunit biogenesis (ortholog); r ibosomal small subunit export from nucleus (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytosolic ribosome (ortholog) | | | | Bonobo | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 11702101 | RPS20 | ribosomal protein S20 | ENCODES a protein that exhibits MDM2/MDM4 family protein binding (ortholog); ubiquitin ligase inhibitor activity (ortholog); INVOLVED IN positive regulation of signal transduction by p53 class mediator (ortholog); PARTICIPATES IN ribosome biogenesis pathway; tra nslation pathway; ASSOCIATED WITH Colorectal Cancer 10 (ortholog); Diamond-Blackfan anemia (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasmic side of rough endoplasmic reticulum membrane (ortholog); cytosol (ortholog); cytosolic ribosome (ortholog) | 8 | 52519658 | 52521152 | Bonobo | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 11772827 | TP53 | tumor protein p53 | ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); MDM2/MDM4 family protein binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); cellular response to heat (ortholog); cellul ar response to hypoxia (ortholog); PARTICIPATES IN altered p53 signaling pathway; endometrial cancer pathway; non-small cell lung carcinoma pathway; ASSOCIATED WITH Acute Erythroleukemia (ortholog); acute kidney failure (ortholog); acute lymphoblastic leukemia (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog); RNA polymerase II transcription regulator complex (ortholog) | 17 | 7699449 | 7717812 | Bonobo | 1150 | description | gene, protein-coding, MODEL [RefSeq] |