| 11927115 | INO80 | INO80 complex ATPase subunit | ENCODES a protein that exhibits actin binding (inferred); alpha-tubulin binding (inferred); ATP binding (inferred); INVOLVED IN cell division (inferred); cellular response to ionizing radiation (inferred); cellular response to UV (inferred); PARTICIPATES IN INO80 > family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); intellectual disability (ortholog); microcephaly (ortholog); FOUND IN chromosome (inferred); cytosol (inferred); Ino80 complex (inferred) | 15 | 19920980 | 20058117 | Bonobo | 76 | symbol , old_gene_name , name , description | gene, protein-coding, MODEL [RefSeq] |
| 11945105 | INO80B | INO80 complex subunit B | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 yle='font-weight:700;'>Ino80 complex (inferred); nuclear body (inferred); nucleolus (inferred) | 2A | 74521624 | 74524578 | Bonobo | 23 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 11803027 | INO80C | INO80 complex subunit C | INVOLVED IN chromatin remodeling (inferred); DNA-templated transcription (inferred); positive regulation of DNA repair (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN fibrillar center (inferred); Ino80 700;'>Ino80 complex (inferred); MLL1 complex (inferred) | 18 | 28686112 | 28715946 | Bonobo | 24 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 11926725 | INO80D | INO80 complex subunit D | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleus (inferred) | 2B | 93233672 | 93325871 | Bonobo | 14 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 11840977 | INO80E | INO80 complex subunit E | INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA-templated transcription (inferred); regulation of cell cycle (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH spondylocostal dysostosis 5 (orth olog); FOUND IN Ino80 complex (inferred); nucleolus (inferred); nucleoplasm (inferred) | | | | Bonobo | 21 | symbol , name , description | gene, protein-coding, MODEL [RefSeq] |
| 11944709 | ACTL6A | actin like 6A | ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN blastocyst formation (ortholog); chromatin remodeling (ortholog); spinal cord development (ortholog); PARTICIPATES IN altered SWI/SNF family mediated chromatin remodeling pathway; INO80 fa mily mediated chromatin remodeling pathway; pancreatic cancer pathway; ASSOCIATED WITH atrial heart septal defect (ortholog); cervical dystonia (ortholog); Developmental Disabilities (ortholog); FOUND IN Ino80 complex (inferred); npBAF complex (inferred); NuA4 histone acetyltransferase complex (inferred) | 3 | 176595149 | 176620556 | Bonobo | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 11982244 | ACTR5 | actin related protein 5 | INVOLVED IN positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); regulation of DNA repair (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoplas m (inferred); Ino80 complex (inferred); nucleus (inferred) | 20 | 35073297 | 35097955 | Bonobo | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 11691661 | ACTR8 | actin related protein 8 | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN cell division (inferred); chromatin remodeling (inferred); DNA damage response (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUN D IN chromosome (inferred); Ino80 complex (inferred); nucleoplasm (inferred) | 3 | 53802916 | 53820244 | Bonobo | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 11848766 | NFRKB | nuclear factor related to kappaB binding protein | ENCODES a protein that exhibits DNA binding (inferred); protease binding (inferred); INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA repair (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN INO80 f amily mediated chromatin remodeling pathway; FOUND IN Ino80 complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 11 | 124676456 | 124708349 | Bonobo | 25 | description | gene, protein-coding, MODEL [RefSeq] |
| 329331335 | ACTB | actin beta | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); identical protein binding (ortholog); kinesin binding (ortholog); INVOLVED IN adherens junction assembly (ortholog); apical protein localization (ortholog); axonogenesis (ortholog); PARTICIPATES IN auditory mechanotransduction pathw ay; INO80 family mediated chromatin remodeling pathway; mitochondria transport pathway; ASSOCIATED WITH Aminoacylase 1 Deficiency (ortholog); Animal Mammary Neoplasms (ortholog); Baraitser-Winter syndrome (ortholog); FOUND IN actin cytoskeleton (ortholog); adherens junction (ortholog); apical junction complex (ortholog) | | | | Bonobo | 173 | description | gene, protein-coding, MODEL [RefSeq] |
| 11952825 | ACTR6 | actin related protein 6 | INVOLVED IN DNA-templated transcription (inferred); nucleolus organization (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN cytoskeleton (inferred); nucleolus (inferred); nucleus (inferred) | 12 | 97781017 | 97806049 | Bonobo | 11 | description | gene, protein-coding, MODEL [RefSeq] |
| 11800786 | BRD8 | bromodomain containing 8 | ENCODES a protein that exhibits nuclear thyroid hormone receptor binding (inferred); transcription coactivator activity (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH colorectal adenocarcinoma (ortholog); endometriosis (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 5 | 133535321 | 133557304 | Bonobo | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 12038937 | DMAP1 | DNA methyltransferase 1 associated protein 1 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (inferred); transcription corepressor activity (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); response to ethanol (ortholog); PARTICIPATES IN INO80 ='font-weight:700;'>INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); Muscle Hypotonia (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); cytosol (inferred) | 1 | 43516839 | 43524206 | Bonobo | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 11984990 | EPC1 | enhancer of polycomb homolog 1 | ENCODES a protein that exhibits chromatin-protein adaptor activity (inferred); enzyme-substrate adaptor activity (inferred); INVOLVED IN negative regulation of gene expression, epigenetic (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcr iption by RNA polymerase II (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neointima (ortholog); FOUND IN histone acetyltransferase complex (inferred); NuA4 histone acetyltransferase complex (inferred); nuclear body (inferred) | 10 | 32398557 | 32509146 | Bonobo | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 11975114 | EPC2 | enhancer of polycomb 2 | INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); positive regulation of double-strand break repair via homologous recombination (inferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH type 2 diabetes mellitus (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleus (inferred) | 2B | 11074397 | 11218181 | Bonobo | 10 | description | gene, protein-coding, MODEL [RefSeq] |
| 11887681 | ING3 | inhibitor of growth family member 3 | ENCODES a protein that exhibits histone H2A acetyltransferase activity (inferred); histone H3K4me3 reader activity (inferred); histone H4 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (inferred); PAR TICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 7 | 112955848 | 112984473 | Bonobo | 26 | description | gene, protein-coding, MODEL [RefSeq] |
| 12047555 | KAT5 | lysine acetyltransferase 5 | ENCODES a protein that exhibits chromatin binding (ortholog); phospholipase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to X-ray (ortholog); lipid droplet disassembly (ortholog); PARTICIPATES IN a taxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); breast cancer (ortholog); iron deficiency anemia (ortholog); FOUND IN chromatin (ortholog); protein-containing complex (ortholog) | 11 | 61071118 | 61078667 | Bonobo | 157 | description | gene, protein-coding, MODEL [RefSeq] |
| 11986976 | LOC100971447 | E1A-binding protein p400 | ENCODES a protein that exhibits chromatin binding (ortholog); protein antigen binding (ortholog); INVOLVED IN gene expression (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN nuclear speck (ortholog) | 12 | 129606823 | 129737179 | Bonobo | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 11860099 | MCRS1 | microspherule protein 1 | ENCODES a protein that exhibits telomerase inhibitor activity (ortholog); INVOLVED IN negative regulation of telomere maintenance via telomere lengthening (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN dendrite (ortholog ); perikaryon (ortholog) | 12 | 39183112 | 39192925 | Bonobo | 61 | description | gene, protein-coding, MODEL [RefSeq] |
| 11727694 | MEAF6 | MYST/Esa1 associated factor 6 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (inferred); histone H4K12 acetyltransferase activity (inferred); histone H4K5 acetyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA-templated transcription (i nferred); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN histone acetyltransferase complex (inferred); kinetochore (inferred); MOZ/MORF histone acetyltransferase complex (inferred) | 1 | 36761402 | 36783746 | Bonobo | 34 | description | gene, protein-coding, MODEL [RefSeq] |
| 11821015 | MORF4L1 | mortality factor 4 like 1 | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN cell population proliferation (ortholog); double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chr omatin remodeling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); FOUND IN nuclear speck (ortholog); Sin3-type complex (ortholog) | 15 | 57844220 | 57869139 | Bonobo | 41 | description | gene, protein-coding, MODEL [RefSeq] |
| 12045232 | MORF4L2 | mortality factor 4 like 2 | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); positive regulation of striated muscle cell differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN INO80 pan> family mediated chromatin remodeling pathway; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog) | X | 92904721 | 92917340 | Bonobo | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 11717182 | MRGBP | MRG domain binding protein | INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH neuronal ceroid lipofuscinosis (orthol og); FOUND IN nucleoplasm (ortholog) | 20 | 59183842 | 59187982 | Bonobo | 12 | description | gene, protein-coding, MODEL [RefSeq] |
| 11960172 | RUVBL1 | RuvB like AAA ATPase 1 | ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of plasminogen activation (ortholog); regulation of fibroblast apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear matrix (ortholog); protein-containing complex (ortholog) | 3 | 125120524 | 125200859 | Bonobo | 76 | description | gene, protein-coding, MODEL [RefSeq] |
| 11797306 | RUVBL2 | RuvB like AAA ATPase 2 | ENCODES a protein that exhibits ADP binding (ortholog); ATPase binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of DNA repair (ortholog); positive regulation of telomere maintenance in response to DNA damage (ortholog); PAR TICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN ribonucleoprotein complex (ortholog) | 19 | 45995394 | 46017835 | Bonobo | 83 | description | gene, protein-coding, MODEL [RefSeq] |
| 11755608 | SRCAP | Snf2 related CREBBP activator protein | ENCODES a protein that exhibits ATP-dependent chromatin remodeler activity (ortholog); INVOLVED IN cAMP/PKA signal transduction (inferred); chromatin organization (inferred); chromatin remodeling (inferred); PARTICIPATES IN INO80 family mediated chromatin remode ling pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); adenoid cystic carcinoma (ortholog); autism spectrum disorder (ortholog); FOUND IN nucleus (ortholog) | 16 | 24229869 | 24271427 | Bonobo | 50 | description | gene, protein-coding, MODEL [RefSeq] |
| 11716786 | TFPT | TCF3 fusion partner | ENCODES a protein that exhibits protein kinase binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN actin filament (ortholog); cytoplasm (ortholog) | 19 | 51039142 | 51048346 | Bonobo | 40 | description | gene, protein-coding, MODEL [RefSeq] |
| 11810276 | TRRAP | transformation/transcription domain associated protein | ENCODES a protein that exhibits chromatin binding (ortholog); transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); regu lation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 75 (ortholog); Developmental Delay with or without Dysmorphic Facies and Autism (ortholog); Developmental Disabilities (ortholog); FOUND IN Swr1 complex (ortholog); transcription factor TFTC complex (ortholog); transcription regulator complex (ortholog) | 7 | 90845518 | 90981700 | Bonobo | 36 | description | gene, protein-coding, MODEL [RefSeq] |
| 11904828 | UCHL5 | ubiquitin C-terminal hydrolase L5 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); endopeptidase inhibitor activity (inferred); INVOLVED IN regulation of AMPA receptor activity (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH alcohol-associated liver disease (ortholog); Experimental Diabetes Mellitus (ortholog); Testis Reperfusion Injury (ortholog); FOUND IN cytosolic proteasome complex (ortholog); synaptic vesicle (ortholog) | 1 | 168471501 | 168519366 | Bonobo | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 11902534 | VPS72 | vacuolar protein sorting 72 homolog | ENCODES a protein that exhibits histone binding (inferred); histone chaperone activity (inferred); INVOLVED IN somatic stem cell population maintenance (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear speck (inferr ed); nucleus (inferred); protein-containing complex (inferred) | 1 | 126525642 | 126539432 | Bonobo | 14 | description | gene, protein-coding, MODEL [RefSeq] |
| 12041554 | YEATS4 | YEATS domain containing 4 | ENCODES a protein that exhibits histone H3K18ac reader activity (inferred); histone H3K27ac reader activity (inferred); INVOLVED IN gene expression (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH high grade glioma (ortholog); liposarcoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 12 | 66881733 | 66912966 | Bonobo | 23 | description | gene, protein-coding, MODEL [RefSeq] |
| 11913701 | YY1 | YY1 transcription factor | ENCODES a protein that exhibits chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); B cell differentiation (ortholog); camera-type eye morphogenesis (ortholog); PARTICIP ATES IN INO80 family mediated chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); congestive heart failure (ortholog); developmental and epileptic encephalopathy 78 (ortholog); FOUND IN chromatin (ortholog); chromatin silencing complex (ortholog); fibrillar center (ortholog) | 14 | 80859491 | 80903651 | Bonobo | 129 | description | gene, protein-coding, MODEL [RefSeq] |
| 11790110 | YY1AP1 | YY1 associated protein 1 | ENCODES a protein that exhibits transcription coregulator activity (inferred); INVOLVED IN cell differentiation (inferred); cell population proliferation (inferred); DNA-templated transcription (inferred); ASSOCIATED WITH genetic disease (ortholog); Grange Syndrome (ortholog); intellectual disabilit y (ortholog); FOUND IN Ino80 complex (inferred); nucleolus (inferred); nucleoplasm (inferred) | 1 | 130995949 | 131024985 | Bonobo | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 11981254 | ZNHIT1 | zinc finger HIT-type containing 1 | ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); histone deacetylase binding (inferred); INVOLVED IN negative regulation of G0 to G1 transition (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); regulation of T cell proliferatio n (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; p53 signaling pathway; FOUND IN nucleus (inferred) | 7 | 93359038 | 93365521 | Bonobo | 35 | description | gene, protein-coding, MODEL [RefSeq] |