| 8941692 | Osm | oncostatin M | ENCODES a protein that exhibits cytokine activity (ortholog); growth factor activity (ortholog); oncostatin-M receptor binding (ortholog); INVOLVED IN behavioral response to pain (ortholog); negative regulation of hormone secretion (ortholog); negative regulation of meiotic nuclear division (ortholo g); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; interleukin-3 signaling pathway; ASSOCIATED WITH Chloracne (ortholog); contact dermatitis (ortholog); COVID-19 (ortholog) | NW_004955455 | 4510711 | 4515282 | Chinchilla | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 8923033 | Osmr | oncostatin M receptor | ENCODES a protein that exhibits cytokine binding (ortholog); growth factor binding (ortholog); oncostatin-M receptor activity (ortholog); INVOLVED IN oncostatin-M-mediated signaling pathway (ortholog); positive regulation of cell population proliferation (ortholog); response to cytokine (ortholog); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN apical plasma membrane (ortholog); external side of plasma membrane (ortholog); oncostatin-M receptor complex (ortholog) | NW_004955426 | 23395286 | 23465078 | Chinchilla | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 8723832 | Ddx3x | DEAD-box helicase 3 X-linked | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); CTPase activity (ortholog); DNA binding (ortholog); INVOLVED IN cellular response to arsenic-containing substance (ortholog); cellular response to osmotic stress (ortholog); cellular response to virus (ortholog); ASSOCIATED WITH autistic disorder (ortholog); breast cancer (ortholog); cerebellar hypoplasia (ortholog); FOUND IN cell leading edge (ortholog); centrosome (ortholog); cytoplasm (ortholog) | NW_004955565 | 1387043 | 1403624 | Chinchilla | 153 | description | gene, protein-coding, MODEL [RefSeq] |
| 9020311 | Dysf | dysferlin | ENCODES a protein that exhibits alpha-tubulin binding (ortholog); calcium ion binding (ortholog); calcium-dependent phospholipid binding (ortholog); INVOLVED IN angiogenesis (ortholog); cellular response to osmotic stress (ortholog); fat cell differentiation (or tholog); ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy (ortholog); autosomal recessive limb-girdle muscular dystrophy type 2B (ortholog); autosomal recessive nonsyndromic deafness (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); early endosome (ortholog) | NW_004955424 | 13756130 | 13970437 | Chinchilla | 85 | description | gene, protein-coding, MODEL [RefSeq] |
| 8775019 | Lrrc8c | leucine rich repeat containing 8 VRAC subunit C | ENCODES a protein that exhibits volume-sensitive anion channel activity (ortholog); INVOLVED IN aspartate transmembrane transport (ortholog); cellular response to osmotic stress (ortholog); cyclic-GMP-AMP transmembrane import across plasma membrane (ortholog); A SSOCIATED WITH multiple sclerosis (ortholog); TIMES Syndrome (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); monoatomic ion channel complex (ortholog) | NW_004955423 | 4460212 | 4494317 | Chinchilla | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 8808000 | Lrrc8d | leucine rich repeat containing 8 VRAC subunit D | ENCODES a protein that exhibits volume-sensitive anion channel activity (ortholog); INVOLVED IN aspartate transmembrane transport (ortholog); cellular response to osmotic stress (ortholog); cyclic-GMP-AMP transmembrane import across plasma membrane (ortholog); F OUND IN cytoplasm (ortholog); membrane (ortholog); monoatomic ion channel complex (ortholog) | NW_004955423 | 4237263 | 4360352 | Chinchilla | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 8740610 | Lrrc8e | leucine rich repeat containing 8 VRAC subunit E | ENCODES a protein that exhibits volume-sensitive anion channel activity (ortholog); INVOLVED IN aspartate transmembrane transport (ortholog); cell volume homeostasis (ortholog); cellular response to osmotic stress (ortholog); ASSOCIATED WITH long QT syndrome (or tholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum membrane (ortholog); lysosomal membrane (ortholog) | NW_004955563 | 1362266 | 1370221 | Chinchilla | 19 | description | gene, protein-coding, MODEL [RefSeq] |
| 8834847 | Map2k7 | mitogen-activated protein kinase kinase 7 | ENCODES a protein that exhibits ATP binding (ortholog); enzyme binding (ortholog); JUN kinase kinase activity (ortholog); INVOLVED IN cellular response to interleukin-1 (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to osmotic stress (ortholog); PARTICIPATES IN adenosine signaling pathway; c-Jun N-terminal kinases MAPK signaling pathway; FasL mediated signaling pathway; ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); colon adenocarcinoma (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | NW_004955563 | 1352638 | 1361598 | Chinchilla | 92 | description | gene, protein-coding, MODEL [RefSeq] |
| 8878633 | Nlk | nemo like kinase | ENCODES a protein that exhibits ATP binding (ortholog); DNA-binding transcription factor binding (ortholog); magnesium ion binding (ortholog); INVOLVED IN cellular response to osmotic stress (ortholog); intracellular signal transduction (ortholog); negative regu lation of TORC1 signaling (ortholog); PARTICIPATES IN Wnt signaling, non-canonical pathway; ASSOCIATED WITH myocardial infarction (ortholog); Spinal Cord Injuries (ortholog); Subarachnoid Hemorrhage (ortholog); FOUND IN nucleus (ortholog) | NW_004955481 | 4828441 | 4973734 | Chinchilla | 38 | description | gene, protein-coding, MODEL [RefSeq] |
| 9056084 | Relb | RELB proto-oncogene, NF-kB subunit | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); identical protein binding (ortholog); INVOLVED IN antigen processing and presentation (ortholog); cellular response to osmotic stress (ortholog); circad ian regulation of gene expression (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); atopic dermatitis (ortholog); breast cancer (ortholog); FOUND IN centrosome (ortholog); chromatin (ortholog); cytosol (ortholog) | NW_004955555 | 2060533 | 2086229 | Chinchilla | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 8883751 | Scn7a | sodium voltage-gated channel alpha subunit 7 | ENCODES a protein that exhibits osmolarity-sensing monoatomic cation channel activity (ortholog); sodium channel activity (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN membrane depolarization during action potential (ortholog); neuronal a ction potential (ortholog); osmosensory signaling pathway (ortholog); ASSOCIATED WITH autistic disorder (ortholog); brain infarction (ortholog); FOUND IN glial cell projection (ortholog); plasma membrane (ortholog); voltage-gated sodium channel complex (ortholog) | NW_004955449 | 7714424 | 7798383 | Chinchilla | 22 | description | gene, protein-coding, MODEL [RefSeq] |
| 8808130 | Tmem63c | transmembrane protein 63C | ENCODES a protein that exhibits calcium-activated cation channel activity (ortholog); osmolarity-sensing monoatomic cation channel activity (ortholog); phospholipid scramblase activity (ortholog); INVOLVED IN glomerular filtration (ortholog); monoatomic cation t ransport (ortholog); ASSOCIATED WITH Albuminuria (ortholog); focal segmental glomerulosclerosis (ortholog); hereditary spastic paraplegia 87 (ortholog); FOUND IN lysosomal membrane (ortholog); plasma membrane (ortholog) | NW_004955438 | 1091324 | 1155878 | Chinchilla | 13 | description | gene, protein-coding, MODEL [RefSeq] |
| 8706237 | Tsc22d2 | TSC22 domain family member 2 | INVOLVED IN negative regulation of cell cycle (ortholog); response to osmotic stress (ortholog); ASSOCIATED WITH keratoconus (ortholog) | NW_004955448 | 1639463 | 1678279 | Chinchilla | 6 | description | gene, protein-coding, MODEL [RefSeq] |
| 8975726 | Zfand1 | zinc finger AN1-type containing 1 | ENCODES a protein that exhibits proteasome binding (ortholog); INVOLVED IN cellular response to arsenite ion (ortholog); cellular response to heat (ortholog); cellular response to osmotic stress (ortholog); FOUND IN cytoplasmic stress granule (ortholog) | NW_004955417 | 51721 | 88488 | Chinchilla | 9 | description | gene, protein-coding, MODEL [RefSeq] |