| 8789629 | Erbb2 | erb-b2 receptor tyrosine kinase 2 | ENCODES a protein that exhibits coreceptor activity (ortholog); ErbB-3 class receptor binding (ortholog); growth factor binding (ortholog); INVOLVED IN axon regeneration (ortholog); cell population proliferation (ortholog); cell surface receptor protein tyrosine kinase signaling pathway (ortholog); PARTICIPATES IN altered epidermal growth factor/neuregulin signaling pathway; endometrial cancer pathway; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); amblyopia (ortholog); Animal Disease Models (ortholog); FOUND IN cell projection; apical plasma membrane (ortholog); basal plasma membrane (ortholog) | NW_004955451 | 14442816 | 14456009 | Chinchilla | 299 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 8954174 | Tob1 | transducer of ERBB2, 1 | ENCODES a protein that exhibits receptor tyrosine kinase binding (ortholog); SMAD binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN negative regulation of BMP signaling pathway (ortholog); negative regulation of cell population proliferation (ortholog); negative regulati on of nuclear-transcribed mRNA poly(A) tail shortening (ortholog); ASSOCIATED WITH Chloracne (ortholog); endometriosis (ortholog); Experimental Neoplasms (ortholog); FOUND IN CCR4-NOT complex (ortholog); cytoplasm (ortholog) | NW_004955451 | 10950270 | 10963183 | Chinchilla | 27 | name | gene, protein-coding, MODEL [RefSeq] |
| 39131546 | TOB1 | transducer of ERBB2, 1 | | | | | Chinchilla | | name | gene, protein-coding |
| 9050621 | Tob2 | transducer of ERBB2, 2 | ENCODES a protein that exhibits nuclear vitamin D receptor binding (ortholog); INVOLVED IN negative regulation of osteoclast differentiation (ortholog); positive regulation of ossification (ortholog); regulation of gene expression (ortholog); ASSOCIATED WITH vitiligo (ortholog) | NW_004955413 | 26999955 | 27010091 | Chinchilla | 10 | name | gene, protein-coding, MODEL [RefSeq] |
| 9049882 | Erbin | erbb2 interacting protein | ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN cellular response to tumor necrosis factor (ortholog); negative regulation of monocyte chemotactic protein-1 production (ortholog); negative regulation of nucleotide-binding oligomerization domain containing 2 signali ng pathway (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); prostate cancer (ortholog); FOUND IN basolateral plasma membrane (ortholog); cell junction (ortholog); cytoplasm (ortholog) | NW_004955446 | 3046268 | 3151796 | Chinchilla | 35 | name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 9059226 | Btc | betacellulin | ENCODES a protein that exhibits epidermal growth factor receptor binding (ortholog); growth factor activity (ortholog); receptor ligand activity (ortholog); INVOLVED IN epidermal growth factor receptor signaling pathway (ortholog); ERBB2-EGFR signaling pathway ( ortholog); ERBB4-ERBB4 signaling pathway (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH erythropoietic protoporphyria (ortholog); Experimental Diabetes Mellitus (ortholog); Glucagonoma (ortholog); FOUND IN extracellular space (ortholog) | NW_004955474 | 895573 | 946152 | Chinchilla | 39 | description | gene, protein-coding, MODEL [RefSeq] |
| 8929914 | Cpne3 | copine 3 | ENCODES a protein that exhibits calcium-dependent phospholipid binding (ortholog); calcium-dependent protein binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cellular response to calcium ion (ortholog); cellular response to growth factor stimulus (ortholog); ERBB2 style='font-weight:700;'>ERBB2 signaling pathway (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cell junction (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955417 | 4115298 | 4146878 | Chinchilla | 18 | description | gene, protein-coding, MODEL [RefSeq] |
| 8948702 | Map2k2 | mitogen-activated protein kinase kinase 2 | ENCODES a protein that exhibits ATP binding (ortholog); MAP kinase kinase activity (ortholog); MAP-kinase scaffold activity (ortholog); INVOLVED IN epithelial cell proliferation involved in lung morphogenesis (ortholog); ERBB2-ERBB3 signaling pathway (ortholog); ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN adenosine signaling pathway; ceramide signaling pathway; endothelin signaling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); breast cancer (ortholog); cardiofaciocutaneous syndrome (ortholog); FOUND IN cell cortex (ortholog); cell-cell junction (ortholog); cytoplasm (ortholog) | NW_004955495 | 4695239 | 4718380 | Chinchilla | 110 | description | gene, protein-coding, MODEL [RefSeq] |
| 8813137 | Nrg2 | neuregulin 2 | ENCODES a protein that exhibits epidermal growth factor receptor activity (ortholog); epidermal growth factor receptor binding (ortholog); ErbB-3 class receptor binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); epidermal growth factor receptor signaling pathway (ort holog); ERBB2-ERBB3 signaling pathway (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN extracellular space (ortholog); GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog) | NW_004955418 | 548624 | 793861 | Chinchilla | 29 | description | gene, protein-coding, MODEL [RefSeq] |
| 8854175 | Ptprr | protein tyrosine phosphatase receptor type R | ENCODES a protein that exhibits protein kinase binding (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN ERBB2 signaling pathway (ortholog); in utero embryonic development (ortholog); negative regulation of epithelial cell migration (orth olog); FOUND IN cell junction (ortholog); cytosol (ortholog); plasma membrane (ortholog) | NW_004955405 | 10767548 | 11133695 | Chinchilla | 22 | description | gene, protein-coding, MODEL [RefSeq] |