| 1558494 | Usp4 | ubiquitin specific peptidase 4 | Predicted to enable adenosine receptor binding activity; cysteine-type deubiquitinase activity; and identical protein binding activity. Predicted to be involved in several processes, including positive regulation of TORC1 signaling; protein localization to cell surface; and spliceosomal tri-snRNP co mplex assembly. Predicted to be located in cytosol and plasma membrane. Predicted to be active in nucleus. Is expressed in facial prominence ectoderm and facial prominence mesenchyme. Orthologous to human USP4 (ubiquitin specific peptidase 4). [provided by Alliance of Genome Resources, Apr 2025] | 9 | 108223763 | 108269744 | Mouse | 140 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1320046 | Usp40 | ubiquitin specific peptidase 40 | Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of protein stability. Predicted to be active in cytosol and nucleus. Orthologous to human USP40 (ubiquitin specific peptidase 40). [provided by Alliance of Genome R esources, Jul 2025] | 1 | 87872841 | 87936308 | Mouse | 81 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1623119 | Usp42 | ubiquitin specific peptidase 42 | Enables cysteine-type deubiquitinase activity. Involved in protein deubiquitination. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including brain; eye; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human USP4 USP42 (ubiquitin specific peptidase 42). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 143696077 | 143741600 | Mouse | 93 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1317759 | Usp43 | ubiquitin specific peptidase 43 | Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination and proteolysis. Orthologous to human USP43 (ubiquitin specific peptidase 43). [provided by Alliance of Genome Resources, Apr 2025] | 11 | 67745349 | 67812979 | Mouse | 89 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1622843 | Usp44 | ubiquitin specific peptidase 44 | Predicted to enable cysteine-type deubiquitinase activity. Involved in chromosome segregation; proteasome-mediated ubiquitin-dependent protein catabolic process; and regulation of mitotic cell cycle spindle assembly checkpoint. Located in nucleus. Orthologous to human USP4 USP44 (ubiquitin specific peptidase 44). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 93655831 | 93696792 | Mouse | 105 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1551688 | Usp45 | ubiquitin specific petidase 45 | Predicted to enable cysteine-type deubiquitinase activity. Involved in photoreceptor cell maintenance. Predicted to be located in cytosol; nucleoplasm; and photoreceptor inner segment. Used to study Leber congenital amaurosis 19. Human ortholog(s) of this gene implicated in Leber congenital amaurosi s 19. Orthologous to human USP45 (ubiquitin specific peptidase 45). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 21767161 | 21837872 | Mouse | 115 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1557334 | Usp46 | ubiquitin specific peptidase 46 | Enables deubiquitinase activity. Involved in regulation of GABAergic synaptic transmission. Acts upstream of or within several processes, including adult feeding behavior; behavioral fear response; and behavioral response to ethanol. Predicted to be located in cytoplasm. Predicted to be active in cy tosol; glutamatergic synapse; and nucleus. Is expressed in cerebral cortex intermediate zone; cortical plate; and pancreas epithelium. Orthologous to human USP46 (ubiquitin specific peptidase 46). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 74159387 | 74229070 | Mouse | 122 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1553480 | Usp47 | ubiquitin specific peptidase 47 | Predicted to enable WD40-repeat domain binding activity and cysteine-type deubiquitinase activity. Acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Predicted to be located in cytoplasm. Predicted to be part of SCF ubiquitin ligase com plex. Predicted to be active in cytosol and nucleus. Orthologous to human USP47 (ubiquitin specific peptidase 47). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 111622692 | 111710591 | Mouse | 143 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1551945 | Usp48 | ubiquitin specific peptidase 48 | Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of protein stability. Predicted to be located in mitochondrion; nucleoplasm; and postsynaptic membrane. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including germ cell of testis; intestine; liver and biliary system; salivary gland; and thymus. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 85. Orthologous to human USP48 (ubiquitin specific peptidase 48). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 137321079 | 137385842 | Mouse | 89 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1614183 | Usp49 | ubiquitin specific peptidase 49 | Predicted to enable histone binding activity and peptidase activity. Predicted to be involved in mRNA splicing, via spliceosome and negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is e xpressed in cerebral cortex subventricular zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human USP49 (ubiquitin specific peptidase 49). [provided by Alliance of Genome Resources, Apr 2025] | 17 | 47941615 | 47997664 | Mouse | 119 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1613071 | Usp46os1 | ubiquitin specific peptidase 46, opposite strand 1 | | 5 | 74174648 | 74175996 | Mouse | 3 | symbol , old_gene_name , PhenoGen | gene, ncrna, MODEL [RefSeq] |
| 1609259 | Usp46os2 | ubiquitin specific peptidase 46, opposite strand 2 | INTERACTS WITH sodium fluoride | | | | Mouse | 4 | symbol , PhenoGen | gene, ncrna |
| 13702997 | Gm20517 | predicted gene 20517 | This locus represents naturally-occurring readthrough transcription between the neighboring mediator complex subunit 20 (Med20) and ubiquitin specific peptidase 49 (Usp49) genes. Readthrough transcripts may be candidates for nonsense mediated decay (NMD) or enco de proteins with similarity to the Med20 gene. [provided by RefSeq, Jul 2018] | 17 | 47922510 | 47997664 | Mouse | | old_gene_name , description | gene, protein-coding, VALIDATED [RefSeq] |