| 1557076 | Ulk1 | unc-51 like kinase 1 | Enables Hsp90 protein binding activity; protein kinase binding activity; and protein serine/threonine kinase activity. Involved in several processes, including cellular response to amino acid starvation; macroautophagy; and response to mitochondrial depolarisation. Acts upstream of or within several processes, including Ras protein signal transduction; generation of neurons; and radial glia guided migration of cerebellar granule cell. Located in several cellular components, including cytoplasmic vesicle membrane; neuronal cell body; and phagophore assembly site membrane. Part of Atg1/ULK1 kinase complex. Is expressed in several structures, including central nervous system; dorsal root ganglion; heart; retina; and tibialis anterior. Orthologous to human ULK1 (unc-51 like autophagy activating kinase 1). [provided by Alliance of Genome Resources, Apr 2025] | 5 | 110932355 | 110957991 | Mouse | 403 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1332180 | Atg13 | autophagy related 13 | Predicted to enable protein kinase binding activity and protein serine/threonine kinase activator activity. Involved in several processes, including macroautophagy; positive regulation of autophagy; and response to mitochondrial depolarisation. Located in cytosol and phagophore assembly site. Part o f Atg1/ULK1 kinase complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and respiratory system. Orthologous to human ATG13 (autophagy related 13). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 91504957 | 91540947 | Mouse | 130 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1319645 | Rb1cc1 | RB1-inducible coiled-coil 1 | Enables protein kinase binding activity. Involved in autophagosome assembly; negative regulation of cell population proliferation; and positive regulation of autophagy. Acts upstream of or within several processes, including defense response to other organism; positive regulation of cell size; and r egulation of signal transduction. Located in autophagosome membrane; nucleus; and phagophore assembly site membrane. Part of Atg1/ULK1 kinase complex. Is expressed in several structures, including cerebral cortex; ganglia; musculoskeletal system; oocyte; and trunk paraxial mesenchyme. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human RB1CC1 (RB1 inducible coiled-coil 1). [provided by Alliance of Genome Resources, Apr 2025] | 1 | 6284858 | 6346599 | Mouse | 255 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1321048 | Tbc1d5 | TBC1 domain family, member 5 | Predicted to enable AP-2 adaptor complex binding activity; GTPase activator activity; and retromer complex binding activity. Predicted to be involved in several processes, including macroautophagy; positive regulation of receptor internalization; and retrograde transport, endosome to Golgi. Predicte d to be located in autophagosome. Predicted to be part of AP-2 adaptor complex; Atg1/ULK1 kinase complex; and retromer complex. Predicted to be active in Golgi apparatus and endosome membrane. Orthologous to human TBC1D5 (TBC1 domain family member 5). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 51040155 | 51488228 | Mouse | 130 | description | gene, protein-coding, VALIDATED [RefSeq] |