Predicted to enable several functions, including mitogen-activated protein kinase kinase kinase binding activity; protein homodimerization activity; and transcription coactivator activity. Involved in host-mediated suppression of symbiont invasion; negative regulation of viral transcription; and sup
pression of viral release by host. Acts upstream of or within positive regulation of protein localization to nucleus and stem cell population maintenance. Located in cytosol and nucleus. Is expressed in several structures, including central nervous system; female reproductive system; and urinary system. Orthologous to human TRIM8 (tripartite motif containing 8). [provided by Alliance of Genome Resources, Jul 2025]