Predicted to enable identical protein binding activity and thyrotropin-releasing hormone receptor activity. Predicted to be involved in phospholipase C-activating G protein-coupled receptor signaling pathway; positive regulation of cytosolic calcium ion concentration; and positive regulation of prot
ein-containing complex assembly. Predicted to be located in cell surface. Is expressed in several structures, including alimentary system; brain; heart; sensory organ; and skeleton. Used to study congenital hypothyroidism. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 7 and hypertension. Orthologous to human TRHR (thyrotropin releasing hormone receptor). [provided by Alliance of Genome Resources, Jul 2025]
Predicted to enable thyrotropin-releasing hormone receptor activity. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in neuronal cell body and plasma membrane. Is expressed in brain; cap mesenchyme; embryo; and female associ
Enables identical protein binding activity and neuropeptide receptor activity. Involved in G protein-coupled receptor signaling pathway. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Is expressed in seve
ral structures, including ileum; liver; male reproductive gland or organ; nervous system; and spleen. Orthologous to human GPR139 (G protein-coupled receptor 139). [provided by Alliance of Genome Resources, Apr 2025]