Traf6 Gene Search Result

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2 records found for search term Traf6

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1315707	Traf6	TNF receptor-associated factor 6	This gene encodes a member of the TNF receptor associated factor (TRAF) family of adaptor proteins that mediate signaling events from members of the TNF receptor and Toll/IL-1 receptor families to activate transcription factors such as NF-kappa-B and AP-1. The product of this gene is essential for p ... (more) erinatal and postnatal survival. Mice deficient in this protein exhibit osteopetrosis and defective in development of epidermal appendixes, normal B cell differentiation, lymph node organogenesis, interleukin-1 signaling, lipopolysaccharide signaling and neural tube closure. This protein possesses ubiquitin ligase activity. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]	2	101508765	101532013	Mouse	552	symbol , old_gene_name , PhenoGen	gene, protein-coding, REVIEWED [RefSeq]
732526	Tax1bp1	Tax1 (human T cell leukemia virus type I) binding protein 1	Enables kinase binding activity. Involved in negative regulation of NF-kappaB transcription factor activity. Predicted to be located in autophagosome; cytoplasmic vesicle; and phagophore assembly site. Predicted to be active in mitochondrion. Is expressed in central nervous system; genital tubercle; ... (more) limb mesenchyme; and retina nuclear layer. Orthologous to human TAX1BP1 (Tax1 binding protein 1). [provided by Alliance of Genome Resources, Apr 2025]	6	52690677	52743765	Mouse	166	old_gene_name	gene, protein-coding, VALIDATED [RefSeq]