Ror2 Gene Search Result

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2 records found for search term Ror2

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1313208	Ror2	receptor tyrosine kinase-like orphan receptor 2	Enables Wnt-protein binding activity; frizzled binding activity; and mitogen-activated protein kinase kinase kinase binding activity. Involved in positive regulation of DNA-templated transcription and positive regulation of canonical Wnt signaling pathway. Acts upstream of or within several processe ... (more) s, including cartilage development; cell surface receptor signaling pathway; and embryonic morphogenesis. Predicted to be located in several cellular components, including cell surface; microtubule; and neuronal cell body. Predicted to be part of receptor complex. Predicted to be active in several cellular components, including axon; glutamatergic synapse; and postsynapse. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Used to study autosomal recessive Robinow syndrome. Human ortholog(s) of this gene implicated in autosomal recessive Robinow syndrome; brachydactyly type B1; and cleft palate. Orthologous to human ROR2 (receptor tyrosine kinase like orphan receptor 2). [provided by Alliance of Genome Resources, Jul 2025]	13	53263353	53440160	Mouse	361	symbol , old_gene_name , PhenoGen , description , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1318176	Rora	RAR-related orphan receptor alpha	The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nu ... (more) cleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]	9	68560627	69295528	Mouse	496	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]