Ripk1 Gene Search Result

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Genes search result for Mus musculus
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2 records found for search term Ripk1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1320897	Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	Enables protein homodimerization activity; protein serine/threonine kinase activity; and signaling adaptor activity. Involved in several processes, including necroptotic signaling pathway; negative regulation of necroptotic process; and regulation of signal transduction. Acts upstream of or within s ... (more) everal processes, including negative regulation of canonical NF-kappaB signal transduction; regulation of extrinsic apoptotic signaling pathway; and ripoptosome assembly involved in necroptotic process. Predicted to be located in mitochondrion. Predicted to be part of death-inducing signaling complex; receptor complex; and ripoptosome. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; immune system; limb; liver; and lung. Human ortholog(s) of this gene implicated in immunodeficiency 57. Orthologous to human RIPK1 (receptor interacting serine/threonine kinase 1). [provided by Alliance of Genome Resources, Jul 2025]	13	34181072	34219153	Mouse	516	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1322238	Cradd	CASP2 and RIPK1 domain containing adaptor with death domain	Predicted to enable death domain binding activity; protease binding activity; and protein-macromolecule adaptor activity. Acts upstream of or within positive regulation of apoptotic signaling pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including branchial arch; cen ... (more) tral nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 34. Orthologous to human CRADD (CASP2 and RIPK1 domain containing adaptor with death domain). [provided by Alliance of Genome Resources, Jul 2025]	10	95010601	95160000	Mouse	138	old_gene_name , name , description	gene, protein-coding, VALIDATED [RefSeq]