| 1552942 | Rhob | ras homolog family member B | Enables GDP binding activity. Involved in several processes, including positive regulation of angiogenesis; positive regulation of apoptotic process; and regulation of modification of postsynaptic structure. Acts upstream of or within intracellular protein transport. Located in endosome; nucleus; an d plasma membrane. Is active in Schaffer collateral - CA1 synapse. Is expressed in several structures, including branchial arch; central nervous system; embryo ectoderm; heart; and sensory organ. Orthologous to human RHOB (ras homolog family member B). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 8547661 | 8550009 | Mouse | 374 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1315736 | Rhobtb1 | Rho-related BTB domain containing 1 | Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including cytoskeleton organization; regulation of actin cytoskeleton organization; and regulation of cell shape. Predicted to be active in several cellular components, including cytoplasmic vesicle; cytoskeleton; and plasma membrane. Is expressed in several structures, including genitourinary system; heart; liver; lung; and stomach. Orthologous to human RHOBTB1 (Rho related BTB domain containing 1). [provided by Alliance of Genome Resources, Apr 2025] | 10 | 68987106 | 69127621 | Mouse | 162 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1320530 | Rhobtb2 | Rho-related BTB domain containing 2 | Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including cytoskeleton organization; regulation of actin cytoskeleton organization; and regulation of cell shape. Predicted to be active in several cellular components, including cytoplasmic vesicle; cytoskeleton; and plasma membrane. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; integumental system; and nervous system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 64. Orthologous to human RHOBTB2 (Rho related BTB domain containing 2). [provided by Alliance of Genome Resources, Apr 2025] | 14 | 70022439 | 70062296 | Mouse | 124 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1323268 | Rhobtb3 | Rho-related BTB domain containing 3 | Predicted to enable ATP binding activity; ATP hydrolysis activity; and enzyme binding activity. Acts upstream of or within male gonad development. Located in cytoplasm. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; respiratory system; and ske letal musculature. Orthologous to human RHOBTB3 (Rho related BTB domain containing 3). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 76017656 | 76092054 | Mouse | 173 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1312227 | Arhgef2 | Rho/Rac guanine nucleotide exchange factor 2 | Enables guanyl-nucleotide exchange factor activity and microtubule binding activity. Involved in several processes, including asymmetric neuroblast division; establishment of mitotic spindle orientation; and positive regulation of neuron migration. Acts upstream of or within several processes, inclu ding actin filament organization; negative regulation of podosome assembly; and regulation of Rho protein signal transduction. Located in several cellular components, including dendritic shaft; podosome; and postsynaptic density. Is expressed in several structures, including brain; dorsal root ganglion; liver; and testis. Used to study neurodevelopmental disorder with midbrain and hindbrain malformations. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with midbrain and hindbrain malformations. Orthologous to human ARHGEF2 (Rho/Rac guanine nucleotide exchange factor 2). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 88500427 | 88556839 | Mouse | 264 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |